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Home > Active Pharmaceutical Ingredients > Feed Additive > Choline chloride for Sale > China origin Rumen-protected Choline Chloride used for reducing liver fat deposition and improving postpartum lactation performance in dairy cows
China origin Rumen-protected Choline Chloride used for reducing liver fat deposition and improving postpartum lactation performance in dairy cows buy - large image1
China origin Rumen-protected Choline Chloride used for reducing liver fat deposition and improving postpartum lactation performance in dairy cows buy - image1
China origin Rumen-protected Choline Chloride used for reducing liver fat deposition and improving postpartum lactation performance in dairy cows buy - image2
China origin Rumen-protected Choline Chloride used for reducing liver fat deposition and improving postpartum lactation performance in dairy cows buy - image3
China origin Rumen-protected Choline Chloride used for reducing liver fat deposition and improving postpartum lactation performance in dairy cows buy - image4
China origin Rumen-protected Choline Chloride used for reducing liver fat deposition and improving postpartum lactation performance in dairy cows buy - image5
China origin Rumen-protected Choline Chloride used for reducing liver fat deposition and improving postpartum lactation performance in dairy cows buy - image6

China origin Rumen-protected Choline Chloride used for reducing liver fat deposition and improving postpartum lactation performance in dairy cows

45 Inquiries

Unit Price: Get Latest Price
CAS No.:

67-48-1

Grade:

Feed Grade

Content:

30%

Port:

Qingdao, Shanghai or Beijing

Brand:

HANDOM CHEM

Packaging:

25kg/Kraft Paper Bag

Price valid (until):

2025-11-30

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Details  


    Product Name: Rumen-protected Choline Chloride

    Synonyms: Rumen Protected Choline Chloride; Rumen-protected Choline; Rumen protected Choline(RPC); Rumen-protected Choline Feed Grade; Rumen-protected Choline 25%; Rumen-protected Choline 30%; Rumen-protected Choline 50%; Rumen-protected Choline 60%

    Content: 25%/30%/50%/60%

    Grade: Feed Grade


    1. Brief Introduction:

    Rumen-Protected Choline Chloride, also called Rumen-Protected Choline (RPC), which is a feed additive specially designed for ruminants (such as cattle and sheep). Through special processing (such as coating technology), choline chloride is not degraded by microorganisms in the rumen, so it can be effectively absorbed in the small intestine and exert its physiological function.

    Shop China origin Rumen-protected Choline Chloride used for reducing liver fat deposition and improving postpartum lactation performance in dairy cows-Detailed Image 1


    2. Core Concepts:

    1) Choline Chloride:
    It is the chloride form of choline and belongs to the water-soluble vitamin class, it participates in important physiological processes such as fat metabolism, liver function, and nerve signal transmission in animals.
    ♔ Function: Prevent fatty liver, promote lipid metabolism, and improve milk production, reproductive performance, and immunity.

    2) Rumen Protected Technique (Rumen-passing Technology):
    There are a large number of microorganisms in the rumen of ruminants, and ordinary choline chloride is easily decomposed and ineffective. Rumen Protected Technique protects choline chloride by coating (such as fat, polymer) or chemical modification, so that it is stable in the rumen, and is released and absorbed only after entering the true stomach (abomasum) and small intestine, thereby achieving the purpose of improving feed utilization.


    3. Product Efficacy:

    1) Reduce blood free fatty acids and protect the liver;

    2) Prevent negative energy balance in dairy cows after delivery and reduce metabolic diseases such as ketosis and fatty liver in dairy cows;

    3) Increase milk production, increase milk fat and milk protein content;

    4) Prolong the peak lactation period;

    5) Improve reproductive performance.


    Test Items Specifications
    Appearance White or yellowish granules with good fluidity
    Choline Chloride Content Not less than 25%
    Carrier Palm Oil
    Loss on Drying Not more than 8%
    Particle Size 100% pass through 10 mesh sieve


    4. Main Application Scenarios:

    1) Dairy Cattle Farming:
    - Prevent metabolic diseases such as fatty liver and ketosis during the peripartum period (before and after delivery).
    - Increase milk production and milk fat rate, and improve reproductive performance.

    2) Beef Cattle/Sheep Fattening:
    - Promote muscle growth, reduce fat deposition, and improve feed conversion rate.


    5. Recommended Dosage:

    ☝ Peripartum Dairy Cows: 3 weeks before calving to 3 weeks after calving, 30-50 g/head/day.

    ☝ Lactating Dairy Cows: Add as appropriate, 10-30 g/head/day.

    ☝ Beef Cattle and Mutton Sheep: 1-2 kg/ton of concentrate feed or use according to the formulator's recommendations.


    6. Advantages and Necessity:

    ★ Solve the Absorption Problem: Ordinary choline chloride has a very low utilization rate in the rumen (<10%), but rumen protected technique can increase its absorption rate to more than 50%.

    ★ Metabolic Health: Choline supplementation can reduce liver fat accumulation and maintain energy balance, which is especially important for high-yielding dairy cows.

    ★ Economic Benefits: The breeding costs can be greatly reduced by improving production performance and disease prevention capabilities.


    7. Test Data Support:

    Choose 14 perinatal Holstein cows with similar health status for a randomized controlled trial:
    Preliminary trial period was 7 days, Trial period was 4 weeks, Choose the mixed diet on the farm as the basic diet, Use the same diet composition,dosage and feeding method in control group and experimental group.
    Control Group: Basic diet
    Experimental Group: Basic diet+Rumen-protected Choline Chloride 20g (day/head)


    Effects on the milk production performance of the cows in early lactation after adding

    Rumen-protected Choline Chloride (n=7)

    Items Group Calving

    Postpartum

    10 days

    Postpartum

    20 days

    Postpartum

    45 days

    Milk Production/kg Control group 21.8±3.6 22.6±2.4 23.8±1.5 25.2±3.2
    Experimental group 21.5±2.8 21.8±2.2 22.1±2.6 22.7±2.3
    Milk Protein Percentage/kg Control group 3.10±0.12 3.08±0.09 3.08±0.11 3.05±0.08
    Experimental group 3.09±0.11 3.06±0.10 3.05±0.07 3.04±0.09
    Milk Fat Percentage/kg Control group 4.12±0.12 4.14±0.09 4.18±0.13 4.23±0.12
    Experimental group 4.11±0.09 4.12±0.11 4.15±0.08 4.17±0.10


    This shows:
    1. Compared to the control group, the biggest volume variance of milk production occurs in the calving time, and this volume variance gets smaller with the progress of the lactation period.

    2. The protein percentage and fat percentage of the experimental group show a little higher than control group.

    3. To a certain degree, adding rumen-protected choline chloride could help to improve the milk production performance during the lactation period.




    The degradation trial of rumen-protected choline chloride on the rumen of sheep

    The degradation percentage of coated choline chloride in rumen within 24 hours is lower than 30%, while the degradation percentage of uncoated choline chloride in rumen within 30 minutes is over 60%, and over 70% within 24 hours. Thus it shows that the coated choline chloride can be well preserved in the rumen of ruminant.


    Effects comparison of uncoated choline chloride and coated choline chloride

    Shop China origin Rumen-protected Choline Chloride used for reducing liver fat deposition and improving postpartum lactation performance in dairy cows-Detailed Image 2

    8. Note:

    ※ Dosage Control: Overdose may cause choline poisoning or interfere with the absorption of other nutrients.

    ※ Synergy with Other Additives: It needs to be combined with Rumen-protected Methionine, Vitamin B12, etc. to optimize the metabolic effect.

    ※ Storage Conditions: Avoid high temperature and humid environment that may cause the coating material to fail.


    9. Packaging of our Rumen-protected Choline Chloride:

    25Kg/Kraft Paper Bag, 1000Kg packed on one pallet.


    Shop China origin Rumen-protected Choline Chloride used for reducing liver fat deposition and improving postpartum lactation performance in dairy cows-Detailed Image 3

    Shop China origin Rumen-protected Choline Chloride used for reducing liver fat deposition and improving postpartum lactation performance in dairy cows-Detailed Image 4


    10. Shelf Life:

    12 months from the date of manufacturing when stored under the above conditions.

    Basic Info
    Product Name:

    Choline chloride

    Other Name:

    Ethanaminium,2-hydroxy-N,N,N-trimethyl-,chloride (1:1);Choline,chloride;Ethanaminium,2-hydroxy-N,N,N-trimethyl-,chloride;Biocolina;Hepacholine;(2-Hydroxyethyl)trimethylammonium chloride;Lipotril;Cholinium chloride;(β-Hydroxyethyl)trimethylammonium chloride;Bilineurin chloride;Luridin chloride;Biocoline;Hormocline;Neocolina;Paresan;Trimethyl(2-hydroxyethyl)ammonium chloride;Actiron CC 6;Choline chloride;Norcol 25;COL 24;ReaShure Choline;Claytreat;(2-Hydroxyethyl)trimethylazanium chloride;1643859-93-1;2028303-08-2

    CAS No.:

    67-48-1

    Molecular Formula:

    C5H14NO.Cl

    InChIKeys:

    InChIKey=SGMZJAMFUVOLNK-UHFFFAOYSA-M

    Molecular Weight:

    139.624

    Exact Mass:

    139.076

    EC Number:

    200-655-4

    UNII:

    45I14D8O27

    ICSC Number:

    0853

    NSC Number:

    758473|402838

    DSSTox ID:

    DTXSID4020325

    Color/Form:

    WHITE CRYSTALS|Deliquescent crystals

    HScode:

    2923100000

    Categories:

    Feed Additive

    Characteristics
    PSA:

    20.23

    XLogP3:

    log Kow = -5.16 (est)

    Appearance:

    White crystalline powder

    Density:

    1.205 g/cm3

    Melting Point:

    305 °C (decomp)

    Water Solubility:

    H2O: soluble

    Storage Conditions:

    0-6ºC

    Toxicity:

    LD50 in rats (g/kg): 0.400 i.p.; 6.64 orally (Hartung, Cornish)

    PH:

    4.7 (10% SOLN IN WATER)

    Collision Cross Section:

    121 Ų [M]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Experimental Properties:

    Aq soln is practically neutral

    Air and Water Reactions:

    Deliquescent. Very soluble in water. (NTP, 1992)

    Reactive Group:

    Alcohols and Polyols

    Reactivity Profile:

    Choline chloride is a quaternary ammonium salt. Quaternary ammonium salts often serve as catalysts in reactions. They are incompatible with many strong oxidizers and reducing agents, such as metal hydrides, alkali/active metals, and organometallics. Quaternary ammonium salts often serve as catalysts in reactions. They are incompatible with many strong oxidizers and reducing agents, such as metal hydrides, alkali/active metals, and organometallics. Unlike the ammonium ion, [NH4]+, and the primary, secondary, or tertiary ammonium cations, the quaternary ammonium cations are permanently charged, independent of the pH of their solution.

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Separated from strong oxidants.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

    Location:

    RM702, Building 21, Liuhe Road, Ganjingzi Dist, Dalian, Liaoning, China

    Payment Terms:

    TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    15

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    51-100

    Year of Establishment:

    2020

    Dalian Handom Chemicals Co., Ltd.(HDC CHEM) is a professional 15-Year-Experienced Supplier of APIs & Intermediates, Pharmaceutical Excipients, Food & Nutraceutical Ingredients, Personal Care Chemicals and Specialty Chemicals from northeast of China, which strives to provide customers with high-quality products and comprehensive service across all over the world, our main products cover Retatrutide Lyophilized Powder, Retatrutide, Tirzepatide, Tirzepatide Lyophilized Powder, Semaglutide, Mazdutide, Cagrilintide, LL-37, Thymosin Alpha 1(Thymosin α1), MT-2, MOTS-c, HEP-1, TB-500, NAD+, GHK-Cu, Glow, Klow, Selank, Semax, Glutathione, 5-Amino-1MQ, ARA-290, SS-31, DSIP, SNAP-8, Medetomidine, Medetomidine Hydrochloride, Salcaprozate Sodium, Sodium 8-(2-hydroxybenzamido)octanoate, 2,6-Dimethyl Beta Cyclodextrin, mPEG-DMG-2K, mPEG-DSPE-2K, 1,2-Distearoyl-sn-3-phosphacholine(DSPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), Pharmaceutical Grade Fructose, Lactose Anhydrous, Lactose Monohydrate, Orotic acid anhydrous, Orotic acid monohydrate, 6-Methyluracil, Chitosan, Mushroom Chitosan, Chitosan Hydrochloride, Chitosan Oligosaccharide, Alginate Oligosaccharide, Inulin, L-Serine, Mung Bean Peptide, Walnut Peptide, Rice Peptide, Oyster Peptide, Sea Cucumber Peptide, Hydrolyzed Keratin, Folic Acid, Vitamin E Acetate, Vitamin B2, Riboflavin Sodium Phosphate, Pyridoxal 5'-phosphate Monohydrate, Vegan Vitamin D3, Vitamin A Palmitate, Vitamin A Acetate, Apple Pectin, Citrus Pectin, Sunflower Pectin, Salidroside, Urolithin A, Milk Thistle Extract, Saffron Extract, Red Clover Extract, Sulforaphane, Glucoraphanin, Soy Isoflavones, Soy Lecithin, Soya Lecithin, Egg Yolk Lecithin, Phosphatidylserine, Cooling Agent WS-3, Cooling Agent WS-5, Cooling Agent WS-10, Cooling Agent WS-12, Cooling Agent WS-23, Cooling Agent WS-27, Menthyl Lactate, Menthyl PCA, Avobenzone, Benzophenone-3 (UV-9), Benzophenone-4 (UV-284), Bis-ethylhexyloxyphenol Methoxyphenyl Triazine (Bemotrizinol), Diethylaminohydroxybenzoyl Hexyl Benzoate (UVA Plus), Diethylhexyl Butamido Triazone (Iscotrizinol), Disodium Phenyl Dibenzimidazole Tetrasulfonate (DPDT), Ethylhexyl Triazone (UVT-150), Homosalate, Octocrylene, 2-Ethylhexyl Salicylate (Octyl Salicylate), 2-Ethylhexyl Trans-4-Methoxycinnamate (OMC), 2-Phenylbenzimidazole-5-Sulfonic Acid (UV-T), Lanolin Anhydrous, Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Biotinoyl Tripeptide-1, etc.

  • Inquiry History
    45 Inquiries
    Country Product Purchase Quantity Date Posted
    Paraguay

    Choline chloride

    200 KG Oct 27, 2025
    Hongkong, China

    Choline chloride

    150 MT Jul 21, 2023
    Paraguay

    Choline chloride

    200.00 KG Sep 25, 2025
    United Arab Emirates

    Choline Chloride

    100 MT May 26, 2026
    Indonesia

    choline chloride food grade 7.2 MT(combine into 1x20 FCL)

    7.2 MT Apr 13, 2026
    United Kingdom

    Choline chloride 97.6% White crystalline powderl

    1000 KG Mar 31, 2026
    United States

    choline chloride TGAI

    2 KG Jan 13, 2026
    India

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    120 MT Mar 12, 2025
    Czech

    Choline Chloride

    179000 KG Dec 16, 2024
    Kazakstan

    Choline chloride

    20 TON Nov 18, 2024
    China

    Cholinechloride 60% with ISO

    150 MT Oct 10, 2023
    Philippines

    Choline chloride

    25.00 KG Sep 16, 2023
    India

    best price feed grade choline chloride 60% corn cob powder for poultry and aquaculture

    150 MT Jul 27, 2023
    Philippines

    Choline Chloride 99% 0.3 1477 Choline Chloride

    1 KG Jun 27, 2023
    Thailand

    Choline chloride

    23 MT Apr 8, 2026
    India

    CHOLINE CHLORIDE 60%

    2 20' Fcl Jun 25, 2025
    Malaysia

    Choline Chloride

    500 KG Apr 9, 2025
    United Arab Emirates

    Choline Chloride

    2 20' Fcl Mar 31, 2025
    Indonesia

    Choline chloride

    1 MT Jan 16, 2025
    Bangladesh

    Choline chloride

    1.00 KG May 16, 2024
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