Diosmetin
1 Inquiries
520-34-3
Industrial Grade
99%
ailike
25kg/Cardboard Drum
Yes
2026-06-01
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
-
Product Description
-
Seller Information
-
Inquiry History
-
DescriptionECHEMI Editorial ReferenceDiosmetin is a natural flavonoid which inhibits human CYP1A enzyme activity with an IC50 of 40 μM in HepG2 cell.
Solid
Diosmetin is a monomethoxyflavone that is the 4'-methyl ether derivative of luteolin. It is a natural product isolated from citrus fruits which exhibits a range of pharmacological activities. It has a role as an antioxidant, an antineoplastic agent, a plant metabolite, a tropomyosin-related kinase B receptor agonist, an apoptosis inducer, an angiogenesis inhibitor, a cardioprotective agent, a bone density conservation agent, an anti-inflammatory agent and a vasodilator agent. It is a monomethoxyflavone, a trihydroxyflavone and a 3'-hydroxyflavonoid. It derives from a luteolin.|Diosmetin is an O-methylated flavone and the aglycone part of the flavonoid glycosides diosmin that occurs naturally in citrus fruits. Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant, oestrogenic and anti-inflamatory activities. It also acts as a weak TrkB receptor agonist.Basic Info-
Product Name:
Diosmetin
Other Name:4H-1-Benzopyran-4-one,5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-;Diosmetin;Flavone,3′,5,7-trihydroxy-4′-methoxy-;5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one;Diosmetol;Diosmetine;3′,5,7-Trihydroxy-4′-methoxyflavone;Luteolin 4′-methyl ether;5,7,3′-Trihydroxy-4′-methoxyflavone;4′-Methylluteolin;Pillon
CAS No.:520-34-3
Molecular Formula:C16H12O6
InChIKeys:InChIKey=MBNGWHIJMBWFHU-UHFFFAOYSA-N
Molecular Weight:300.26
Exact Mass:300.26
EC Number:208-291-8
UNII:TWZ37241OT
DSSTox ID:DTXSID80199966
Color/Form:Yellow powder
HScode:2914509090
Categories:
Characteristics-
PSA:
96.2
XLogP3:1.7
Appearance:light yellow to yellow
Density:1.512 g/cu cm
Melting Point:253.5 °C
Boiling Point:576.7°C at 760 mmHg
Flash Point:220.3±23.6 °C
Refractive Index:1.697
Water Solubility:DMSO: soluble 1mg/mL, clear, light yellow to yellow
Storage Conditions:-20°C Freezer
Vapor Pressure:3.8X10-12 mm Hg at 25 deg C (est)
Henrys Law Constant:Henry's Law constant = 3.0X10-18 atm-cu m/mol at 25 °C (est)
Collision Cross Section:164.8 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Experimental Properties:Hydroxyl radical reaction rate constant = 2.3X10-10 cu cm/molecule-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2-8 deg C
-
-
Seller Information
-
Business Type:
Trader
-
Main Products:
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
-
Location:
Huangdao District, Qingdao City, Shandong Province (formerly Room 606-2, Building 1, No. 10 Beijing Road, Jiaonan City)
-
Payment Terms:
TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance
-
Average lead Time:
15 days
-
Total Annual Revenue:
$5 million-$10 million
-
Total Employees:
51-100
-
Year of Establishment:
2023
Company Certificates-
Credit rating certificate
-
Hazardous Chemicals Business License
-
-
Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
Nigeria
Diosmetin
250 MG Apr 5, 2026 Post an enquiry for this product
More from this Seller
-
-
-
Glyceryl Monooleate 99% yellow to reddish brown liquid 111035
Pharmaceutical Grade / 0%
-
-
-
-
2-Ethylhexyl bromide cas18908-66-2
Pharmaceutical Grade / 99%
-
-
-
-
ISOBUTANE 99% Coless liquid
Pharmaceutical Grade / 0%
-
-
-
-
Tetrachloroterephthalonitrile
Analytical Reagent / 99%
-
-
-
-
Solvent Blue 97
pharmaceutical grade / 99%
-
-
-
-
924-50-5Methyl 3-methyl-2-butenoate
Industrial Grade / 99%
-