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Erlotinib hydrochloride 99% buy - large image1
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Erlotinib hydrochloride 99%

2 Inquiries

Unit Price: Get Latest Price
CAS No.:

183319-69-9

Grade:

Industrial Grade

Content:

99%

Port:

China

Brand:

JY

Packaging:

25kg/drum

Price valid (until):

2025-06-08

Company Type:
Trader
Location:
Hongkong, China
Qualification:
Main Products:

Peptides

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    The small molecule compound erlotinib is a receptor tyrosine kinase inhibitor that competes with adenosine triphosphate to bind to the catalytic site of the intracellular region of the receptor tyrosine kinase in cells, thereby inhibiting the phosphorylation reaction and thereby blocking the phosphorylation reaction. It has proliferation signaling, inhibits the activity of tumor cell ligand-dependent HER-1/EGFChemicalbookR, and achieves the effect of inhibiting tumor cell proliferation. Erlotinib is also another tyrosine kinase inhibitor used in the treatment of NSCLC. The results of clinical phase I trials show that its main toxicity and side effects are dose-dependent rash and diarrhea, and other rare side effects are headache, nausea and vomiting.

    Items Specifications
    Appearance White or of- white powder or crystlline power,odorless
    Solubility Very soluble in N,N-Dimethylformamide,Soluble in methanol,Sparingly soluble inglacial acetic acid, Very slightly soluble inchloroform, Practically insoluble in water.
    Melting Point 152°C~156°C

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      Company Profile


     Our company, Jianyan E-commerce Trading House in Yiwu City, is an innovative company mainly engaged in the research and development, production and sales of pharmaceutical intermediates and fine chemicals. The products are mainly used in the fields of medicine, health products, cosmetics, pesticides and electronic chemistry.

      We have a research and development centre and a production base. The R&D centre has advanced organic synthesis and analytical testing equipment. At the production base, we have large reaction vessels, including various specifications of stainless steel reaction vessels and enamel reaction vessels, capable of high-pressure,high-temperature and low-temperature reactions, with production capacities ranging from kilograms to tonnes. The company has established a comprehensive marketing network and its products are exported to countries and regions such as the United States, South Korea, Japan, India and Europe.


    Our advantage

    1. Own your own chemical plant

    2. Rich professional production experience

    3. Sample free and in stock, delivery

    4. Price, quality and service, we care about all your concerns

    5. Timely reply Keep in touch to save your time

    6. Easy customs clearance, we have all these controlsAll very good

    7. Dedicated researchers customize it for you.

    Customer Trade Show

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    FAQ

    1. I did not find what I was looking for. Do you provide specific pack sizes or different packaging?

    We are all about finding or creating the right solution for you. Our team is ready to work with you to meet your specific needs, even for small quantities. Please contact us.

    2. Can I buy samples?

    Please feel free to contact us.

    3.What is your lead time?

    It depends on the proudct and order quantity. Please contact us.

    4. How can I get a price?

    After we get your inquiry, we usually quote within 24 hours.


    5. How to confirm the quality before placing the order?

    You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.

    7. Do you provide COA?

    Yes. We'll provide certificate of analysis before shipment

    ECHEMI Editorial Reference
    Erlotinib hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM.
    Erlotinib Hydrochloride is the hydrochloride salt of a quinazoline derivative with antineoplastic properties. Competing with adenosine triphosphate, erlotinib reversibly binds to the intracellular catalytic domain of epidermal growth factor receptor (EGFR) tyrosine kinase, thereby reversibly inhibiting EGFR phosphorylation and blocking the signal transduction events and tumorigenic effects associated with EGFR activation.|A quinazoline derivative and ANTINEOPLASTIC AGENT that functions as a PROTEIN KINASE INHIBITOR for EGFR associated tyrosine kinase. It is used in the treatment of NON-SMALL CELL LUNG CANCER.

    Basic Info
    Product Name:

    Erlotinib hydrochloride

    Other Name:

    4-Quinazolinamine,N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-,hydrochloride (1:1);4-Quinazolinamine,N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-,monohydrochloride;CP 358774;OSI 774;Tarceva;6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride;[6,7-Bis(2-methoxyethoxy)quinazolin-4-yl]-(3-ethynylphenyl)amine hydrochloride;Erlotinib hydrochloride

    CAS No.:

    183319-69-9

    Molecular Formula:

    C22H23N3O4.ClH

    InChIKeys:

    InChIKey=GTTBEUCJPZQMDZ-UHFFFAOYSA-N

    Molecular Weight:

    429.89700

    Exact Mass:

    429.14600

    UNII:

    DA87705X9K

    NSC Number:

    718781

    DSSTox ID:

    DTXSID10171412

    NCI Thesaurus Code:

    C2693

    ATC Code:

    L01EB02

    HScode:

    2933990090

    Characteristics
    PSA:

    74.73000

    XLogP3:

    4.28010

    Appearance:

    White or off-white powder

    Melting Point:

    219-221 °C @ Solvent: Methanol

    Boiling Point:

    553.6ºC at 760 mmHg

    Flash Point:

    288.6ºC

    Vapor Pressure:

    4.52E-12mmHg at 25°C

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Carcinogenicity, Category 2

    Reproductive toxicity, Category 2

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H302 Harmful if swallowed

    H351 Suspected of causing cancer

    H361 Suspected of damaging fertility or the unborn child

    H411 Toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P273 Avoid release to the environment.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P318 IF exposed or concerned, get medical advice.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptides

    Location:

    Room 5003, 5th Floor, Yau Lee Centre, 45 Yuen Yuen Road, Kwun Tong, Hong Kong

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    5-10

    Year of Establishment:

    2024

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    Pakistan

    Erlotinib Hydrochloride

    1 KG Jun 23, 2025
    Pakistan

    ERLOTINIB HCL

    3.00 KG Dec 31, 2024
    Post an enquiry for this product
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