Fast weight loss Delivery Semaglutide Gip GLP-1 Injection Treatment of Obesity

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist. In clinical practice, it is often used to help improve blood glucose levels in adult patients with type 2 diabetes. Here is a detailed introduction:

• Formulations and specifications:
Injection: Semaglutide injection comes in pre-filled injection pens with various dosage options available.

• Pharmacological action: Semaglutide is a GLP-1 analogue with 94% sequence homology to human GLP-1. It selectively binds to and activates the GLP-1 receptor, promotes insulin synthesis and secretion in a glucose-dependent manner, inhibits glucagon secretion, stimulates the proliferation and differentiation of pancreatic β-cells, and inhibits cell apoptosis. Meanwhile, it can also suppress appetite and food intake, delay gastric emptying, thereby reducing the rate of postprandial blood glucose rise.

• Indications: It is suitable for adult patients with type 2 diabetes whose blood glucose is not well controlled despite diet control and exercise; it is also applicable to adult patients with type 2 diabetes accompanied by cardiovascular diseases to reduce the risk of major adverse cardiovascular events; in addition, it can be used for long-term weight management in adults, suitable for those with a BMI ≥ 30 kg/m² or a BMI between 27 kg/m² and 30 kg/m² who have at least one weight-related complication.

• Dosage: The initial injection dose is usually 0.25 mg per week. After 4 weeks, the dose can be adjusted to 0.5 mg or higher according to the patient's blood glucose level. Injections should be administered subcutaneously on a fixed day each week. Oral tablets should be taken once daily on an empty stomach, swallowed with a small amount of water, and drinking can be done 30 minutes later.

• Adverse reactions: Common adverse reactions include nausea, diarrhea, and hypoglycemia. More frequently occurring ones include gastrointestinal reactions such as loss of appetite, dizziness, complications of diabetic retinopathy, vomiting, and abdominal pain. Other possible symptoms include fatigue and elevated blood lipid levels.

• Contraindicated populations: Those allergic to the active ingredients or excipients of this product should avoid using it; individuals with a personal or family history of medullary thyroid carcinoma, or those with type 2 multiple endocrine neoplasia syndrome should avoid using it; patients with type 1 diabetes, pregnant women, and lactating women should avoid using it.

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When storing peptides, remember to:
• Store peptide in a cold, dry, dark place
• Avoid repeated freezing and thawing of peptide
• Avoid overexposure to the air
• Avoid light exposure
• Avoid storing peptides in solution long term
• Aliquot peptide according to experimental requirements

Product Specifications:

5mg/vial,10vials/box;

10mg/vial,10vials/box;

15mg/vial,10vials/box; 

20mg/vial,10vials/box;

30mg/vial,10vials/box;

60mg/vial,10vials/box

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