 Home > Pharmaceutical Intermediates > Antiparkinson Agents > Fasudil hydrochloride for Sale > Fasudil HCl

Fasudil HCl

Name: Fasudil HCl
Brand: Hyper Chem
SKU: pr2507231251
Price: 7 USD
Availability: InStock

4 Inquiries

Unit Price: Get Latest Price 

CAS No.:

105628-07-7

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Sample Available:

Yes

Price valid (until):

2025-08-23

Contact Supplier

 Chat Now

Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

10 days

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

 Visit Store

Product Details
Seller Information
Inquiry History

Description

Name	Fasudil
CAS number	105628-07-7
Description	Fasudil, also known as HA-1077, is a potent Rho-kinase inhibitor and vasodilator. Since it was discovered, it has been used for the treatment of cerebral vasospasm, which is often due to subarachnoid hemorrhage, as well as to improve the cognitive decline seen in stroke victims. It has been found to be effective for the treatment of pulmonary hypertension. It was demonstrated in February 2009 that fasudil could also be used to enhance memory and improve the prognosis of Alzheimers patients. It is approved for use in Japan and China.
Synonym	HA-1077; HA1077; HA 1077; HA-1077 HCl; Fasudil hydrochloride.
Related CAS	105628-07-7 (HCl) 103745-39-7 (free base) 186694-02-0 (hydrochloride hydrate)
Appearance	Solid powder
Quality Standard	USP, EP, BP, CP
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Fasudil More Info

1. Basic Information

Drug Class: Cerebral vasodilator and potent Rho-associated kinase (ROCK) inhibitor.

Developer: Developed by Asahi Kasei.

Clinical Application Scope: Widely used in Asia initially, with expanding potential in various therapeutic areas.

2. Mechanism of Action

Core Target: Acts as a specific inhibitor of Rho-associated kinase (ROCK), an enzyme involved in regulating vascular smooth muscle contraction and cell motility.

Vasodilatory Effect: By inhibiting ROCK, it relaxes vascular smooth muscle, particularly in cerebral blood vessels, thereby improving blood flow and reducing vasospasm.

3. Primary Clinical Uses

Cerebral Vasospasm Post-Subarachnoid Hemorrhage: The main indication is to improve and prevent cerebral vasospasm and the subsequent cerebral ischemic symptoms that occur after subarachnoid hemorrhage.

Pulmonary Hypertension: Shows potential therapeutic effects in the treatment of pulmonary hypertension by dilating pulmonary blood vessels.

Neurodegenerative Diseases: Recent pre-clinical studies suggest potential benefits, including reducing neurodegeneration, regulating neuroinflammation, and promoting axonal regeneration.

4. Dosage and Administration

Recommended Dosage: 30 mg of fasudil hydrochloride per dose.

Dilution Requirement: Diluted in 50 - 100 ml of appropriate solution.

Administration Method: Administered by intravenous infusion over 30 minutes.

Frequency: 2 - 3 times a day.

5. Side Effects

Cardiovascular: Hypotension, facial flushing, and reflex tachycardia may occur.

Hematological: Possible bleeding complications.

6. Precautions

Special Populations: Should be used with caution in patients with severe disturbance of consciousness.

Complicated Cases: Caution is advised in patients with subarachnoid hemorrhage complicated by severe cerebrovascular damage.

Monitoring: Close monitoring of blood pressure and heart rate during administration is recommended to detect and manage potential side effects promptly.

ECHEMI Editorial Reference

Fasudil hydrochloride, a novel calcium antagonistic vasodilator, was marketedfor the treatment of cerebral vasospasm following subarachnoid hemorrhage(SAH). Fasudil is also a potent inhibitor of myosin light chain kinase and protein kinaseC. In contrast to other calcium channel blockers, which regulate the influx of calciumions through the cell membrane but not involved in the intracellular regulatorymechanism of the calcium, fasudil was suggested to have an intracellular mode ofact
Fasudil hydrochloride is a member of isoquinolines and a N-sulfonyldiazepane.

Basic Info

Product Name:

Fasudil hydrochloride

Other Name:

Isoquinoline,5-[(hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-,hydrochloride (1:1);1H-1,4-Diazepine,hexahydro-1-(5-isoquinolinylsulfonyl)-,monohydrochloride;1-(5-Isoquinolinesulfonyl)homopiperazine hydrochloride;Eril;Fasudil hydrochloride

CAS No.:

105628-07-7

Molecular Formula:

C14H17N3O2S.ClH

InChIKeys:

InChIKey=LFVPBERIVUNMGV-UHFFFAOYSA-N

Molecular Weight:

327.83

Exact Mass:

327.081

EC Number:

1308068-626-2

UNII:

SQ04N8S7BR

DSSTox ID:

DTXSID1045615

HScode:

29339900

Categories:

Antiparkinson Agents

Characteristics

PSA:

70.7

XLogP3:

4.17030

Appearance:

white solid

Melting Point:

220 °C (approx)

Boiling Point:

506.2ºC at 760 mmHg

Flash Point:

259.9ºC

Water Solubility:

soluble in water and dimethyl sulfoxide. Insoluble in ethanol.

Toxicity:

LD50 in mice, rats (mg/kg): 67.5, 59.9 i.v.; 124.5, 123.2 s.c.; 273.9, 335.0 orally (Koga)

See More Fasudil hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Fasudil hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Company Certificates
- Certification Report by Bureau Veritas
About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

4 Inquiries

Country	Product	Purchase Quantity	Date Posted
Bulgaria	Fasudil	1 KG	Aug 16, 2025
Bulgaria	Fasudil HCL	1 KG	Aug 18, 2025
Bulgaria	Fasudil	1 KG	Jul 23, 2025
Bulgaria	Fasudil	1 KG	Aug 16, 2025

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
Fasudil hydrochloride high pure 99% raw material powder CAS 105628-07-7	Pharmaceutical Grade/99	$1/G FOB	Hubei Meisang Trading Co.,Ltd	Inquiry
Fasudil hydrochloride	/99.00		HANGZHOU LEAP CHEM CO., LTD.	Inquiry
Fasudil hydrochloride 105628-07-7	Pharmaceutical Grade/99		Hainan Flying International Trade Co., L	Inquiry
Fasudil hydrochloride,CAS105628-07-7	/		PROVCHEM	Inquiry
Get 99% pure Fasudil hydrochloride CAS 105628-07-7 for the best price	Pharmaceutical Grade/99		Xi'an Honest BioEngr Co.,Ltd.	Inquiry

Fasudil HCl

Product Details

Seller Information