99% High Purity Raw Power Creatinine With USP Pharmacy Grade in Stock Fast Delivery

Creatinine More Info

Creatinine is a biological waste product formed from the non-enzymatic dehydration of creatine in muscle tissue. This compound is generated at a relatively constant rate in the body, proportional to muscle mass, and is primarily eliminated by renal filtration. First identified in the 19th century, creatinine's consistent production and clearance mechanisms make it a crucial indicator for assessing kidney function. The molecule's simple structure—a cyclic derivative of creatine—contributes to its stability in biological fluids. Its reliable generation and elimination kinetics have established it as one of the most important biomarkers in clinical chemistry, with laboratory measurement methods evolving from early colorimetric techniques to modern automated enzymatic and chromatographic assays.

Uses and Applications

The primary application of creatinine is in clinical diagnostics as a key parameter for evaluating renal function. It serves as the basis for calculating estimated glomerular filtration rate (eGFR), which is essential for diagnosing and monitoring kidney diseases. In laboratory medicine, creatinine measurements are used to correct urine analyte concentrations for dilution variations. Beyond clinical applications, it serves as an important standard and calibrator in in vitro diagnostic reagents and quality control materials. Additional uses include its role in research settings for studying muscle metabolism and as a component in certain cell culture media. The compound's stability and predictable behavior make it invaluable for standardizing various biochemical assays.

Application Market

The market for creatinine is substantial and primarily driven by the global in vitro diagnostics industry. As an essential test in routine clinical practice, demand for creatinine measurement reagents and calibrators remains consistently high across healthcare systems worldwide. The market includes both synthetic creatinine for diagnostic manufacturing and reference materials for laboratory standardization. Major diagnostic companies and chemical suppliers serve this global market, with distribution channels extending to hospital laboratories, reference labs, and research institutions. Market growth is sustained by the increasing prevalence of chronic kidney disease, expanding geriatric populations, and the routine inclusion of creatinine testing in health screenings and monitoring protocols across clinical settings.

Important Considerations

Appropriate use of creatinine in diagnostic applications requires attention to analytical specificity and potential interfering substances. Different measurement methods (Jaffe reaction vs. enzymatic assays) may show varying susceptibility to interference from compounds like glucose, ketones, or certain medications. Proper calibration and quality control procedures are essential for maintaining measurement accuracy in clinical laboratories. Storage conditions should maintain stability, with protection from moisture and extreme temperatures. While creatinine itself has low toxicity, handling should follow good laboratory practices to ensure purity and prevent contamination. Interpretation of creatinine values in clinical practice must consider individual factors including age, sex, muscle mass, and dietary influences that can affect baseline levels independent of renal function.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

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For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

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Suitable for more than 50kg 
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For sample orders: 
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For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

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Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

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