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Cyclohexanone CAS:108-94-1

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CAS No.:

108-94-1

Grade:

Industrail Grade

Content:

99%

Port:

SHNAGHAI

Brand:

Orient

Packaging:

25L, 200L, 1000L, customized

Price valid (until):

2025-12-26

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Description	Cyclohexanone, a colorless liquid is a cyclic ketone. It is an important building block for the synthesis of a variety of organic compounds. Majority of the cyclohexanone synthesized is utilized as an intermediate in the synthesis of nylon. Used as a polyvinyl chloride (PVC) solvent, cyclohexanone caused contact dermatitis in a woman manufacturing PVC fluidotherapy bags. Cyclohexanone probably does not cross react with cyclohexanone resin. A cyclohexanone-derived resin used in paints and varnishes caused contact dermatitis in painters.
Chemical Properties	Cyclohexanone is a water-white to slightly yellow liquid with a peppermint-like or acetone-like odor. The Odor Threshold is 0.12 0.24 ppm in air.
Physical properties	Clear, colorless to pale yellow, oily liquid with a peppermint-like odor. Experimentally determined detection and recognition odor threshold concentrations were identical: 480 μg/m³ (120 ppm_v) (Hellman and Small, 1974).
Occurrence	Reported present in Cistus labdaniferus.
Uses	Industrial solvent for cellulose acetate resins, vinyl resins, rubber, and waxes; solventsealer for polyvinyl chloride; in printing industry; coating solvent in audio and videotape production
Uses	Cyclohexanone is used as an industrial solvent and paint remover. It acts as a precursor to nylon 6,6 and nylon 6 and cyclohexanone oxime, which gives caprolactam on rearrangement. Further, it is used as a chemical reaction medium, adhesives, sealants and agricultural products.
Uses	Cyclohexanone is used in the productionof adipic acid for making nylon; in thepreparation of cyclohexanone resins; and asa solvent for nitrocellulose, cellulose acetate,resins, fats, waxes, shellac, rubber, and DDT..
Definition	ChEBI: A cyclic ketone that consists of cyclohexane bearing a single oxo substituent.
Synthesis Reference(s)	Canadian Journal of Chemistry, 62, p. 1031, 1984 DOI: 10.1139/v84-171 Tetrahedron Letters, 25, p. 3309, 1984 DOI: 10.1016/S0040-4039(01)81371-X
General Description	A colorless to pale yellow liquid with a pleasant odor. Less dense than water . Flash point 111°F. Vapors heavier than air. Used to make nylon, as a chemical reaction medium, and as a solvent.
Air & Water Reactions	Flammable. Soluble in water.
Reactivity Profile	Cyclohexanone forms an explosive peroxide with H2O2, and reacts vigorously with oxidizing materials (nitric acid).
Health Hazard	Inhalation of vapors from hot material can cause narcosis. The liquid may cause dermatitis.
Health Hazard	The toxicity of cyclohexanone in test specieswas found to be low to moderate. Exposureto its vapors can produce irritation in the eyesand throat. Splashing into the eyes can damagethe cornea. Throat irritation in humansmay occur from 3–5 minute exposure to a50-ppm concentration in air. The symptomsof chronic toxicity in animals from its inhalationwere liver and kidney damage, as wellas weight loss. However, its acute toxicitywas low below 3000 ppm. The symptomsin guinea pigs were lacrimation, salivation,lowering of heart rate, and narcosis. Exposureto 4000 ppm for 4–6 hours was lethalto rats and guinea pigs. The oral toxicity of this compound waslow. Ingestion may cause narcosis and depressionof the central nervous system. It canbe absorbed through the skin. LD50 value, dermal (rabbits): 1000 mg/kg LD50 value, intraperitoneal (rats): 1130 mg/kg.
Fire Hazard	HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Flammability and Explosibility	Flammable
Chemical Reactivity	Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.
Contact allergens	Used as a polyvinyl chloride solvent, cyclohexanone caused contact dermatitis in a woman manufacturing PVC fluidotherapy bags. Cyclohexanone probably does not cross-react with cyclohexanone resin. A cyclohexanone-derived resin used in paints and varnishes caused contact dermatitis in painters
Safety Profile	Suspected carcinogen. Moderately toxic by ingestion, inhalation, subcutaneous, intravenous, and intraperitoneal routes. A skin and severe eye irritant. Human systemic effects by inhalation: changes in the sense of smell, conjunctiva irritation, and unspecified respiratory system changes. Human irritant by inhalation. Mdd narcotic properties have also been ascribed to it. Human mutation data reported. Experimental reproductive effects. Flammable liquid when exposed to heat or flame; can react vigorously with oxidizing materials. Slight explosion hazard in its vapor form, when exposed to flame.Reaction with hydrogen peroxide + nitric acid forms an explosive peroxide. To fight fire, use alcohol foam, dry chemical, or COa. When heated to decomposition it emits acrid smoke and irritating fumes. See also KETONES and CYCLOHEXANE.
Synthesis	It may be synthesized on a laboratory scale by the oxidation of cyclohexanol.
Potential Exposure	May form explosive mixture with air. Contact with oxidizing agents or nitric acid may cause a violent reaction. Do not use brass, copper, bronze, or lead fittings. Attacks many coatings and plastic materials.
First aid	If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.

Cyclohexanone Usage And Synthesis

Chemical properties	Cyclohexanone is a colorless, clear liquid with soil smell; its impure product appears as light yellow color. It is miscible with several other solvents. easily soluble in ethanol and ether. The lower exposure limit is 1.1% and the upper exposure limit is 9.4%. Cyclohexanone may be incompatible with oxidizers and nitric acid. Cyclohexanone is a primarily used in industry, up to 96%, as a chemical intermediate in the production of nylons 6 and 66. Oxidation or conversion of cyclohexanone yields adipic acid and caprolactam, two of the immediate precursors to the respective nylons. Cyclohexanone can also be used as a solvent in a variety of products, including paints, lacquers, and resins. It has not been found to occur in natural processes.
Application	Cyclohexanone is mostly captively consumed, either isolated or as a mixture, in the production of nylon intermediates (adipic acid and Caprolactam). Around 4% is consumed in markets other than nylon, such as solvents for paints, dyes and pesticides. Cyclohexanone is also used in the manufacture of pharmaceuticals, films, soaps and coatings. Fibrant is one of the largest producers of Cyclohexanone, a raw material used in the production of Caprolactam.
Uses	Cyclohexanone is an important chemical raw material, being the major intermediates of making nylon, caprolactam and adipic acid. It is also an important industrial solvent, for example, for paints, especially for those containing nitrocellulose, vinyl chloride polymers and their copolymers or methacrylate polymer paints. Used as an excellent solvent for pesticides such as organophosphate insecticide. It is used as a solvent for dyes, viscous solvents for piston aviation lubricants, solvents for greases, waxes and rubbers. Also used as leveling agent for dyeing and fading silk; degreasing agents for polishing metal; wood coloring paint; also used for cyclohexanone stripping, decontamination and spot removal. Cyclohexanone and cyanoacetic acid can have condensation reaction to generate cyclohexylidene acetic acid, and then followed by elimination and decarboxylation to get cyclohexene acetonitrile, and finally giving cyclohexene ethylamine by hydrogenation [3399-73-3]. Cyclohexene ethylamine is a intermediate for some drugs.
Production method	In the 1940s, the industrial production of cyclohexanone mainly applied hydrogenation of phenol to generate cyclohexanol, followed by dehydrogenation to give cyclohexanone. In the 1960s, with the development of petrochemical industry, the cyclohexane oxidation production method gradually dominated. In 1967, the one step method of phenol hydrogenation, developed by the Netherlands National Mining Company (DSM) was industrialized. This method has short production process, good product quality and high yield, but the raw materials of phenol and catalyst are expensive, so the majority of the industry still adopts the cyclohexane oxidation method. 1. Phenol method takes nickel as a catalyst; first apply hydrogenation of phenol to give cyclohexanol, followed by dehydrogenation to give cyclohexanone using zinc as the catalyst for zinc. 2. Cyclohexane oxidation method uses cyclohexane as the raw material; first apply non-catalyst condition; use oxygen-rich air for oxidation to give cyclohexyl hydroperoxide, followed by decomposition into the mixture of cyclohexanol, cyclohexanone, alcohol and ketone in the presence of tert-butyl chromate catalyst; further apply a series of distillation refinement to get qualified products. Raw material consumption quota: cyclohexane (99.6%) 1040kg / t. 3. Benzene hydrogenation oxidation method; benzene subjects to hydrogenation (with hydrogen) at 120-180 ℃ in the presence of nickel catalyst to generate cyclohexane; cyclohexane has oxidation reaction with air at 150-160 ℃, 0.908MPa to obtain the mixture of cyclohexanol and cyclohexanone; separate them to obtain the cyclohexanone product. Cyclohexanol is dehydrogenated at 350-400 ° C in the presence of a zinc-calcium catalyst to produce cyclohexanone. Raw material consumption quotas: benzene (99.5%) 1144kg / t, hydrogen (97.0%) 1108kg / t, caustic soda (42.0%) 230kg / t.

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Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

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Q3: How can I buy? What is the payment method?

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Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

Cyclohexanone

Other Name:

Cyclohexanone;Anone;Hexanon;Hytrol O;Nadone;Pimelic ketone;Pimelin ketone;Sextone;Anon;NSC 5711;C 0489

CAS No.:

108-94-1

UN No.:

1915

Molecular Formula:

C6H10O

InChIKeys:

InChIKey=JHIVVAPYMSGYDF-UHFFFAOYSA-N

Molecular Weight:

98.14

Exact Mass:

98.14

EC Number:

203-631-1

UNII:

5QOR3YM052

ICSC Number:

0425

NSC Number:

5711

UN Number:

1915

DSSTox ID:

DTXSID6020359

Color/Form:

OILY LIQUID|WATER-WHITE TO PALE YELLOW LIQUID|Water-white to pale-yellow liquid ...

HScode:

2914220000

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

17.07000

XLogP3:

0.76

Appearance:

Cyclohexanone appears as a colorless to pale yellow liquid with a pleasant odor. Less dense than water . Flash point 111°F. Vapors heavier than air. Used to make nylon, as a chemical reaction medium, and as a solvent.

Density:

0.9478 g/cm³ @ Temp: 20 °C

Melting Point:

-31 °C

Boiling Point:

1.4 °C @ Press: 1.0 Torr

Flash Point:

116 °F

Refractive Index:

n 20/D 1.450(lit.)

Water Solubility:

150 g/L (10 ºC)Flammable. soluble in water.

Storage Conditions:

Keep containers closed; prohibit open flame. Store in cool and dark plane.

Vapor Pressure:

3.4 mm Hg ( 20 °C)

Vapor Density:

3.4 (vs air)

Toxicity:

LD50 orally in rats: 1.62 ml/kg (Smyth)

Flammability characteristics:

Class II Combustible Liquid: Fl.P. at or above 100°F and below 140°F.

Explosive limit:

vol% in air: 1.1.4 (at 100°C)

Odor:

ODOR REMINISCENT OF PEPPERMINT & ACETONE

PKA:

11.3None

OH:

6.39e-12 cm3/molecule*sec

Henrys Law Constant:

9.00e-06 atm-m3/mole

Dissociation Constants:

11.3

Air and Water Reactions:

Flammable. Soluble in water.

Reactive Group:

Ketones

Reactivity Alerts:

Highly Flammable

Reactivity Profile:

CYCLOHEXANONE forms an explosive peroxide with H2O2, and reacts vigorously with oxidizing materials (nitric acid). (NTP, 1992)

Peroxide Forming Chemical:

Cyclohexanone|D*: Other compounds that may form peroxides|9 samples, >1yrs, 1-3 ppm|Management of time-sensitive chemicals (JCHAS)

Autoignition Temperature:

788 °F (USCG, 1999)|420 °C; 788 °F|420 °C

Heat of Combustion:

-15,430 btu/lb= -8570 cal/g= -358.8x10+5 J/kg

Ionization Potential:

9.14 eV

Flammable Limits:

Lower flammable limit: 1.1% by volume at 212 °F; Upper flammable limit: 9.4% by volume|Class II Combustible Liquid: Fl.P. at or above 100°F and below 140°F.

Physical Dangers:

The vapour is heavier than air. As a result of flow, agitation, etc., electrostatic charges can be generated.

Corrosivity:

Corrosive

Heat of Vaporization:

45.06 kJ/mol @ 25 °C

Critical Temperature & Pressure:

Critical temp: 673 °F= 356 °C= 629 deg K; Critical pressure: 560 psia= 38 atm= 3.8 MN/sq m

See More Cyclohexanone Properties 

Hazard Identification

Classification of the substance or mixture

Flammable liquids, Category 3

Acute toxicity - Category 4, Inhalation

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H226 Flammable liquid and vapour H332 Harmful if inhaled
Prevention	P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground and bond container and receiving equipment. P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment. P242 Use non-sparking tools. P243 Take action to prevent static discharges. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower]. P370+P378 In case of fire: Use ... to extinguish. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P317 Get medical help.
Storage	P403+P235 Store in a well-ventilated place. Keep cool.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

NO open flames, NO sparks and NO smoking. Above 44Â°C use a closed system, ventilation and explosion-proof electrical equipment. Prevent build-up of electrostatic charges (e.g., by grounding). Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Fireproof. Separated from strong oxidants.Keep containers closed; prohibit open flame. Store in cool and dark plane.

See More Cyclohexanone Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

59 Inquiries

Country	Product	Purchase Quantity	Date Posted
Thailand	Cyclohexanone	1.00 MT	Nov 6, 2024
Germany	cyclohexanone	300 TON	Jun 17, 2024
Thailand	Cyclohexanone	1.00 MT	Sep 25, 2024
India	Cyclohexanone	50.00 MT	Feb 18, 2024
Netherlands	Cyclohexanone	100.00 KG	Jun 12, 2025
United Arab Emirates	Cyclohexanone	1.00 20' Fcl	Feb 8, 2025
Pakistan	Cyclohexanone	25 MT	Sep 23, 2024
Serbia	Cyklohekasnone	20 MT	Jun 21, 2026
Singapore	Cyclohexanone	1.00 KG	Apr 7, 2026
Pakistan	cyclohexanone	1 20' Fcl	Jun 27, 2025
Brazil	cyclohexanone	20 MT	May 27, 2025
India	Cyclohexanone	1.00 MT	Apr 10, 2025
Egypt	Cyclo Hexanone	1.00 20' Fcl	Mar 14, 2025
Vietnam	Cyclohexanone	2.00 20' Fcl	Dec 17, 2024
Vietnam	Cyclohexanone	2.00 20' Fcl	Dec 17, 2024
India	Cyclohexanone	5.00 MT	Dec 12, 2024
United States	Cyclohexanone	500 G	Sep 11, 2024
India	Cyclohexanone	50 MT	Jun 24, 2024
India	CYCLOHEXANONE	1.00 20' Fcl	Oct 26, 2023
Pakistan	Cyclohexanone	100 KG	Aug 23, 2023

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Cyclohexanone CAS:108-94-1

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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