CAS 910463-68-2 l Lose Weight Peptide 99% Purity Semaglutide 5mg 10mg 15mg/vial hot sale

What is Semaglutide ?  

"If you haven't heard of Semaglutide in Hollywood, you have no friends." A new type of weight loss drug is joining the ranks of traffic kings. The related tags on TikTok have been viewed more than 800 million times. Doctors are popularizing it, and everyone from Elon Musk to Internet celebrities are discussing it. It has become a drug that fashion lovers are flocking to, but experts hope that it can be used for chronic patients who need more help. At the same time, the media is also looking forward to this drug becoming the "terminator" of the global obesity problem.

Semaglutide is the newest GLP-1R agonist and was approved by the FDA as a once-weekly injection for the treatment of T2DM in late 2017. The peptide is chemically similar to liraglutide, with the inclusion of two structural modifications (Lau, Bloch, et al., 2015). The first is the replacement of Gly with the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib) at position 2. The second is the attachment of octadecanoic diacid to the side chain of Lys-26 through a short polyethylene glycol (PEG) spacer and a γ-glutamic acid linker. The amino acid substitution renders the peptide more resistant to DPP-4 compared to liraglutide, and the presence of the 18-carbon fatty acid moiety results in a high binding affinity for serum albumin, which translates to a half-life of approximately 7 days in humans.  It is used to treat type 2 diabetes and manage chronic weight. The drug functions similar to human glucagon-like peptide-1 (GLP-1) by increasing secretion, which leads to improved sugar metabolism. It is distributed as a metered subcutaneous injection in a prefilled pen, or as an oral form. One of its advantages over other antidiabetic drugs is that it has a long duration of action, thus, only once-a-week injection is sufficient.

Product Function    

• 2.Oral GLP-1RA Medication
• 3.Weight Loss
• 4.Diabetes Mellitus
• 5.Obesity
• 6.Diabetic Coma (in DM Type II)
• 7.Diabetic Ketoacidosis (in DM Type II)
• 8.Cardiovascular Risk Reduction

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