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TRIS HCL 1185-53-1

Name: TRIS HCL 1185-53-1
Brand: Orient
SKU: pr2511301014
Price: 3 USD
Availability: InStock

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CAS No.:

1185-53-1

Grade:

Industrial Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

25kg/bag,500kg/bag, customized

Price valid (until):

2025-12-30

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information

Description

TRIS hydrochloride Basic information

Product Name:	TRIS hydrochloride
Synonyms:	3-propanediol,2-amino-2-(hydroxymethyl)-hydrochloride;trizmahydrochloride(trishydrochloride);Tris(2-amino-2-hydroxymethyl)-1,3-propanediol, hydrochloride;Tris(hydroxymethyl)aminomethane hydrochloride, extra pure, 99+%;TrisHCl,mole-readyform,molecularbiologygrade;TRISHYDROXYMETHYLAMINOMETHANE HYDROCHLORIDE BIO-REFINED;TRIS(HYDROXYMETHYL)AMINOMETHANEHYDROCHLORIDE,BIOTECHGRADE;TRIS(HYDROXYMETHYL)AMINOMETHANEHYDROCHLORIDE,CRYSTAL,REAGENT
CAS:	1185-53-1
MF:	C4H12ClNO3
MW:	157.6
EINECS:	214-684-5
Product Categories:	Buffer;1185-53-1
Mol File:	1185-53-1.mol

TRIS hydrochloride Chemical Properties

Melting point	150-152 °C
Boiling point	225℃[at 101 325 Pa]
density	1.05 g/mL at 20 °C
vapor pressure	0Pa at 20℃
storage temp.	room temp
solubility	H₂O: 4 M at 20 °C, clear, colorless
form	crystalline
color	clear colorless (40 % (w/w) in H₂O) solution
PH	2.5-4.0 (25℃, 4M in H2O)
PH Range	7.0 - 9.0
pka	8.1(at 25℃)
biological source	synthetic
Water Solubility	SOLUBLE
λmax	λ: 260 nm Amax: 0.12 λ: 280 nm Amax: 0.08
Sensitive	Hygroscopic
BRN	3675235
Stability:	Stable. Incompatible with strong oxidizing agents, bases, moisture.
InChIKey	QKNYBSVHEMOAJP-UHFFFAOYSA-N
LogP	-3.6 at 20℃
CAS DataBase Reference	1185-53-1(CAS DataBase Reference)
EPA Substance Registry System	1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride (1185-53-1)
Absorption	≤0.05 at 290nm at 40%

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
WGK Germany	3
RTECS	TY2900000
F	3
TSCA	Yes
HS Code	29221980

TRIS hydrochloride Usage And Synthesis

Description	Abbreviated as Tris HCl (TRIS hydrochloride), Tris (hydroxymethyl) aminomethane hydrochloride is an organic compound commonly utilized in buffer solutions such as TAE or TBE for electrophoresis gels. It boasts high solubility in water and offers utility within the pH range of 7.0-9.0.
Chemical Properties	TRIS hydrochloride is a white crystalline powder that has a pKa of 8.08 at 25°C and pH range of 7.0 to 9.0 that coincides with the physiological pH of most living organisms because of which it is commonly used as a component of buffer solutions in biology, biochemistry and molecular biology applications. Tris salts are also used for crystallization of proteins at various pH values. Neither Tris base nor Tris hydrochloride by itself provide adequate buffering capacity. Generally the two need to be mixed together to provide a buffer with pH between 7 and 9 to provide adequate buffering.
Uses	Tris Hydrochloride is a buffering medium for electrophoresis, molecular biology, and cell culture applications. It may be combined with Tris Base to simplify Tris buffer preparation. Tris Hydrochloride has been incorporated in coelomic fluid and in Cortland medium to store unfertilized rainbow trout eggs. In immunohistochemistry, Tris Hydrochloride has also been used with urea as a method for antigen retrieval.

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

Tris(hydroxymethyl)aminomethane hydrochloride

Other Name:

1,3-Propanediol,2-amino-2-(hydroxymethyl)-,hydrochloride (1:1);1,3-Propanediol,2-amino-2-(hydroxymethyl)-,hydrochloride;Tris chloride;Tris hydrochloride;Tris(hydroxymethyl)aminomethane hydrochloride;Tromethamine hydrochloride;Trizma hydrochloride;2-Amino-2-(hydroxymethyl)-1,3-propanediol hydrochloride;Tri(hydroxymethyl)aminomethane hydrochloride;T 6666;Tris-hydrochloric acid;Tris-HCl;35087-75-3;150551-82-9

CAS No.:

1185-53-1

Molecular Formula:

C4H11NO3.ClH

InChIKeys:

InChIKey=QKNYBSVHEMOAJP-UHFFFAOYSA-N

Molecular Weight:

157.59600

Exact Mass:

157.05100

EC Number:

214-684-5

UNII:

383V75M34E

DSSTox ID:

DTXSID4044373

HScode:

2922199090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

86.71000

XLogP3:

-0.83690

Appearance:

white crystalline powder

Density:

1.05 g/mL at 20ºC

Melting Point:

150.0-150.8 °C

Boiling Point:

357ºC at 760 mmHg

Flash Point:

169.7ºC

Water Solubility:

H2O: soluble

Storage Conditions:

Store at RT.

See More Tris(hydroxymethyl)aminomethane hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Tris(hydroxymethyl)aminomethane hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

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We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221
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