 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Leucovorin for Sale > leucovorin 58-05-9

leucovorin 58-05-9

Name: leucovorin 58-05-9
Brand: BELIEVE
SKU: pr2509231332
Price: 10 USD
Availability: InStock

5 Inquiries

Unit Price: Get Latest Price 

CAS No.:

58-05-9

Content:

99%

Port:

shanghai

Brand:

BELIEVE

Packaging:

25kg

Price valid (until):

2025-10-23

Contact Supplier

 Chat Now

Shan Dong Believe Chemical Pte. Ltd.

Company Type:

Distributor

Location:

China

Qualification:

Main Products:

(R)-3-hydroxypyrrolidine hydrochloride,(R)-Glycidyl butyrate,fine chemicals,2-dibromo-4,5-difluorobenzene,(S)-(+)-Mandelic acid

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Product Detail

Folic acid (calcium folinate) is a special form of reduced folate, and high-dose folic acid intervention given to children with CFD can improve their neurological and developmental abnormalities. Abnormal folate metabolism is associated with the occurrence of autism in children. The genetic polymorphism of folate related pathways may lead to abnormal folate metabolism. Research has found that supplementing folic acid during prenatal and pregnancy periods can reduce the risk of autism in offspring. The application of L-folinic acid as an anti-tumor detoxifier and an adjuvant drug against megaloblastic anemia, with a dose of 1/2 of folic acid. L-folinic acid does not need to be reduced by dihydrofolate reductase to participate in reactions using folate as a source of one carbon unit, and it can actively or passively pass through the cell membrane; The basic function of L-folinic acid is the same as folic acid, but its effect is better than folic acid. At the same time, L-folinic acid also has the effect of stimulating the growth and maturation of white blood cells, which can improve megaloblastic anemia.

Company Detail

Shandong Believe Chemical Pte. Ltd, is a high-tech enterprise specializing in the R&D, production, and sales of pharmaceutical intermediates, fine chemicals, electronic material intermediates, and dye intermediates. Based in one of China’s key chemical industry hubs, the company leverages strong technical expertise, stringent quality control systems, and comprehensive customer service to become a trusted supplier for global partners in related sectors.

Core Business Areas

Pharmaceutical Intermediates

Supplies high-purity, advanced intermediates such as fluorobenzene, boronic acid, and heterocyclic compounds, tailored for innovative and generic drug synthesis.

Fine Chemicals

Provides customized fine chemicals for catalysts, surfactants, and specialty additives to meet precise industrial process requirements.

Electronic Material Intermediates

Offers critical high-purity intermediates (e.g., fluorine/sulfur-containing compounds) for semiconductors, LCDs, photoresists, and new energy battery materials.

Dye Intermediates

Manufactures key intermediates for high-performance, eco-friendly dyes and pigments, ensuring vibrant color and consistent quality.

Our Strengths

R&D-Driven Innovation: A dedicated team and advanced laboratory enable continuous process optimization and custom synthesis capabilities.

Stringent Quality Assurance: Full-process quality control from raw materials to finished products ensures high purity, consistency, and reliability.

Integrated Production Capacity: Modern facilities support seamless scaling from pilot to large-scale production, guaranteeing stable supply.

Customer-Centric Approach: Competitive pricing, flexible supply chain solutions, and professional technical support foster long-term partnerships.

Vision & Values

Guided by the principles of Innovation, Quality, and Responsibility, Shandong Billy Fluorine Chemical aims to deliver superior chemical products and services worldwide, positioning itself as a leader in the fine chemical industry.

For inquiries and collaboration, we welcome you to reach out. Let’s create success together.

Basic Info

Product Name:

Leucovorin

Other Name:

L-Glutamic acid,N-[4-[[(2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-;Glutamic acid,N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-,L-;L-Glutamic acid,N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-;N-[4-[[(2-Amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid;Folinic acid;N5-Formyl-5,6,7,8-tetrahydrofolic acid;5-Formyl-5,6,7,8-tetrahydrofolic acid;N5-Formyltetrahydrofolic acid;Leucovorin;5-Formyltetrahydropteroylglutamic acid;Folinic acid-SF;Leucal;5-Formyltetrahydrofolic acid;l-Leucovorin;Welcovorin;Leucoverin;CF;(6R,S)-5-Formyltetrahydrofolate;Kunyrin;N5-Formyl-THF;121521-95-7;641-41-8;3102-53-2;17435-36-8;33299-78-4;34786-59-9;40244-99-3

CAS No.:

58-05-9

Molecular Formula:

C20H23N7O7

InChIKeys:

InChIKey=VVIAGPKUTFNRDU-ABLWVSNPSA-N

Molecular Weight:

473.44

Exact Mass:

473.44

EC Number:

200-361-6

DSSTox ID:

DTXSID3036999|DTXSID0048216

Color/Form:

Crystals from water with 3 mol of water of crystallization.

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

219.84000

XLogP3:

1.15290

Density:

1.68g/cm3

Melting Point:

245 °C (decomp)

Refractive Index:

1.748

Water Solubility:

>1350g/L(25 ºC)

Vapor Pressure:

2.3X10-21 mm Hg at 25 °C at 25 °C /Estimated/

Specific rotation:

D20 +14.26° (c = 3.42 as anhydr Ca salt)

PH:

pH of saturated solution in water = 2.8-3.0.

Henrys Law Constant:

Henry's Law constant = 4.4X10-27 atm-cu m/mole at 25 °C /Estimated/

Dissociation Constants:

pKa1= 3.1; pKa2= 4.8; pKa3= 10.4

Experimental Properties:

Crystals; decompose 240-250 °C; sparingly soluble in water. /dl-Folinic acid/|Hydroxyl radical reaction rate constant = 2.7X10-10 cu cm/molec-sec at 25 °C /Estimated/

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Leucovorin Safety Data Sheet 

Seller Information

Business Type:
Distributor

Main Products:
(R)-3-hydroxypyrrolidine hydrochloride,(R)-Glycidyl butyrate,fine chemicals,2-dibromo-4,5-difluorobenzene,(S)-(+)-Mandelic acid

Location:
ROOM 574 JIUDINGFENG LARGE BUILDING NO.888 CHANGBAISHAN ROAD QINGDAO AREA CHINA (SHANDONG) PILOT FREE TRADE ZONE

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
101-200

Year of Establishment:
2020

Certifications:
ISO,SGS

Inquiry History

5 Inquiries

Country	Product	Purchase Quantity	Date Posted
Qatar	folinic acid	1 KG	Feb 27, 2024
Netherlands	Folinic acid	5 KG	Mar 18, 2026
United States	leucovorin	10 MG	Sep 23, 2025
Latvia	Folinic acid	1 20' Fcl	Mar 4, 2026
Australia	Leucovorin	1 KG	Oct 21, 2025

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
Leucovorin, CAS:58-05-9	Reagent Grade/99	$12-13/KG FOB	Guangzhou Yaoguang Technology Co., Ltd.	Inquiry
Factory Supply Folinic Acid CAS 58-05-9	/		Shandong zhishang chemical Co.,Ltd	Inquiry
Folinic Acid Raw Material (ISO Approved \| Fast Delivery)	Pharmaceutical Grade/99		Hangzhou Hyper Chemicals Limited	Inquiry
5-formyl-5,6,7,8-tetrahydrofolate	/		SHANDONG LOOK CHEMICAL CO.,LTD	Inquiry
Folinic acid	/99.00		HANGZHOU LEAP CHEM CO., LTD.	Inquiry