BOC-Glycine 4530-20-5

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The company's main products include pharmaceutical intermediates, food additives, essence, spices and plant extracts. The products have passed international certification and are exported to Europe, America, Japan, South Korea and Southeast Asia.

BOC-Glycine Basic information

Product Name:	BOC-Glycine
Synonyms:	BOC-Glycine, 99+%;Boc-glycin;N-tert-Boc-glycine-OH;BOC-GLYCINE(N-TERT-BUTOXYCARBONYLGLYCINE);n-[(1,1-dimethylethoxy)carbonyl]-glycin;glycine(sterile);N-ALPHA-T-BUTYLOXYCARBONYL-GLYCINE;BOC-L-GLY-OH
CAS:	4530-20-5
MF:	C7H13NO4
MW:	175.18
EINECS:	224-864-5
Product Categories:	Intermediates & Fine Chemicals;Glycine [Gly, G];Amino Acids;Boc-Amino Acids and Derivative;Amino Acids 13C, 2H, 15N;Absolute Configuration Determination (Exciton Chirality CD Method);Amino Acids (N-Protected);Analytical Chemistry;Biochemistry;Boc-Amino Acids;Enantiomer Excess & Absolute Configuration Determination;Exciton Chirality CD Methodfor (for Monofunctional Compounds);Boc-Amino acid series;Amino Acids & Derivatives;Protected Amino Acids;AMINOACIDS DERIVATIVES;Amino Acid Derivatives;PROTECTED AMINO ACID & PEPTIDES;Pharmaceuticals
Mol File:	4530-20-5.mol

BOC-Glycine Chemical Properties

Melting point	86-89 °C(lit.)
Boiling point	306.47°C (rough estimate)
density	1.2843 (rough estimate)
refractive index	1.4353 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	4.00±0.10(Predicted)
form	Powder
color	White to off-white
Water Solubility	soluble
BRN	1101514
InChI	InChI=1S/C7H13NO4/c1-7(2,3)12-6(11)8-4-5(9)10/h4H2,1-3H3,(H,8,11)(H,9,10)
InChIKey	VRPJIFMKZZEXLR-UHFFFAOYSA-N
SMILES	C(O)(=O)CNC(OC(C)(C)C)=O
CAS DataBase Reference	4530-20-5(CAS DataBase Reference)
EPA Substance Registry System	Glycine, N-[(1,1-dimethylethoxy)carbonyl]- (4530-20-5)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	22-41-36/37/38-20/21/22
Safety Statements	26-36/37/39-39-36
RIDADR	UN2811
WGK Germany	3
TSCA	Yes
HazardClass	6.1
HS Code	29241990

MSDS Information

BOC-Glycine Usage And Synthesis

Chemical Properties	White To Off-White Powder
Uses	BOC-Glycine is used in the composition of drugs containing Ketoprofen, and Sodium hyaluronate as antiinflammatory agents.
Uses	Boc-Gly-OH can be used: For the esterification reaction to synthesize N-Boc amino acid esters for peptide chemistry. For the synthesis of tripeptide H-Gly-Pro-Glu-OH, analogs of neuroprotective drugs. As a promoter for the allylation of hydrazones and isatin.
Synthesis Reference(s)	Tetrahedron Letters, 16, p. 4393, 1975 DOI: 10.1016/S0040-4039(00)91133-X
reaction suitability	reaction type: Boc solid-phase peptide synthesis

First aid measures	General advice Consult a physician. Show this material safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Firefighting measures	Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special hazards arising from the substance or mixture Carbon oxides Nitrogen oxides (NOx) Advice for firefighters Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures	Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Environmental precautions Do not let product enter drains. Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.



——  Q&A  ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.