99% USP Standard Cilostazol High Quality

Cilostazol More Info

Cilostazol is a synthetic quinolinone derivative specifically developed as a vasodilating and antiplatelet agent. Its primary mechanism of action is the selective inhibition of phosphodiesterase type III (PDE3), an enzyme that breaks down cyclic adenosine monophosphate (cAMP). By inhibiting PDE3, cilostazol increases intracellular cAMP levels in platelets and vascular smooth muscle cells. This elevated cAMP concentration leads to the inhibition of platelet aggregation and causes vasodilation, particularly in peripheral arteries. It was developed as a therapeutic alternative to provide a different mode of action compared to other antiplatelet medications like aspirin or clopidogrel, offering a unique combination of effects beneficial for specific vascular conditions.

Uses and Applications

The primary and approved medical application of cilostazol is for the symptomatic management of intermittent claudication, a condition characterized by pain in the legs during walking due to reduced blood flow from peripheral artery disease. It is indicated to improve pain-free walking distance and overall mobility in affected patients. Beyond this core use, it is also utilized in some regions for the prevention of recurrent cerebral infarction (stroke) due to its anti-thrombotic properties. Its application is strictly pharmaceutical, and it is formulated into oral solid dosage forms, typically tablets, under strict quality control standards for prescription use.

Application Market

The market for cilostazol is a well-defined segment within the global cardiovascular pharmaceutical market. It is an established, prescription-only drug facing competition from both other pharmaceutical interventions and non-pharmacological treatments for peripheral artery disease. The market is dominated by branded formulations and, increasingly, generic versions following patent expiration, making it more accessible. Demand is driven by the global prevalence of peripheral artery disease, particularly in aging populations in North America, Europe, and Asia. Distribution is tightly controlled through pharmaceutical supply chains to pharmacies and hospitals, and its market performance is closely tied to clinical guidelines that recommend its use for specific patient populations.

Important Considerations

Cilostazol is a potent prescription medication with significant contraindications and requires careful medical supervision. It is strictly contraindicated in patients with heart failure of any severity due to the potential risk of increased mortality associated with PDE3 inhibitors. Common adverse effects include headache, diarrhea, palpitations, and dizziness. Its use requires a thorough benefit-risk assessment by a healthcare professional, considering the patient's complete medical history and concomitant medications, especially other antiplatelet or anticoagulant drugs that may increase bleeding risk. In industrial settings, handling the pure active pharmaceutical ingredient mandates the use of appropriate engineering controls and personal protective equipment to prevent occupational exposure through inhalation or skin contact. It is not for consumer handling and must be administered in its final, prescribed dosage form.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

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Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.