Methylparaben CAS 99-76-3
COA 10 Inquiries
99-76-3
99%
Believe
25kg/drum
2025-10-22
(R)-3-hydroxypyrrolidine hydrochloride,(R)-Glycidyl butyrate,fine chemicals,2-dibromo-4,5-difluorobenzene,(S)-(+)-Mandelic acid
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceMethyl Paraben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen. Methyl Paraben is a stable, non-volatile compound used as an antimicrobial preservative in foods, drugs and cosmetics. The physiologic effect of Methyl Paraben is by means of increased histamine release, and cell-mediated immunity[1].
Methylparaben occurs as colorless crystals or a white crystalline powder. It is odorless or almost odorless and has a slight burning taste. Soluble in alcohol,ether; slightly soluble in water, benzene, and carbontetrachloride.
ChEBI: Methylparaben is a 4-hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol. It is the most frequently used antimicrobial preservative in cosmetics. It occurs naturally in several fruits, particularly in blueberries. It has a role as a plant metabolite, an antimicrobial food preservative, a neuroprotective agent and an antifungal agent.
The carcinogenic potential of methyl paraben has been studied in rodents. Several studies are available, but none that expose animals via oral or dermal routes. No evidence of a carcinogenic effect was observed following intravenous or subcutaneous injection .
Fractionally crystallise the ester from its melt, and recrystallise it from *benzene, then from *benzene/MeOH and dry it over CaCl2 in a vacuum desiccator. [Beilstein 10 IV 360.]CertificatesBasic Info-
Product Name:
Methylparaben
Other Name:NIPAGIN PLAIN;P-HYDROXYBENZOIC ACID METHYL ESTER;RARECHEM AL BF 0098;METHYLPARABEN,FCC;METHYLPARABEN,NF;4-HYDROXYBENZOICACIDMETHYLESTER(METHYLPARABEN);4-HYDROXYLMETHYLBENZOATE;Methyl-4-hydroxybenzoat
CAS No.:99-76-3
Molecular Formula:C8H8O3
InChIKeys:LXCFILQKKLGQFO-UHFFFAOYSA-N
Molecular Weight:152.15
Exact Mass:152.15
BRN:509801
EC Number:202-785-7
TSCA:TSCA listed
Color/Form:White to almost white
HScode:29182930
Categories:
Characteristics-
PSA:
46.5
XLogP3:2
Appearance:White to almost white Crystalline Powder
Density:1,46g/cm
Melting Point:125-128 °C (lit.)
Boiling Point:298.6 °C
Flash Point:280°C
Refractive Index:1.4447 (estimate)
Water Solubility:Slightly soluble in water.
Storage Conditions:0-6°C
Vapor Pressure:0.000005 hPa (20 °C)
Toxicity:ADI 0～10mg/kg(FAO/WHO,2001).GRAS(FDA,§184．1490，2000).LD503000mg/kg(Dog, mouth)
Flammability characteristics:Flammable, spicy and irritating smoke emitted from the fire
Odor:odorless or faint char. odor, sl. burning taste
PH:5.8 (H2O, 20°C) (saturated solution)
PKA:pKa 8.15(H2O,t =20.0) (Uncertain)
Henrys Law Constant:4.5×103mol/(m3Pa) at 25℃, HSDB (2015)
Autoignition Temperature:>600 °C
Critical Temperature & Pressure:room temp
Hazard IdentificationClassification of the substance or mixture
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word No signal word
Hazard statement(s) H411 Toxic to aquatic life with long lasting effects
Precautionary statement(s) Prevention P273 Avoid release to the environment.
Response P391 Collect spillage.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place.
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Seller Information
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Business Type:
Distributor
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Main Products:
(R)-3-hydroxypyrrolidine hydrochloride,(R)-Glycidyl butyrate,fine chemicals,2-dibromo-4,5-difluorobenzene,(S)-(+)-Mandelic acid
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Location:
Room 2231, Zhigu Industrial Park, Building 1, North of East Planning Road, East Gaoxin 2nd Road, Weifang Comprehensive Bonded Zone, Shandong Province
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
101-200
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Year of Establishment:
2020
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Certifications:
SGS,ISO
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Inquiry History10 Inquiries
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