Name | Selank |
CAS number | 129954-34-3 |
EINECS number | 232-660-2 |
Synonym | Selank; Selank Peptide; TP7; TP 7; TP-7; N-Acetyl Selank Amidate; L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-proline; Selank Acetate; PL14736; |
Description | Selank is a synthetic peptide developed as a potential therapeutic agent with various neuroprotective and cognitive-enhancing properties. It is derived from the endogenous tetrapeptide tuftsin, which plays a role in regulating the immune system and central nervous system function.
Selank has been studied primarily for its anxiolytic (anti-anxiety) effects, with research indicating that it can reduce anxiety symptoms without causing significant side effects such as blood pressure drops, which are common with traditional anxiolytics like benzodiazepines. Additionally, Selank has shown promise in enhancing cognitive functions, including memory consolidation and learning processes. Studies have demonstrated that Selank can improve memory trace stability and enhance the metabolism of serotonin (5-HT), a neurotransmitter crucial for mood regulation and cognitive function.
Selank also exhibits neuroprotective effects, potentially reversing memory impairments caused by alcohol abuse and promoting neuroplasticity through the modulation of neurotransmitter systems and the increase of Brain-Derived Neurotrophic Factor (BDNF) levels. Furthermore, it has been suggested that Selank could help manage stress-related conditions by modulating immune responses and reducing inflammation. |
Structure |  |
Molecular Formula | C33H57N11O9 |
Molecular Weight | 751.87 g/mol |
Appearance | Solid powder |
Quality Standard | Enterprise Standard |
Assay | ≥98% |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Storage Condition | Store in cool place. Keep container tightly closed in a dry and well ventilated place. |
Shelf Life | >2 years if stored properly |
Sample package | Aluminium foil bag |
Commercial package | Aluminium Tin, Fiber drum |
Origin | China |
Selank is a synthetic peptide derived from the naturally occurring peptide tuftsin, which is associated with immune function. It is primarily recognized for its anxiolytic (anxiety-reducing) and nootropic (cognitive-enhancing) properties. Developed in Russia, Selank has been studied for its potential benefits in treating anxiety disorders, enhancing memory and learning, and improving overall cognitive function.
Mechanism of Action
Selank's mechanism involves several key actions:
GABA Modulation: Selank is thought to modulate the GABAergic system, enhancing the effects of GABA (gamma-aminobutyric acid), a major inhibitory neurotransmitter in the brain. This modulation may help reduce anxiety and promote relaxation without the sedative effects commonly associated with traditional anxiolytics.
Neurotransmitter Regulation: It influences levels of serotonin, noradrenaline, and dopamine, which are critical for mood regulation and cognitive functions. Increased serotonin levels can improve mood and appetite while reducing anxiety.
Brain-Derived Neurotrophic Factor (BDNF) Enhancement: Selank has been shown to increase BDNF levels, which are essential for neuroplasticity, learning, and memory. This effect may contribute to its cognitive-enhancing properties.
Applications
Selank is indicated for:
Generalized Anxiety Disorder (GAD): Clinical trials suggest it can effectively reduce anxiety symptoms without the sedative effects or addiction risks associated with benzodiazepines.
Cognitive Enhancement: It may improve memory, learning abilities, and overall cognitive function.
Stress Reduction: Selank can help manage stress responses and improve resilience to stressors.
Immune Function Support: By modulating immune responses, it may enhance the body's ability to fight infections.
Routes of Administration
Selank is primarily administered via:
Intranasal Spray: This method allows for effective delivery directly into the bloodstream and brain.
Subcutaneous Injection: An alternative route that may be used in certain clinical settings.
Safety and Side Effects
Common Side Effects
While Selank is generally considered safe, some users report mild side effects, including:
Nasal irritation or discomfort (when administered as a nasal spray)
Headaches
Fatigue
Dizziness
Mild gastrointestinal discomfort
Serious Side Effects
Serious adverse effects are rare but can include:
Allergic reactions (e.g., rash, swelling)
Changes in blood pressure or heart rate
Severe headaches or visual disturbances
Precautions
Caution should be exercised in individuals with allergies to peptides or those with pre-existing health conditions. It's advisable to consult healthcare professionals before starting Selank therapy.
Pharmacokinetics
Absorption and Distribution
Selank is rapidly absorbed through the nasal mucosa when administered as a spray. Its pharmacokinetic profile indicates quick onset of action due to direct absorption into systemic circulation.
Metabolism and Excretion
As a peptide, Selank is likely metabolized by proteolytic enzymes in the body. Detailed studies on its metabolic pathways are limited.
Q1. Can I get a free sample?
We can send you a samll free sample, and you only need to pay for the shipping cost.
Q2. What is the HyperChem payment term?
T/T in advance
LC at sight
DP at sight
Bank transfer
PayPal
Bitcoin...
Q3. What is HyperChem shipment policy?
Our policy is to strive for the quickest shipment time possible.
For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.
Q4. What is HyperChem shipment term?
By Express
FedEx UPS DHL EMS
Fast: 3-7 days around, high cost, door to door service
By Air
Suitable for more than 50kg
Fast: 3-7 days, hight cost, port to port, professional broker needed
By Sea
Suitable for more than 500kg
Fast: 7-45 days, low cost, port to port, professional broker needed
We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.
Q5. What HyperChem will provide after shipment?
For sample orders:
After shipment is done, an timely email including:
1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice
For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.
Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.
Among them, our key client industrial sectors around the global are:
Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply
HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.
United States
Greece
Italy
Oman
Brazil
United Kingdom
Poland
