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Home > Biochemical Engineering > Polypeptide > Retatrutide for Sale > Retatrutide Lyophilized API Powder Bulk Wholesale Raw Material
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Retatrutide Lyophilized API Powder Bulk Wholesale Raw Material buy - image1

Retatrutide Lyophilized API Powder Bulk Wholesale Raw Material

6915 Inquiries

Unit Price:

$120-150/G FOB

Get Latest Price
CAS No.:

2381089-83-2

Grade:

Pharmacy Grade

Content:

95%

Port:

Shanghai/Shenzhen

Brand:

NA

Packaging:

as require

Price valid (until):

2026-12-31

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

semaglutide,tirzepatide,liraglutide,retaturtide

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Retatrutide

    CAS NO.2381089-83-2

    Appearance: White Powder

    Purity:>99%

    Bacterial endotoxins:<10EU/mg

    ECHEMI Editorial Reference
    Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.

    Basic Info
    Product Name:

    Retatrutide

    Other Name:

    Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

    CAS No.:

    2381089-83-2

    Molecular Formula:

    C221H342N46O68

    InChIKeys:

    MLOLQJNKXBNWFW-SAGGEDDASA-N

    Molecular Weight:

    4731.33

    EC Number:

    200-001-8

    Color/Form:

    White lyophilized

    Categories:

    Polypeptide

    Characteristics
    Water Solubility:

    Soluble in water (5mg/ml).

    Storage Conditions:

    -20°C

    Critical Temperature & Pressure:

    -20°C

    Research
    Class:

    Triple agonist — GCGR, GIPR, GLP-1R

    Status:

    Investigational (Phase 3)

    Mechanism:

    Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

    EC50 (Human GCGR):

    5.79 nM

    EC50 (Mouse GIPR):

    0.191 nM

    EC50 (Mouse GLP1R):

    0.794 nM

    EC50 (Mouse GCGR):

    2.32 nM

    EC50 (Human GLP1R):

    0.775 nM

    EC50 (Human GIPR):

    0.0643 nM

    Source:

    Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

    Clinical Development:

    NCT04881760; NCT05882045; NCT06354660

    References
    ChEMBL:

    CHEMBL5095485

    DrugBank:

    DB18993

    KEGG DRUG:

    D12430

    PubChem:

    PubChem

    Disclaimer:

    Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    semaglutide,tirzepatide,liraglutide,retaturtide

    Location:

    No.109 Yongfu Road, Chongchuan District, Nantong, Jiangsu Province,226000 China

    Payment Terms:

    TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    15

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    101-200

    Year of Establishment:

    2020

    Certifications:

    ISO 9001,semaglutide US DMF

    Company Profile

    Xiushi Biopharma is an international leading high-tech enterprise focusing on large-scale biosynthesis of polypeptide drugs. We provide all-round products and services from drug research, clinical development to access to market for global biotechnology and pharmaceutical enterprises.

    We have professional and experienced engineers and scientists, providing new polypeptide drug biosynthesis solutions, which help partners stay ahead of the polypeptide drug discovery, clinical development and market production.

    We have more than 5000 square meters of R&D center and 20000 square meters of intelligent manufacturing base, which can meet the needs of different customers and products, while meeting the GMP conditions for drug production.

    XIUSHI Biopharma is a CDMO specializing in the manufacturing of synthetic peptides and oligonucleotides for early-phase, late-phase development, and commercial production. XIUSHI Biopharma excels in large-scale, late-phase, and commercial production, boasting the production capability in kgs quantities.

    We specialize in contract development and manufacturing organization ("CDMO") services, which include peptide chemistry, manufacturing, and controls ("CMC") development; as well as contract manufacturing organization ("CMO") services, encompassing peptide new chemical entities (NCEs) and generic drug commercial manufacturing.

    XIUSHI Biopharma provides a comprehensive peptide-centric CDMO platform with vertically integrated capabilities in peptide drug development and manufacturing, adhering strictly to Good Manufacturing Practice (GMP) standards mandated by major regulatory authorities globally.

    GMP Compliance
    XIUSHI Biopharma's GMP program strictly adheres to FDA/EU GMP guidelines.

  • Inquiry History
    6915 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Retatrutide 2381089-83-2

    3 MT Mar 28, 2026
    United Kingdom

    Retatrutide - 2381089-83-2

    1 G Feb 10, 2026
    United States

    Retatrutide CAS 2381089-83-2 10mg vial

    20 MT Mar 7, 2026
    United States

    Factory Retatrutide API 99% Purity CAS 2381089-83-2

    5 KG Nov 10, 2025
    United Kingdom

    Peptide powder Retatrutide 99% pure for Body building cas 2381089-83-2 Weight Loss Peptide with COA

    1 MT Mar 22, 2026
    United States

    2381089-83-2

    100 G Jul 14, 2026
    United States

    2381089-83-2

    100 G Feb 24, 2026
    United States

    2381089-83-2

    100 MT Dec 9, 2023
    United States

    Retatrutide 2381089-83-2

    200 MG May 16, 2026
    United Kingdom

    2381089-83-2 retatrutide

    300 MG Feb 13, 2026
    United States

    Retatrutide 2381089-83-2 wholesale

    500 MT Nov 3, 2023
    Poland

    CAS 2381089-83-2 (Custom Peptide)

    40 MT Apr 10, 2026
    Austria

    Peptide Retatruide CAS 2381089-83-2

    100 MT Apr 4, 2026
    United States

    Retatrutide CAS 2381089-83-2 99%

    10 PCS Feb 21, 2026
    Austria

    Retatrutide CAS 2381089-83-2 10mg vial

    20 PCS Feb 10, 2026
    United States

    GLP-1 / GIP Retatrutide cas 2381089-83-2

    1 MT Oct 16, 2024
    United States

    Retatrutide 99% High Quality CAS 2381089-83-2

    1 G Jan 23, 2026
    United States

    Injection Peptide Tirzepatide/Retatrutide/ Semaglutide Peptides CAS 2381089-83-2

    10  Oct 21, 2023
    Australia

    GMP Grade 99% Retatrutide Lyophilized Powder CAS 2381089-83-2

    10 G Jun 12, 2026
    Palestine

    Factory 99% Purity Retatrutide Peptide CAS 2381089-83-2 Door-To-Door Service

    10 MG Mar 16, 2026
    Post an enquiry for this product
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