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ALL KINDS OF PEPTIDES"TB-500 (Thymosin B4 Acetate)" GOOD

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CAS No.:

885340-08-9

Grade:

Chemical Grade

Content:

99%

Port:

tianjin

Brand:

Packaging:

2mg*10vials 5mg*10vials 10mg*10vials

Price valid (until):

2025-09-22

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NBHH Technology for Pharmaceutical Inte

Company Type:

Trader

Location:

China

Qualification:

Main Products:

S3,14 bd0

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Product Description
Seller Information
Inquiry History

Description

Product Detail

What is TB-500 (Thymosin Beta-4 Acetate)?WHATSAPP:+86 181 0218 6421

TB-500, chemically known as Thymosin Beta-4 Acetate, is a synthetic peptide derived from the naturally occurring human protein Thymosin Beta-4 (Tβ4). It is primarily recognized for its potential roles in tissue repair and regeneration.

Core Information & Key Details

Category	Specific Explanations
Basic Properties	- A linear peptide composed of 43 amino acids. - The "acetate" form refers to its salt form, which often improves stability and solubility compared to the non-acetylated version. - Naturally, Thymosin Beta-4 is widely present in human tissues (e.g., blood, muscles, and organs) and plays a role in cell migration and wound healing.
Mechanism of Action	Its key effects are mainly mediated by regulating cell behavior and tissue microenvironment: 1. Promotes the migration of repair-related cells (e.g., fibroblasts, endothelial cells) to damaged tissues. 2. Stimulates the formation of new blood vessels (neovascularization) to supply nutrients to injured areas. 3. Modulates inflammatory responses to reduce excessive inflammation and support tissue recovery. 4. May assist in the reorganization of cytoskeletons, facilitating cell growth and tissue regeneration.
Potential Effects	- Tissue Repair: Focused on repairing injuries to muscles, tendons, ligaments, and skin (e.g., accelerating the healing of sports-related tendon strains or muscle tears). - Skin Health: May support wound healing (e.g., for cuts, burns) and help reduce scarring by regulating collagen deposition. - Ocular Support: In preclinical studies, it has shown potential in repairing damaged ocular tissues (e.g., corneal injuries), but this requires further clinical validation.
Administration & Storage	- Common Forms: Currently, it is mainly available as a lyophilized (freeze-dried) powder, which needs to be reconstituted with a solvent (e.g., sterile water or saline) before use; administration routes often include subcutaneous injection or local injection at the injury site. - Storage Conditions: Unreconstituted lyophilized powder should be stored at below -20°C in a dry environment. After reconstitution, it should be stored at 2–8°C and used within a short period (usually 1–3 days) to avoid degradation; repeated freeze-thaw cycles must be avoided.
Important Notes	- Research Stage: Most of its effects are based on preclinical studies (cell or animal experiments); clinical evidence in humans is still limited, and its safety and efficacy for various indications have not been fully verified by mainstream regulatory authorities (e.g., FDA). - Safety Risks: Potential risks (e.g., local injection site reactions, allergic responses) cannot be excluded; it should not be used without professional guidance. - Regulatory Status: It is not approved as a therapeutic drug in most countries/regions and is primarily used for research purposes.

ECHEMI Editorial Reference

TB 500 is a synthetically made version of TB4 that facilitates healing and recovery by helping build new blood vessels, muscle tissue fibers, blood cells, and facilitating cell migration. It acts on the muscular system and has anabolic properties. TB 500 is used primarily for race animals (horses and dogs).

Basic Info

Product Name:

TB500

Other Name:

TB500 fragment;L-Glutamine, N-acetyl-L-leucyl-L-lysyl-L-lysyl-L-threonyl-L-α-glutamyl-L-threonyl-;Thymosin Beta 4 Peptide Peptides Tb500 2mg/Vials 5mg/Vials;TB500 fragment acetate;TB500 Thymosin Beta 4 (TB4);Ac-LKKTETQ;Thymosin β4 TB500;TB500(Thymosin B4 AceTate) 5MG 10MG

CAS No.:

885340-08-9

Molecular Formula:

C38H68N10O14

InChIKeys:

ADKDNDYYIZUVCZ-HLXZCORBNA-N

Molecular Weight:

889.02

EC Number:

232-660-2

Color/Form:

White to Off-White

Categories:

Polypeptide

Characteristics

Density:

1.281±0.06 g/cm3(Predicted)

Boiling Point:

1405.0±65.0 °C(Predicted)

PKA:

3.20±0.10(Predicted)

Research

Class:

Actin-sequestering protein / 43-amino-acid peptide

Status:

Research compound — Not FDA approved (investigational: RGN-259 for dry eye / neurotrophic keratitis)

Mechanism:

A naturally occurring 43-amino-acid peptide (Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH) that binds G-actin (sequesters monomeric actin), preventing F-actin polymerization. Promotes cell migration, angiogenesis, wound healing, and anti-inflammatory responses via integrin-linked kinase (ILK) and HIF-1α/VEGF pathways. TB-500 is the synthetic fragment Ac-LKKTETQ (MW ~895) often sold under this CAS.

Activity note:

Thymosin Beta-4 is an actin-binding protein, not a receptor agonist. Functional activity is measured by actin sequestration (Kd ~0.7–1 μM) and cell migration assays, not EC₅₀.

Source:

Goldstein AL, et al. Vitam Horm. 2003;66:257–296. RegeneRx RGN-259 clinical program.DOI

Clinical Development:

NCT02974907; NCT02600429; NCT00376974

References

DrugBank:

DB04951

PubChem:

PubChem

UNII:

549LM7U24W

Literature:

PubMed: Goldstein AL et al. (2003) — Review; ClinicalTrials.gov: ARISE-1 (NCT02974907)

Disclaimer:

Thymosin Beta-4 (TB-500) is NOT FDA-approved for human therapeutic use. RGN-259 (Tβ4 ophthalmic solution) is an investigational drug not yet approved. TB-500 sold on research-chemical marketplaces is a synthetic fragment and is not an approved medicine. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

Seller Information

Business Type:
Trader

Main Products:
S3,14 bd0

Location:
Room8-18,building156,No.19,26,27,QinglinCommercial Plaza,Haishu District,Ningbo City,Zhejiang Province

Payment Terms:
TT against copy of documents,L/C,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
Less than $1 million

Total Employees:
11-50

Year of Establishment:
2020

Ningbo Henghua Technology Development Co., Ltd. is a company specialized in export. Our main products include pharmaceutical intermediates, food additives, chemical products, and cosmetic raw materials. These products are exported to over 80 countries and regions, including North America, Europe, Singapore, Australia, Russia, Africa, the Middle East, and more. Additionally, we offer product customization services to meet the specific needs of our clients. With a global customer base, we are able to provide the best product quality at competitive prices.

To further meet customer demands and offer "door-to-door" services, we have established our own export service system. This allows us to provide clients with optimal export routes at the lowest possible prices.

Moreover, we have a top-tier R&D team, a professional production team, and a strict quality control department, enabling us to offer overseas clients the best goods at the lowest prices, inspect products, and reserve shipping spaces, thus facilitating the expansion of the Chinese market and eliminating concerns regarding import and export. We also provide patient and attentive after-sales service to assist with any issues during the order process.

By choosing henghua, you will have a reliable partner, high-quality products, fast and secure transportation, and worry-free after-sales support. Our mission is to "earn your trust and support through service and sincerity, achieving mutual benefit and win-win outcomes." We adhere to the management principles of "Quality First, Service First, Continuous Improvement, and Innovation to Satisfy Customers," with a quality goal of "Zero Defects, Zero Complaints." Henghua Technology looks forward to cooperating with friends from all over the world!

Inquiry History

35 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Factory price CAS 885340-08-9 L-Glutamine TB500	1 KG	Sep 26, 2023
United States	TB500 99% White powder Beta-4 CAS 885340-08-9 powder Custom peptides	1000	Oct 30, 2023
United States	TB 500	150 MG	Apr 8, 2026
United States	China Origin TB500 2mg/5mg/10mg Lyophilized Powder for the Wound Repair Research	1 G	Mar 26, 2026
United States	TB500	100 MG	Feb 27, 2026
Germany	TB 500	1 KG	Feb 8, 2026
Portugal	Tb 500	10 MT	Aug 7, 2024
France	TB500	1 KG	Mar 27, 2024
United States	TB500	1 G	Jan 27, 2024
Brazil	TB-500	1 G	Jun 18, 2026
Canada	TB 500	1 KG	May 8, 2026
United States	TB 500	20 G	Feb 23, 2026
Brazil	alejandro	300 PCS	Feb 19, 2026
United States	TB500 10mg	1 MT	Oct 20, 2025
United States	Tesomorelin	1 KG	Aug 8, 2025
Italy	TB500	1000 MG	Dec 30, 2024
Netherlands	tb500	1	Dec 16, 2024
New Zealand	TB500	100 MG	Jun 24, 2024
Germany	High Purity 99% Tb-500 5mg TB 500 Peptide TB500	1 MT	Oct 19, 2023
United States	High Purity 99% Tb-500 5mg TB 500 Peptide TB500	10 MT	Oct 12, 2023

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ALL KINDS OF PEPTIDES"TB-500 (Thymosin B4 Acetate)" GOOD

Product Description

Seller Information

Inquiry History

What is TB-500 (Thymosin Beta-4 Acetate)?WHATSAPP:+86 181 0218 6421

Core Information & Key Details

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