delta-Valerolactone cas 542-28-9 colorless lqiuid support customized

δ-Pentyl lactone, abbreviated as DVL, is a colorless to pale yellow oily liquid with a boiling point of 218℃ (at normal pressure) and a flash point of 107℃. It is a versatile fine chemical intermediate and is widely used in pharmaceutical intermediates, flavor and fragrance, polyesters, polyurethanes, special solvents, coatings, and other fields.   Delta-pentyl lactone is an organic synthesis intermediate and a pharmaceutical research intermediate. It can be used in laboratory organic research processes and chemical and pharmaceutical synthesis processes.  

The most common name for this substance is α,α-dichlorotoluene. It is a relatively important organic synthetic intermediate in both industry and laboratories.
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1. Basic Information

· Chinese name: α,α-Dichlorotoluene; Benzyl dichloride; Dichloromethylbenzene
· English name: α,α-Dichlorotoluene; (Dichloromethyl)benzene; Benzyl dichloride
· CAS Number: 542-28-9
· Molecular Formula: C₇H₆Cl₂
· Structural Formula: C₆H₅-CHCl₂
· Molecular Weight: 161.03 g/mol
2. Physical and Chemical Properties
· Appearance: Usually a colorless or pale yellow liquid with a strong pungent odor.
· Boiling point: Approximately 205 - 208 °C
· Density: Approximately 1.26 g/cm³ (denser than water)
· Solubility: Does not dissolve in water, but can mix with most organic solvents (such as ethanol, ether, benzene).
· Chemical properties: Highly reactive. The two chlorine atoms in the molecule are connected to the same carbon atom, making this carbon atom highly electron-deficient and prone to being attacked by nucleophilic reagents. Therefore, it is very easy to undergo hydrolysis, alcoholysis, and amide (amine) hydrolysis and other reactions.
3. Main purposes
α,α-Dichlorotoluene is mainly used as a key intermediate in organic synthesis, and is employed for the production of various fine chemicals:
1. Production of benzaldehyde: This is one of its most important industrial applications. It can be efficiently converted into benzaldehyde through acid hydrolysis or by reacting with urotropine (the Sommelet reaction). \ce{C6H5CHCl2 + H2O -> C6H5CHO + 2HCl}
2. Synthesis of benzoic acid and its derivatives: Through further oxidation, benzoic acid can be prepared.
3. Synthesis of nitrogen-containing compounds:
· Reacting with ammonia or amines can produce benzoimide amides or their derivatives.
· It is used for synthesizing isonitriles (when reacting with AgCN).
4. Synthesis of other functional group compounds:
· Can react with sodium thiol to form sulfides.
· Under specific conditions, it can be converted into benzonitrile.
4. Safety and Hazards
This is a highly dangerous chemical that requires extreme caution.
· Corrosiveness: It has strong irritancy and corrosiveness to the skin, eyes and respiratory mucous membranes.
· Irritant: Its vapor has a strong irritating effect.
· Toxicity: It is toxic. Inhalation, ingestion or absorption through the skin can cause harm to the body. During metabolism or hydrolysis, it releases hydrogen chloride (HCl), causing internal damage.
· Stability: Unstable. It will slowly hydrolyze when exposed to water or humid air, releasing corrosive hydrogen chloride gas.
· Environmental hazard: It is toxic to aquatic organisms.
Safety Operating Precautions:
· The operation must be carried out in a well-ventilated area (such as a fume hood).
· Wear appropriate personal protective equipment, including chemical protective gloves, splash-proof goggles and protective clothing.
· Avoid contact with skin and eyes, and avoid inhaling its vapors.
· Store in a cool, dry and well-ventilated place, and keep the container sealed.
5. Relevant compounds
To better understand it, it is usually compared with its two "siblings":
· Benzyl chloride (CAS: 100-44-7): C₆H₅-CH₂Cl
· It has moderate activity and is the most common benzylating reagent among these three.
· α,α-Dichlorotoluene (CAS: 542-28-9): C₆H₅-CHCl₂
· It has high activity and is mainly used to introduce functional groups such as aldehyde groups into molecules.
· Benzyl trichloride (CAS: 98-07-7): C₆H₅-CCl₃
· It has the highest activity and is mainly used for synthesizing benzoyl chloride (C₆H₅-COCl) and trifluoromethylbenzene (C₆H₅-CF₃).
Summary
CAS 542-28-9 (α,α-Dichlorotoluene) is a highly reactive organic halide. It plays a crucial role as an intermediate in organic synthesis, particularly in the preparation of benzaldehyde and its derivatives. However, due to its strong irritancy, corrosiveness and toxicity, strict safety protocols must be followed during storage, transportation and usage.