L-Histidine RC03635
13 Inquiries
71-00-1
Pharmaceutical Grade
99%
Royalchem
25kg/drum
2030-01-01
Pharmaceutical intermediates
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceWhite crystalline or crystalline powder,odorless,slightly bitter taste. Melting and decomposition at about 277~288 ℃. The imidazole and metal ions are easy to form complex salt. Dissolve in water (4.3g/100ml, 25 ℃), very difficult to dissolve in ethanol, insoluble in ether.
It is commonly used for its hydrochloride, because of minimal solubility and other reasons.
Solid|White crystals or crystalline powder; odourless
L-histidine is the L-enantiomer of the amino acid histidine. It has a role as a nutraceutical, a micronutrient, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite, an algal metabolite and a mouse metabolite. It is a proteinogenic amino acid, a histidine and a L-alpha-amino acid. It is a conjugate base of a L-histidinium(1+). It is a conjugate acid of a L-histidinate(1-). It is an enantiomer of a D-histidine. It is a tautomer of a L-histidine zwitterion.|An essential amino acid that is required for the production of histamine.|Histidine is a semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, Histidine is important for maintenance of myelin sheaths that protect nerve cells and is metabolized to the neurotransmitter histamine. Histamines play many roles in immunity, gastric secretion, and sexual functions. Histidine is also required for blood cell manufacture and protects tissues against damage caused by radiation and heavy metals. (NCI04)|An essential amino acid that is required for the production of HISTAMINE.Basic Info-
Product Name:
L-Histidine
Other Name:L-Histidine;Histidine,L-;Histidine;1H-Imidazole-4-propanoic acid,α-amino-,(S)-;(S)-4-(2-Amino-2-carboxyethyl)imidazole;Glyoxaline-5-alanine;L-(-)-Histidine;(S)-Histidine;(S)-α-Amino-1H-imidazole-4-propanoic acid;1H-Imidazole-4-alanine,(S)-;L-Alanine,3-(1H-imidazol-4-yl)-;NSC 137773;(2S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid;8: PN: EP2878667 TABLE: 5 claimed sequence;(S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid;(2S)-2-Azaniumyl-3-(1H-imidazol-5-yl)propanoate;(2S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid;124: PN: WO2020191245 SEQID: 252 claimed protein;103: PN: WO2021061872 SEQID: 103 claimed protein;150-35-6;7006-35-1;35479-49-3;35558-59-9;45955-20-2;54166-13-1;736075-03-9;155304-24-8
CAS No.:71-00-1
Molecular Formula:C6H9N3O2
InChIKeys:InChIKey=HNDVDQJCIGZPNO-YFKPBYRVSA-N
Molecular Weight:155.15
Exact Mass:155.15
BRN:4673585
EC Number:200-745-3
UNII:4QD397987E
DSSTox ID:DTXSID9023126
NCI Thesaurus Code:C29597
Color/Form:Needles or plates|COLORLESS
HScode:29332990
Categories:
Characteristics-
PSA:
92
XLogP3:-3.2
Appearance:White to off-white or pale yellow powder
Density:1.3092 (rough estimate)
Melting Point:287 °C (decomp)
Boiling Point:278.95°C (rough estimate)
Flash Point:282ºC
Refractive Index:1.731
Water Solubility:H2O: 41.6 g/L (25 ºC)
Storage Conditions:Store at RT.
Toxicity:LD50 orally in Rabbit: > 5110 mg/kg
Specific rotation:12.4 º (c=11,6N HCl)
Taste:Sweet
PKA:2.76(at 0 °C)
Dissociation Constants:2.76 (at 0 °C)|pK1'= 1.78; pK2'= 5.97; pK3'= 8.97|pKa = 2.76 @ 0 °C
Collision Cross Section:131.9 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|132.41 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|131.47 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|127 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|131.7 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|132.1 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|134.6 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|134.8 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|128.1 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|128.5 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|130.01 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|132.74 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|135.48 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|128.9 Ų [M-H]-
Experimental Properties:Softens @ 277 °C|Rhombic crystals (also forms a monohydrate) /L-histidine monohydrochloride/; rhombic crystals, isomorphous with the mono-HCl /L-histidine dihydrochloride/|UV: 11479 (Sadtler Research Laboratories Spectral Collection) /dl-Histidine/
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Inquiry History13 Inquiries
Country Product Purchase Quantity Date Posted 
Egypt
L- Histidine
1.00 KG Apr 29, 2026 
India
L-Histidine
25.00 KG Aug 28, 2026 
Bangladesh
L-Histidine
50.00 KG Jul 30, 2026
India
L-Histidine
1 MT Apr 23, 2025
India
L-Histidine
100.00 KG Sep 7, 2026
India
L-Histidine
300.00 KG Sep 4, 2026
India
L-Histidine
1 G Jan 14, 2026 
Slovenia
L-HISTIDINE
400 KG Jan 9, 2026 
Greece
HISTIDINE (His, H)
700.00 KG Sep 24, 2025
Egypt
L-Histidine
250 KG Apr 22, 2024
Egypt
L-Threonine
100.00 KG Aug 20, 2026
Egypt
carbo cysteine
100.00 KG Jun 22, 2026
Bangladesh
Butyl Acetate
1.00 KG Nov 11, 2025 Post an enquiry for this product
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