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Weight Loss Retatrutide 20mg 5mg

7433 Inquiries

Unit Price: Get Latest Price
CAS No.:

2381089-83-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Qingdao

Packaging:

10vials/box

Price valid (until):

2025-11-30

Company Type:
Trader
Location:
Hongkong, China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

  • Product Details

  • Seller Information

  • Inquiry History

  • Description

    Weight Loss Retatrutide 20mg 5mg Description

    Product Description

    CAS No.:

    2381089832
    Name: Reta
    Purity: 99%
    Package: 1mg\g\kg/RMB 100;1mg\g\kg1mg\g\kg
    Colour White lyophilized
    Appearance Powder


    Weight Loss Retatrutide 20mg 5mg is a long-acting glucagon like peptide-1 receptor agonist that can inhibit glucagon secretion, reduce weight, and achieve weight loss by binding to the glucagon like peptide-1 receptor. Ritalin can achieve weight loss by inhibiting glucagon secretion, delaying gastric emptying, suppressing appetite, and promoting energy metabolism. It can be improved through dietary adjustments, regular exercise, medication therapy, surgical treatment, and other methods.


    How Do Retatrutide Receptor Agonists Work?

    Different receptor agonists have different effects in our bodies, depending on which cell receptors they bind to. Retarglutide activates three receptor agonists: GLP-1, GIP, and glucagon. To better understand how retarglutide works, you must understand these receptor agonists. Here, we'll explain how each works in our bodies and why they help with weight loss:

    Shop Weight Loss Retatrutide 20mg 5mg-Detailed Image 1

    In clinical trials, retatrutide has shown significant weight loss effects. A mid-term study showed that obese patients who received the highest dose of ritaglutide treatment within 48 weeks experienced an average weight loss of 24%, which is almost equivalent to the level of weight loss surgery. In addition, a considerable proportion of patients have lost 30% or more in weight. These clinical trial results were published in the New England Journal of Medicine and have received widespread attention and recognition from medical peers.
    However, it is worth noting that ritaglutide also has some side effects, the most common of which are gastrointestinal symptoms such as nausea, diarrhea, etc. These side effects are dose-dependent and are milder at lower initial doses. Therefore, when using Ritaglutide for weight loss treatment, it is necessary to do so under the guidance of a doctor to ensure safe and effective use of the medication.
    Overall, ritaglutide is a novel drug with significant weight loss effects, but attention should be paid to its side effects and safety issues when using it. If you are considering using Ritaglutide for weight loss treatment, please be sure to consult a professional doctor or pharmacist for advice.


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    ECHEMI Editorial Reference
    Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.
    Retatrutide (LY-3437943) was discovered by the American pharmaceutical company Eli Lilly and Company. It is a triple glucagon hormone receptor agonist (GLP-1, GIP, and GCGR receptors) for obesity. The 2024 Lasker~DeBakey Clinical Medical Research Award has been given to Joel Habener and Svetlana Mojsov for their discovery of a new hormone GLP-1(7-37) and to Lotte Knudsen for her role in developing sustained acting versions of this hormone as a treatment for obesity.

    Basic Info
    Product Name:

    Retatrutide

    Other Name:

    Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

    CAS No.:

    2381089-83-2

    InChIKeys:

    MLOLQJNKXBNWFW-SAGGEDDASA-N

    Molecular Weight:

    0

    EC Number:

    200-001-8

    Color/Form:

    White lyophilized

    Categories:

    Other Chemical Drugs

    Characteristics
    Water Solubility:

    Soluble in water (5mg/ml).

    Storage Conditions:

    -20°C

    Critical Temperature & Pressure:

    -20°C

    Research
    Class:

    Triple agonist — GCGR, GIPR, GLP-1R

    Status:

    Investigational (Phase 3)

    Mechanism:

    Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

    EC50 (Human GCGR):

    5.79 nM

    EC50 (Mouse GIPR):

    0.191 nM

    EC50 (Mouse GLP1R):

    0.794 nM

    EC50 (Mouse GCGR):

    2.32 nM

    EC50 (Human GLP1R):

    0.775 nM

    EC50 (Human GIPR):

    0.0643 nM

    Source:

    Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

    Clinical Development:

    NCT04881760; NCT05882045; NCT06354660

    References
    ChEMBL:

    CHEMBL5095485

    DrugBank:

    DB18993

    KEGG DRUG:

    D12430

    PubChem:

    PubChem

    Disclaimer:

    Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

    Location:

    Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $50 million-$100 million

    Total Employees:

    51-100

    Year of Establishment:

    2012

    We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

    In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

    Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

    "Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.

  • Inquiry History
    7433 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Retatrutide 2381089-83-2

    3 MT Mar 28, 2026
    United Kingdom

    Retatrutide - 2381089-83-2

    1 G Feb 10, 2026
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    Retatrutide CAS 2381089-83-2 10mg vial

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    5 KG Nov 10, 2025
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    1 MT Mar 22, 2026
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    2381089-83-2

    100 G Jul 14, 2026
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    2381089-83-2

    100 G Feb 24, 2026
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    2381089-83-2

    100 MT Dec 9, 2023
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    Retatrutide 2381089-83-2

    200 MG May 16, 2026
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    2381089-83-2 retatrutide

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    500 MT Nov 3, 2023
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    CAS 2381089-83-2 (Custom Peptide)

    40 MT Apr 10, 2026
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    10 PCS Feb 21, 2026
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