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tesofensine cas 195875-84-4 white solid R&D support customized

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CAS No.:

195875-84-4

Grade:

Pharmaceutical Grade

Content:

99%

Port:

jinan

Brand:

Packaging:

bag

Sample Available:

Yes

Price valid (until):

2025-11-27

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Jinan topfull chemical co.,ltd

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

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Product Details
Seller Information
Inquiry History

Description

Tesorofenzin is a tricyclic monoamine reuptake inhibitor. It can effectively inhibit the reuptake of neurotransmitters dopamine (DA; IC50 = 6.5 nM), norepinephrine (NE; IC50 = 1.7 nM), and serotonin (5-HT; IC50 = 11 nM) in the synaptic cleft, and has the potential to be used as an anti-obesity agent.

ECHEMI Editorial Reference

Tesofensine ((1R, 2R, 3S, 5S)-3-(3, 4-dichlorophenyl)-2-(ethoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane)) is an inhibitor of neuronal reuptake of dopamine, noradrenaline, and serotonin. Tesofensine was developed for the treatment of Alzheimer's and Parkinson's disease but lacked efficacy. Meta-analysis revealed that tesofensine (0.125–1.0 mg, once daily; oral) produced dose-dependent weight loss, and 32% of obese patients had ≥ 5% weight loss following 14 wk of treatment. Weight loss was accompanied by hypophagia, suggesting an appetite suppressant action[2].
Tesofensine is a dopamine, serotonin, and noradrenaline (triple) reuptake inhibitor originally developed by NeuroSearch for the treatment of Alzheimer's disease and Parkinson's disease. Development of the compound for these neurological indications was unsuccessful but significant weight loss was reported during the clinical trials in Parkinson's disease. Hence, tesofensine is now being developed by NeuroSearch for the treatment of obesity and type 2 diabetes[1].

Basic Info

Product Name:
tesofensine

Other Name:
(1S,3S,4R,5R)-3-(3,4-dichlorophenyl)-4-(ethoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane;(1R,2R,3S,5S)-3-(3,4-Dichlorophenyl)-2-(ethoxymethyl)-8-methyl-8-azabicyclo[3.2.1]octane;Tesofensine-13C-d3;8-Azabicyclo[3.2.1]octane, 3-(3,4-dichlorophenyl)-2-(ethoxymethyl)-8-methyl-, (1R,2R,3S,5S)-;Tesofensine 500mcg Tablets;Tesofensine 0.5mg Tablets

CAS No.:
195875-84-4

Molecular Formula:
C17H23Cl2NO

InChIKeys:
VCVWXKKWDOJNIT-ZOMKSWQUSA-N

Molecular Weight:
328.28

Exact Mass:
328.28

UNII:
BLH9UKX9V1

Color/Form:
White to off-white

Categories:
Nervous System Drugs

Characteristics

Density:
1.161±0.06 g/cm3(Predicted)

Boiling Point:
396.6±42.0 °C(Predicted)

PKA:
10.46±0.60(Predicted)

Critical Temperature & Pressure:
Store at -20°C

See More tesofensine Properties 
Seller Information

Business Type:
Trader

Main Products:
Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

Location:
RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2022

Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!

Inquiry History

86 Inquiries

Country	Product	Purchase Quantity	Date Posted
United Kingdom	CAS: 195875-84-4	10 G	Oct 25, 2025
Indonesia	High quality Tesofensine 500mcg cas 195875-84-4 100pcs/bottle	4	Apr 18, 2025
United States	High Purity Tesofensine Powder 99% White Powder CAS 195875-84-4 EGC-Tesofensine Powder	1 KG	Oct 27, 2023
United Kingdom	tesofensine	100 PCS	Oct 25, 2026
United States	tesofensine tablet	10 MT	Sep 27, 2026
United Kingdom	tesofensine	1 G	Sep 23, 2026
Philippines	Tesofenside tablet	10 MT	Jul 29, 2026
United States	Tesofensine API	500 MG	Jul 18, 2026
Belgium	Tesofensine	1000 PCS	Jun 1, 2026
Belgium	Tesofensine	100 G	May 31, 2026
Canada	tesofensine	50 MG	Apr 27, 2026
United States	Tesofensine	100 G	Apr 23, 2026
United Kingdom	Tesofensine	1 G	Apr 20, 2026
United States	Tesofensine	5 MT	Apr 19, 2026
United States	Tesofensine	1 MT	Apr 18, 2026
United Kingdom	Tesofensine	1 MT	Apr 3, 2026
United States	Tesofensine	100 G	Feb 27, 2026
United States	Tesofensine	60 G	Feb 15, 2026
United States	Tesofensine	100 G	Feb 13, 2026
United Kingdom	Tesofensine	10 G	Feb 7, 2026

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