Valbenazine RC05880
1 Inquiries
1025504-45-3
Pharmaceutical Grade
25kg/drum
2030-01-01
Pharmaceutical intermediates
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceValbenazine (development name NBI-98854) has been used in trials studying the treatment and basic science of Tourette Syndrome and Tardive Dyskinesia. In April, 2017, valbenazine was approved by the FDA (as Ingrezza) as the first and only approved treatment for adults with Tardive Dyskinesia (TD).|Valbenazine is a Vesicular Monoamine Transporter 2 Inhibitor. The mechanism of action of valbenazine is as a Vesicular Monoamine Transporter 2 Inhibitor.|The vesicular monoamine transporter type 2 (VMAT2) inhibitors are agents that cause a depletion of neuroactive peptides such as dopamine in nerve terminals and are used to treat chorea due to neurodegenerative diseases (such as Huntington chorea) or dyskinesias due to neuroleptic medications (tardive dyskinesia). As of 2019, three VMAT2 inhibitors have become available in the United States for management of dyskinesia syndromes, each with a somewhat different spectrum of approved indications: tetrabenazine (Xenazine and generics: 2008), deutetrabenazine (Austedo: 2017) and valbenazine (Ingressa: 2017). The VMAT2 inihibitors have not been associated with serum enzyme elevations during therapy or linked to instances of clinically apparent liver injury, but they have had limited general clinical use.Basic Info
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Product Name:
Valbenazine
Other Name:Valbenazine;CS-2484;Valbenazine Free base;NBI-98854; NBI 98854; NBI98854; VALBENAZINE;[(2R,3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-yl] (2S)-2-amino-3-methylbutanoate;Valbenazine(NBI-98854);(S)-2-amino-3 -methylbutyric acid(2R,3R,11bR)-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-yl ester;Tetrabenazine Related Impurity 28
CAS No.:1025504-45-3
Molecular Formula:C24H38N2O4
InChIKeys:GEJDGVNQKABXKG-CFKGEZKQSA-N
Molecular Weight:418.57
Exact Mass:418.57
UNII:54K37P50KH
Color/Form:Light Yellow to Yellow
ATC Code:N - Nervous system
Categories:
Characteristics-
Density:
1.11±0.1 g/cm3(Predicted)
Melting Point:>75°C (dec.)
Boiling Point:507.2±50.0 °C(Predicted)
PKA:7.76±0.33(Predicted)
Critical Temperature & Pressure:Hygroscopic, -20°C Freezer, Under inert atmosphere
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
Pakistan
Valbenazine
1 KG May 15, 2025 Post an enquiry for this product