Product Name: (3,5-Difluoro-2-hydroxyphenyl)boronic Acid
CAS No.: 1150114-51-4
Molecular Formula: C₆H₅BF₂O₃
Purity: ≥97% (HPLC)
Appearance: White to off-white crystalline powder

Product Description
(3,5-Difluoro-2-hydroxyphenyl)boronic Acid (CAS 1150114-51-4) is a high-purity boron-containing intermediate designed for advanced pharmaceutical and chemical synthesis. Its unique structure, featuring both boronic acid and hydroxyl groups on a difluorinated aromatic ring, makes it an ideal building block for Suzuki-Miyaura cross-coupling reactions, widely used in constructing complex bioactive molecules.

This compound is particularly valuable in the development of targeted therapies, including potential applications in oncology and central nervous system (CNS) drugs, where fluorine and boron motifs are critical for enhancing metabolic stability and binding affinity.

Key Features

• High Reactivity: Boronic acid group enables efficient C–C bond formation in coupling reactions.

• Dual Functionalization: Combines fluorine atoms (for lipophilicity and stability) with a hydroxyl group (for hydrogen bonding or further derivatization).

• Pharmaceutical Relevance: Suitable for synthesizing kinase inhibitors, protease inhibitors, and other small-molecule APIs.

• Quality Assurance: Rigorously tested with HPLC and NMR documentation.

Applications

• Pharmaceutical Intermediates: Key precursor for anticancer, antiviral, and CNS-targeting agents.

• Agrochemicals & Materials: Building block for fluorinated compounds in crop protection and functional materials.

• Custom Synthesis: Available for tailored R&D and industrial-scale production.

Packaging & Storage

• Packaging: 1g, 5g, 10g, 100g; custom packaging available.

• Storage: Store in a sealed container under inert atmosphere at 2–8°C. Protect from moisture and light.

Why Choose Our Products?

• Technical support and custom synthesis services.

• Reliable supply with complete regulatory documentation.

• Collaborative partnerships with GMP-certified manufacturers and R&D centers.

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