GLP-1 Peptides Purity 99% CAS 2381089-83-2 Weight loss Obesity Treatment 60mg Tirz(LY3437943)

Product Description
Tirzepatide is a novel glucagon-like peptide-1 receptor (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP, aka: gastric inhibitory polypeptide) dual receptor agonist, administered once a week. both GLP-1 and GIP belong to the intestinal proinsulin, which is a polypeptide secreted by the mucous membranes of the gastrointestinal tract of the human body. the former can bind with the receptor on the pancreatic islet cell and stimulate the secretion of islet Chemicalbookin, which in turn produces a hypoglycemic effect, as well as delaying gastric emptying and suppressing appetite, thereby controlling body weight; whereas the latter has the functions of inhibiting gastric acid and pepsin secretion, stimulating insulin release, and inhibiting gastric peristalsis and emptying, which can complement the GLP-1 receptor agonist effect. tirzepatide combines the effects of 2 types of insulinotropic agents in a a single molecule and represents a novel class of drugs for the treatment of type 2 diabetes.
Uses
Tirzepatide shares a similar sequence to semaglutide, with the lys side chain of the sequence bearing a PEG modification, which is a functional group of the peptide, as well as the ability to increase the water solubility of the sequence.The primary physiological function of Tirzepatide is that of a dual agonist of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor. It is being developed for the treatment of type 2 diabetes mellitus and is already in the clinical phase.A large study enrolled 2539 adults with at least one complication of obesity (excluding diabetes) and a body mass index (BMI) ≥30kg/m2 or ≥27kg/m2. All subjects were randomly divided into 5mg, 10mg, 15mg and placebo groups in equal proportions. The results showed that at 72 weeks, the weight of each group decreased by 16.1kg, 22.2kg, 23.6kg, and 2.4kg, respectively [2]. The weight loss effect of tepoxetine is comparable to that of bariatric surgery.
Application 

1.Helps slow food leaving your stomach
2.Helps prevent your liver from making too much sugar
3.Helps the pancreas produce more insul when your blood sugar levels are high
4.Can help control blood glucose
5.Can reduce hyperglycemia, especially after meals
6.Can reduce fasting insul and fasting glucose
7.Can reduce hemoglobin A1c
8.Can decrease appetite and caloric intake, while inhibiting weight gain
9.Has been shown to lower triglyceride levels and oxidative stress from high LDL