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99% Raw Material Mavacamten Pharmaceutical Powder CAS 1642288-47-8

10 Inquiries

Unit Price:

$100/G FOB

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CAS No.:

1642288-47-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

qingdao

Brand:

Packaging:

according to your request

Price valid (until):

2028-11-23

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NATURE INDUSTRIAL LIMITED

Company Type:

Trader

Location:

Hongkong, China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

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Product Details
Seller Information
Inquiry History

Description

Product Description

Product name	High Quality Mavacamten Powder
Chemical name	Mavacamten
C as	1642288-47-8
Purity	99.0%min
Appearance	White or almost white micro crystalline powder
MF	C15H19N3O2
Molecular Weight	273.33
Residue on ignation	Not more than 0.2%

Application:
Mavacamten(MYK-461)is a first-in-class allosteric inhibitor of cardiac myosin that promises to provide clinicians with targeted therapy for these patients. It is a mechanistically novel small molecule that acts on the sarcolemma to specifically inhibit contractility and has been proposed as a treatment for HCM.

The mechanism of action of Mavacamten is to reversibly bind to cardiac myosin, inhibit its excessive interaction with actin, and thereby reduce the excessive contractility and energy consumption of cardiac cells. In patients with hypertrophic cardiomyopathy (HCM), this drug can effectively alleviate left ventricular outflow tract obstruction (LVOTO), improve diastolic function, and alleviate symptoms such as angina and dyspnea. Its precise targeted regulatory effect reduces the side effects of traditional treatments such as beta blockers or surgery, providing more optimized treatment options for HCM patients. Clinical studies have shown that Mavacamten can significantly improve patients' exercise tolerance and quality of life.

Packing:

Mavacamten Powder CAS 1642288-47-8 usual package is foil bag for 1kg

Or 25KG/drum,or according to your requirement.

FAQ

Q1: Are you the manufacturer or trade company?
--We are the manufacturer in China, founded on 2011.

Q2: When will the product be shipped after payment?
--The parcel will be get ready and shipped within 1 day.

Q3: How long will it take to receive the parcel?
--3-5days for the US market; 3-7days for the others.

Q4: What can I do if I don't have the ability to clear the custom.
--We got experience after doing export for many years, so don't worry we can handle that.

Q5: Why should you buy from us not from other suppliers?
---Jinan Jianfeng Chemical Co.,Ltd is a medium-sized enterprise integrating the development, production, sales and export and import trade of chemical products. Our factory has perfect infrastructure, advanced processing technology and completed detection means.

ECHEMI Editorial Reference

Mavacamten is under investigation in clinical trial NCT03442764 (A Phase 2 Study of Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)).
Mavacamten（MYK-461）is a first-in-class allosteric inhibitor of cardiac myosin that promises to provide clinicians with targeted therapy for these patients. It is a mechanistically novel small molecule that acts on the sarcolemma to specifically inhibit contractility and has been proposed as a treatment for HCM.

Basic Info

Product Name:

Mavacamten

Other Name:

MYK-461 (SAR-439152);SAR 439152;SAR439152;SAR-439152;SAR-439152; SAR 439152; SAR439152; MYK-461; MYK 461; MYK461; MAVACAMTEN;MYK-461 - Mavacamten | SAR439152;Mavacamten (MYK-461;6-([(1S)-1-phenylethyl]amino)-3-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione

CAS No.:

1642288-47-8

Molecular Formula:

C15H19N3O2

InChIKeys:

RLCLASQCAPXVLM-NSHDSACASA-N

Molecular Weight:

273.33

Exact Mass:

273.147726857

EC Number:

213-161-7

UNII:

QX45B99R3J

Color/Form:

White to off-white

Categories:

Other Chemical Drugs

Characteristics

Density:

1.19±0.1 g/cm3(Predicted)

PKA:

8.83±0.40(Predicted)

Critical Temperature & Pressure:

Storage temp. -20°C

Seller Information

Business Type:
Trader

Main Products:
Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

Location:
Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$50 million-$100 million

Total Employees:
51-100

Year of Establishment:
2012

We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

"Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.

Inquiry History

10 Inquiries

Country	Product	Purchase Quantity	Date Posted
Australia	Mavacamten	1 MT	May 15, 2025
Russia	Mavacamten	100 G	Mar 31, 2025
India	Mavacamten	1.00 KG	Mar 7, 2024
India	URSODEOXYCHOLIC ACID	10.00 KG	Mar 6, 2024
India	Upadacitinib	10.00 KG	Mar 6, 2024
India	Acarbose	10.00 KG	Mar 6, 2024
India	Ripretinib	10.00 KG	Mar 6, 2024
India	MAVACAMTEN API POWDER	25.00 KG	Feb 29, 2024
India	MAVACAMTEN	25 KG	Feb 28, 2024
India	Mavacamten	10.00 MT	Jan 22, 2024

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99% Raw Material Mavacamten Pharmaceutical Powder CAS 1642288-47-8

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