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supply Best Price High Quality Antiallergic Drug CAS 83881-51-0 Cetirizine Powder

Name: supply Best Price High Quality Antiallergic Drug CAS 83881-51-0 Cetirizine Powder
Brand: First Chems Co., LTD
SKU: pr2504241431
Price: 110 USD
Availability: InStock

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CAS No.:

83881-51-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

qingdao

Brand:

First Chems Co., LTD

Packaging:

1kg ,25kg or according to customer's detail requirement.

Sample Available:

Yes

Price valid (until):

2025-11-27

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First Chems Co., LTD

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

Titanium dioxide,npk,pvc,sles,labsa,mdi

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Best Price High Quality Antiallergic Drug CAS 83881-51-0 Cetirizine Powder

What is Cetirizine ?

Cetirizine is an antiallergic drug, which is the second generation of H1 antihistamines and is a long-term, selective, oral, and powerful antiallergic agent. For seasonal or perennial allergic rhinitis, urticaria caused by allergens, and skin itching.

Items	Specifications
Product Name	Cetirizine
CAS No.	83881-51-0
Appearance	White Powder
Assay	98%
MF	C21H25ClN2O3
MW	388.89
Melting Point	110-115°C
Boiling Point	542.1±45.0 °C(Predicted)
Density	1.237±0.06 g/cm3(Predicted)

Shop supply Best Price High Quality Antiallergic Drug CAS 83881-51-0 Cetirizine Powder-Detailed Image 1

Certification

Technical Date Sheet:

Item	Specification	Result
Appearance	White powder	Complies
Related substance (HPLC)	Total impurity ≤0.5% Max single impurity ≤0.1%	0.2% 0.06%
Odor	Characteristic	Complies
Assay	99%	99.8%
Sieve analysis	100% pass 80 mesh	Complies
Loss on Drying Residue on Ignition	≤1.0% ≤1.0%	0.12% 0.09%
Heavy Metal	<10ppm	Complies
As	<0.1ppm	0.05ppm
Pb	<0.1ppm	0.05ppm
Cd	<0.1ppm	0.05ppm
Residual Solvents	<100ppm	Complies
Conclusion	Conform with specification CP2010

Function

Cetirizine is a second generation antihistamine used in the treatment of hay fever, allergies, angioedema, and urticaria.It is a major metabolite of hydroxyzine, and a racemicselective H1 receptor antagonist.
1. Cetirizine is mainly used for urticaria and skin itch caused by allergy ;
2. Cetirizine is used to treat tardive and pressure urticaria,can replace glucocorticoid to be as regular treatment but should be used a large amount;
3. Cetirizine can also have the function for cold urticaria.

Recommended Storage:
Cetirizine is recommended to store it in a cool, dry place, sealed from outside air. We ship the product in a double sealed bag which can be resealed. Another container is recommended sealing from outside air.

Our advantage ：

★ The company has been established for more than 10 years with rich export experience and experienced transportation team.

★ Awesome after sales.1 to 1 customer service to solve any problems from the beginning of the inquiry to the receipt of goods

★ Quality is guaranteed.

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Shipping Advise 1. By Express

------Suitable for under 50kg, Fast:3-7 days.

High cost; Door to door service. Easy to pick up the goods.

2. By Air

------Suitable for more than 50 kg, Fast:3-7 days,

High cost, airport to airport. professional broker needed.

3. By sea

------Suitable for more than 500kg. Slow: 5-45 days,

Low cost. Port to Port, professional broker needed.

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Service

1. Any inquiries will be replied within 24 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & formulation development.

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FAQ

1.How to get in touch with us?

You can chat with us by Trademanager,WhatsApp or simply giving us an email, a phone call. All our contacts information can be found from our website.

2.Are you a manufacturer or trade company?

We are a professional manufacturer.

3.Can I get a sample?

Yes, free sample can be provided, but shipping cost is covered by your side.

4.What's your MOQ?

It is based on the different product. Some are 1g while some are 1 kg. Please be free to consult our salesman.

5.When can I get the quotation?
We usually quote within 1 hours after we get your inquiry. If it's a urgent order you can call us or mention it in your email subject, and we can take it as priority.

6.Is there any discount?
Yes, some products are applied for discount, but it depends on the quantity.

7.Can you do OEM for me?
Yes,we accept OEM orders, just contact us and give us your requirement. We will offer you a reasonable price and make samples

ECHEMI Editorial Reference

Cetirizine, a second-generation antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria. IC50 value:Target: Histamine H1 receptorCetirizine crosses the blood-brain barrier only slightly, reducing the sedative side-effect common with older antihistamines. It has also been shown to inhibit eosinophil chemotaxis and LTB4 release. At a dosage of 20 mg, Boone et al. found
Solid
Cetirizine is a member of the class of piperazines that is piperazine in which the hydrogens attached to nitrogen are replaced by a (4-chlorophenyl)(phenyl)methyl and a 2-(carboxymethoxy)ethyl group respectively. It has a role as an anti-allergic agent, a H1-receptor antagonist, an environmental contaminant and a xenobiotic. It is a monocarboxylic acid, a member of piperazines, a member of monochlorobenzenes and an ether.|Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms,. One of the most common uses for this drug is for a condition called allergic rhinitis. The prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and up to 30%, according to self-reported nasal symptoms. Allergic rhinitis is associated with multiple missed or unproductive days at work and school, problems with sleep, and other difficulties with day to day activities for many individuals. Furthermore, some antihistamine agents that are used to treat this condition cause undesirable, sedating effects. Cetirizine is one of the first second-generation H1 antihistamines (SGAHs) formulated to selectively inhibit the H1 receptor without sedating effects.|Cetirizine and its enantiomer levocetirizine are second generation antihistamines that are used for the treatment of allergic rhinitis, angioedema and chronic urticaria. Cetirizine and levocetirizine have been linked to rare, isolated instances of clinically apparent acute liver injury.|A potent second-generation histamine H1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. Unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.

Certificates

Basic Info

Product Name:

Cetirizine

Other Name:

Acetic acid,2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-;Acetic acid,[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-;2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic acid;Cetirizine;(±)-Cetirizine;Cetirizin-Teva;Piriteze;Rigix;Allamine;Cetrin;Zetrinal;(2-[4-[(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-yl]-ethoxy)-acetic acid;130018-86-9

CAS No.:

83881-51-0

Molecular Formula:

C21H25ClN2O3

InChIKeys:

InChIKey=ZKLPARSLTMPFCP-UHFFFAOYSA-N

Molecular Weight:

388.89

Exact Mass:

388.89

DSSTox ID:

DTXSID4022787

Color/Form:

Crystals from ethanol

ATC Code:

R06AE07|R - Respiratory system

HScode:

2933599090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

XLogP3:

1.70

Appearance:

Solid

Density:

1.2±0.1 g/cm3

Melting Point:

112.5 °C

Boiling Point:

542.1±45.0 °C at 760 mmHg

Flash Point:

281.6±28.7 °C

Refractive Index:

1.589

Water Solubility:

In water, 6.96X10+4 mg/L at 25 deg C (est)

Storage Conditions:

Store at 20-25 deg C (68-77 deg F); excursions permitted to 15-30 deg C (59-86 deg F)

Vapor Pressure:

2.98X10-11 mm Hg at 25 deg C (est)

PKA:

1.52, 2.92 and 8.27

Henrys Law Constant:

Henry's Law constant = 4.19X10-17 cu cm/molec-sec at 25 °C (est)

Dissociation Constants:

1.52, 2.92 and 8.27|pKa1 = 2.70 (amine); pKa2 = 3.57 (carboxylic acid); pKa3 = 7.56 (amine) (est)

Collision Cross Section:

200.8 Å² [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]

Experimental Properties:

Crystals from isopropanol; mw 461.81; mp 225 °C. Soluble in water /Cetirizine dihydrochloride/|Hydroxyl radical reaction rate constant = 2.41X10-10 cu cm/molec-sec at 25 °C (est)

See More Cetirizine Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Cetirizine Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Titanium dioxide,npk,pvc,sles,labsa,mdi

Location:
37 Keji Road, Yanta District, Xi 'an City, Shaanxi Province

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
Less than 5

Year of Establishment:
2020

COMPANY OVERVIEW

First Chems Co., LTD，a joint-stock enterprise with production, export and services of chemicals, has widely adopted world-advanced equipments and management system, and our products quality is assured under the ISO9001 and ISO14001 standards, mainly specializes in developing Agriculture/Fertilizer chemicals series, Washing detergent chemicals series, Soda alkali chemicals series, Water treatment chemical series, etc.

Our main products include:

a. Agriculture/Feed chemicals series : Zinc Sulphate, Manganese sulfate etc.),

b. Washing detergent chemicals series : (LABSA, SLES, CEDA,STPP, etc.)

c. Soda alkali chemicals series : ( Caustic Soda , Sodium Sulphate Anhydrous etc.)

d. Water treatment chemical series: (Calcium hypochlorite, TCCA,SDIC, PAC- poly aluminium chloride, PFS, Aluminium sulfate etc.)

e. Adsorbent Desiccant Activated Alumina Ball

f. Raw material Calcium Aluminate ,Aluminium Hydroxide

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
Switzerland	cetirizine	1 KG	Feb 2, 2026
United States	Cetirizine HCl	25 KG	Apr 8, 2025

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supply Best Price High Quality Antiallergic Drug CAS 83881-51-0 Cetirizine Powder

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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