PNC-27-Fast delivery PNC-27 Raw Materials CAS: 1159861-00-3 99% purity affordable price powder factory direct sale
TDS 3 Inquiries
1159861-00-3
Pharmaceutical Grade
99%
SHENZHEN
APKX
5 mg/vial 10 mg/vial
2027-02-01
peptides
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferencePNC-27 is an anti-cancer peptide that, in small in-vitro studies, has been shown to induce tumour cell necrosis. It is not currently approved for use in the United States (U.S.) and is currently being marketed online as a non-toxic potential cure for various cancers. Recently, the FDA issued warnings to the public regarding PNC-27 use, suggesting possible contamination and unknown side effects of the treatment. PNC-27 may be available in various dosage forms, such as a nebulized solution, intravenous solution, vaginal suppository, or rectal suppository. FDA has not evaluated or approved PNC-27 as safe and effective in treating any disease, including cancer[1].
PNC-27 is an anticancer peptide, containing an HDM-2-binding domain. PNC-27 shows anti-tumor activity and can be used in acute myeloid leukemia research.CertificatesBasic Info-
Product Name:
PNC-27
Other Name:PNC27
CAS No.:1159861-00-3
Molecular Weight:0
Categories:
Research-
Class:
Actin-sequestering protein / 43-amino-acid peptide
Status:Research compound — Not FDA approved (investigational: RGN-259 for dry eye / neurotrophic keratitis)
Mechanism:A naturally occurring 43-amino-acid peptide (Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH) that binds G-actin (sequesters monomeric actin), preventing F-actin polymerization. Promotes cell migration, angiogenesis, wound healing, and anti-inflammatory responses via integrin-linked kinase (ILK) and HIF-1α/VEGF pathways. TB-500 is the synthetic fragment Ac-LKKTETQ (MW ~895) often sold under this CAS.
Activity note:Thymosin Beta-4 is an actin-binding protein, not a receptor agonist. Functional activity is measured by actin sequestration (Kd ~0.7–1 μM) and cell migration assays, not EC₅₀.
Source:Goldstein AL, et al. Vitam Horm. 2003;66:257–296. RegeneRx RGN-259 clinical program.DOI
Clinical Development:
References-
DrugBank:PubChem:UNII:Disclaimer:
Thymosin Beta-4 (TB-500) is NOT FDA-approved for human therapeutic use. RGN-259 (Tβ4 ophthalmic solution) is an investigational drug not yet approved. TB-500 sold on research-chemical marketplaces is a synthetic fragment and is not an approved medicine. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
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Seller Information
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Business Type:
Trader
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Main Products:
peptides
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Location:
Room 3043, 3rd Floor, Building 15, No. 185 Xinda Road, Wanghailou Street, Hebei District, Tianjin
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2025
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Certifications:
.,证书
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Inquiry History3 Inquiries
Country Product Purchase Quantity Date Posted 
United States
PNC27
10 PCS Apr 11, 2026
United States
PNC-27
1 PCS Sep 4, 2026
United States
PNC-27
5 MG Sep 4, 2026 Post an enquiry for this product
