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99% Promethazine HCl Powder CAS 58-33-3 Factory with Safe Shipping

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CAS No.:

58-33-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Brand:

Packaging:

25kg/Cardboard Drum

Price valid (until):

2026-01-09

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NATURE INDUSTRIAL LIMITED

Company Type:

Trader

Location:

Hongkong, China

Qualification:

Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Promethazine is used to prevent and treat nausea and vomiting related to certain conditions (such as before/after surgery, motion sickness). It is also used to treat allergy symptoms such as rash, itching, and runny nose. It may be used to help you feel sleepy/relaxed before and after surgery or to help certain narcotic pain relievers work better. It may also be used for a short time to treat a runny nose due to the common cold.

Product Name	Promethazine hydrochloride
CAS NO.	58-33-3
Other Name	promethazine hcl
Molecular Formular	C17H21ClN2S
Molecular Weight	320.880
Appearance	Crystalline powder
Purity	99%
Melting Point	230-232°C
Application	Pharmaceutical Intermediates
Density	1.131 g/cm3
Boiling Point	403.7ºC at 760 mmHg
Flash Point	198ºC

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Packing:

1. Weight <1kg ---- Fluorinated bottle

2. 25kg ---- Plastic bucket

3. 180- 200kg ---- Drum

P.S.: we accept packaging customization.

Delivery:

We have large quantity raw powder in stock, normally could ship out within 3 working days.
For rush delivery, please contact our sales team for particular arrangement.

Shipping:

We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg or even bulker.
Shipping details & shipping documents will be provided and sent to customers as long as it is ready.
We keep tracking the shippment until clients well received.
After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.

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Natrue is a high-end brand company focusing on the biomedical industry and integrating R&D, production and sales. It has an independent R&D center, advanced laboratory equipment and a professional R&D team, a GMP standard production workshop, a complete set of internationally advanced assembly line equipment, a preparation workshop with a cleanliness level of 100,000, as well as sophisticated testing instruments and scientific testing methods, providing solid technical support for the production of high-quality products. Through long-term R&D, production, and sales practices, it has formed its own unique product line, providing users with products of reliable quality at highly affordable prices. We strictly control quality, ensure the stability of product quality in all aspects, and win the trust of customers with high quality and high-level development.

Our team of experienced professionals is committed to delivering innovative solutions and exceptional customer service. We work closely with our clients to understand their unique needs and develop customized products to meet their specific requirements. With a state-of-the-art manufacturing facility and strict quality control measures, we ensure that our products meet the highest standards of safety and purity.

We have been keeping providing new products to the markets of Europe,America,Australia,Japan and South-east Asia,etc. We always insist on our company's principle or quality & credit are first"and after several years of development,we have enjoyed good reputation in the fitness industry.

We try our best to provide first-class goods,competitive price and supreme service to meet every client's requirements. We look forward to establish a long-term business relationship with you on the basis of equality and mutual benefits.

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Q1: Can I get a sample before placing an order?

A1: Yes, we can provide samples, you only need to pay the shipping fee and sample fee.

Q3: How long does it take to ship an order?

A3: We ship the package within 3-7 days with tracking number. Shipping times vary by country.

Q4: Why should you buy from us instead of other suppliers?

A4: Because we are a factory, we can provide lower prices and guaranteed quality. We have extensive experience in domestic and foreign trade and provide services in an honest, timely and efficient manner.

Q5: How to place an order for each product?

A5: Please send us an inquiry and let us know your requirements; we will send you a complete quotation including freight, confirm the order and send payment/deposit, we will arrange production or delivery of the goods after receiving the bank receipt.

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Basic Info

Product Name:

Promethazine hydrochloride

Other Name:

10H-Phenothiazine-10-ethanamine,N,N,α-trimethyl-,hydrochloride (1:1);Phenothiazine,10-[2-(dimethylamino)propyl]-,monohydrochloride;10H-Phenothiazine-10-ethanamine,N,N,α-trimethyl-,monohydrochloride;10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride;Plletia;Promethazine hydrochloride;Phenergan;Promethazine chloride;Promethazine monohydrochloride;Atosil;Fenergan;Diprazin;Pipolfen;Diprasine;Romergan;Pipolphen;Romergan hydrochloride;Kinetosin;Pyrethia;Promethazinium chloride;Phena;Promasun;Hiberna;Phencen;Dorme;Phenergan VC;Fellozine;Remsed;Lergigan;Genphen;Prorex;Fenazil;Anergan 25;Anergan 50;Duplamin;Prothazine;Mepergan;Provigan;Phanergan D;NSC 231688;Himazin;16639-38-6;88208-28-0

CAS No.:

58-33-3

Molecular Formula:

C17H20N2S.ClH

InChIKeys:

InChIKey=XXPDBLUZJRXNNZ-UHFFFAOYSA-N

Molecular Weight:

320.88

Exact Mass:

320.111389

EC Number:

200-375-2

NSC Number:

757301|231688

DSSTox ID:

DTXSID3021192

HScode:

2933699090

Categories:

Other Chemical Drugs

Characteristics

PSA:

31.8

XLogP3:

5.10640

Appearance:

Promethazine hydrochloride is an odorless white to faint yellow crystalline powder. Bitter taste. A 10% solution in water has a pH of 3.5-5.0. (NTP, 1992)

Density:

1.131 g/cm3

Melting Point:

230-232 °C

Boiling Point:

403.7ºC at 760 mmHg

Flash Point:

9℃

Water Solubility:

In water, 1.56X10-2 g/L (15.6 mg/L) at 24 deg C

Storage Conditions:

Refrigerator

Vapor Pressure:

1.03X10-5 mm Hg at 25 deg C (est)

Toxicity:

LD50 i.v. in mice: 55.0 mg/kg (Rajsner)

Collision Cross Section:

162.7 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Air and Water Reactions:

Slowly oxidizes in air, acquiring a blue color. Also turns blue on exposure to moisture. Water soluble.

Reactive Group:

Amines, Phosphines, and Pyridines

Reactivity Profile:

PROMETHAZINE HYDROCHLORIDE is sensitive to light. In aqueous solution, it is degraded by heat and light (more rapidly in air or oxygen). Incompatible with alkalis and alkaline solutions such as those of aminophylline, soluble barbiturates and phenytoin sodium. Iron(III) and copper(III) accelerate the degradation (NTP, 1992).

See More Promethazine hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Skin sensitization, Category 1

Eye irritation, Category 2

Acute toxicity - Category 4, Inhalation

Specific target organ toxicity â single exposure, Category 3

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H332 Harmful if inhaled H335 May cause respiratory irritation H411 Toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P317 Get medical help. P319 Get medical help if you feel unwell. P391 Collect spillage.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Promethazine hydrochloride preparations should be protected from light. Promethazine hydrochloride oral solution and tablets should be stored in tight, light-resistant containers at 15-30 and 20-25 deg C, respectively, while the rectal suppositories should be stored in well-closed containers at 2-8 deg C. Freezing of the oral solution should be avoided. Following the date of manufacture, commercially available promethazine preparations have expiration dates of 2-5 years depending on the dosage form and manufacturer.

See More Promethazine hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

Location:
Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$50 million-$100 million

Total Employees:
51-100

Year of Establishment:
2012

We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

"Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.

Inquiry History

13 Inquiries

Country	Product	Purchase Quantity	Date Posted
United Kingdom	Promethazine hydrochloride CAS 58-33-3 with High purity 99% White powder 58-33-3 SENYI	25 MT	Jun 17, 2023
Singapore	Promethazine hydrochloride CAS 58-33-3 with High purity 99% White powder 58-33-3 SENYI	1 KG	Jun 29, 2023
United States	Hot Selling CAS 58-33-3 Promethazine hydrochloride with 99% Purity White Powder	1 MT	Nov 6, 2023
Argentina	Promethazine hydrochloride	50 G	Apr 15, 2026
United Kingdom	Promethazine HCL 99.9% powder	1	Jan 10, 2026
United States	Promethazine Hydrochloride	20 G	Apr 10, 2025
Kenya	promethazine Hcl	40 KG	Dec 3, 2024
United States	Promethazine HCl	1	Jun 3, 2025
Canada	Promethazine hcl	1 KG	Jan 2, 2024
United States	Promethazine	1 KG	Jan 5, 2026
United States	USA UK Canada Europe etc 99% Pure Promethazine HCl Hydrochloride Powder CAS 58- 33-3 Safe Shipping	1 KG	Dec 14, 2025
Netherlands	Promethazine HCl	100 G	Mar 11, 2025
India	Promethazine Hydrochloride	25 G	Oct 9, 2024

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