Viablife ρ-Coumaric Acid-Pharmaceutical intermediates Powder Sam

p-Coumaric acid is also known as "4-hydroxycinnamic acid" or "p-hydroxyphenylacrylic acid". Most structural types of p-coumaric acid are in the trans configuration.

As a kind of flavonoid substance, it can be converted into different phenolic acids, including high-value products such as chlorogenic acid, rosmarinic acid and flavonoids.

Moreover, p-coumaric acid has antimutagenic, antigenotoxic and antimicrobial activities, and also plays a role in human immune regulation.

ρ-Coumaric Acid is a naturally occurring polyphenol found in wine, vinegar, honey, tomatoes, basil, garlic, and various fruits.
It is a potent antioxidant that can inhibit lipid peroxidation and scavenge free radicals. Additionally, it acts as an effective antimicrobial agent against E. coli and S. aureus. When used in cosmetic products, it also demonstrates a skin-lightening effect.

Product advantages

1.Cutting-Edge Fermentation Technology
Viablife produces ρ-Coumaric Acid using a state-of-the-art production fecility and procise fermentation process, ensuring exceptonal product quality and consistency.

2.Unmatched Purity
Our ρ-Coumaric Acid achieves a purity of over 99%, setting a benchmark for excellence in the industry.

3.Clean Label and GMO-Free
Viablife's ρ-Coumaric Acid meets clean label requirements and is GMO-free, offering a natural and sustainable option for product formulators.

Product efficacy

1.Antioxidant
ρ-Coumaric Acid has radical scavenging ability in DPPH and ABTS assays.
As a natural free radical scavenger, p-coumaric acid has a strong antioxidant effect. It can minimize or prevent the oxidation of fats in food, delay the formation of toxic oxidation products, maintain the nutritional quality, and extend the shelf life of food, medicine and so on.

2.Antimicrobial
ρ-Coumaric Acid shows strong antibacterial activity against various microbial strains.

3.Anti-Melanogenic
ρ-Coumaric Acid has the optimal structure to act as a competitive inhibitor of tyrosinase, an enzyme responsible for key reactions in the melanin biosynthesis pathway. Therefore, it has good potential as a skin-lightening active ingredient in cosmetics.
ρ-Coumaric Acid can reduce skin hyperpigmentation through multiple mechanisms. UV exposure and other pathophysiological conditions stimulate the production of reactive oxygen species (ROS) and activate multiple signaling pathways, leading to increased gene expression of tyrosinase and enhanced melanin synthesis. While melanin absorbs UV radiation and helps alleviate oxidative stress and inflammation caused by UV exposure, excessive melanin deposition can result in pigmentation disorders.
ρ-Coumaric Acid, with its structural similarity to L-tyrosine, inhibits the activity of tyrosinase, which catalyzes the oxidation of L-tyrosine and/or L-DOPA to L-DOPA quinone in the melanin biosynthetic pathway. Due to its UV absorption and antioxidant properties, ρ-Coumaric Acid can inhibit signaling pathways linked to the gene expression of tyrosinase and inflammatory mediators. It can also reduce the stimulatory effects of hormones and L-tyrosine on tyrosinase gene expression. Therefore, ρ-Coumaric Acid has advantageous biochemical properties that make it a promising active ingredient for skin-lightening applications in cosmetics.

Product Application

1.Important organic chemical raw materials (intermediates)

About us

Viablife is a hightech enterprise that is specialized in enzymatic synthesis and biomanufacturing of active pharmaceutical ingredients, fine chemicals, natural dyes, pharmaceutical intermediates, and food additives. Viablife has a world class R&D team that has a broad range of experience in fermentation, enzymes, metabolic engineering and synthetic biology. Viablife has its own manufacturing center Jiangxi Viablife Biopharmaceutical Co., Ltd., a wholly owned subsidiary located in Nanchang, China. The goal of Viablife is to develop green, efficient and cost effective biomanufacturing processes for industrially natural products.