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cellulase CAS:9012-54-8

Name: cellulase CAS:9012-54-8
Brand: Orient
SKU: pr2512121428
Price: 4 USD
Availability: InStock

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CAS No.:

9012-54-8

Grade:

Industrial Grade

Content:

98%

Port:

SHANGHAI

Brand:

Orient

Packaging:

1KG, 25KG, 200KG, 1000KG, customized

Price valid (until):

2026-01-12

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Focusing on innovative research, development, and production in the field of fine chemicals, we prioritize technology, quality, and market orientation. We collaborate with global partners to build a high-tech chemical industry chain and promote sustainable development in the industry.

The company's main products include pharmaceutical intermediates, food additives, essence, spices and plant extracts. The products have passed international certification and are exported to Europe, America, Japan, South Korea and Southeast Asia.

Product Name:	cellulase
Synonyms:	Celluase;cellulasefromtrichodermalongibrachia-tum;qianweimeis;Fungalcellulase;1,4-[1,3:1,4]-BETA-D-GLUCAN;1,4-[1,3:1,4]-BETA-D-GLUCAN 4-GLUCANO-HYDROLASE;IUB: 3.2.1.4;MEICELASE
CAS:	9012-54-8
MF:	NULL
MW:	0
EINECS:	232-734-4
Product Categories:	Biochemistry;Enzyme;Glycohydrolase;Hydrolase;3.2.x.x Glycosidases;3.x.x.x Hydrolases;Application Index;Carbohydrate hydrolysis&PTM analysis;Carbohydrate HydrolysisEnzyme Class Index;9012-54-8
Mol File:	Mol File

cellulase Chemical Properties

density	1.2 g/mL at 25 °C
vapor pressure	0.004Pa at 25℃
storage temp.	2-8°C
solubility	deionized water: soluble5.0mg/mL (Sterile; In the presence of 0.15% polyhexamethylene biguanide (PHMB).)
form	powder
color	white
biological source	fungus (Trichoderma viride)
Water Solubility	Soluble in cold water.
Specific Activity	3-10units/mg solid
LogP	-1.3 at 20℃
EPA Substance Registry System	Cellulase (9012-54-8)

Safety Information

Hazard Codes	Xn,Xi
Risk Statements	42
Safety Statements	22-24-36/37-2-45-23
WGK Germany	1
RTECS	FJ5375000
F	3-10
TSCA	Yes
HS Code	35079090

MSDS Information

cellulase Usage And Synthesis

Brief Introduction	Cellulase naturally occurs in plant tissues; wherein it acts as a reinforcing material. It is thick and viscous in its physical arateristics, which makes it ideal for adding to foods and beverages to make ingredients combine and congealtogether. Cellulase is found in all plants and is quite abundant. Actually, it is the most widespread organic compound and is found in every habitat around the world. Its abundance and ease of acquisition make cellulase an ideal additive to foods and drinks, because it is cheap and easy to extract. Cellulase, as a nutrient, belongs to the category of roughage or fiber. Its binding properties make it popular among large-scale food and drink industries, who use it produce fruit juice, sparkling waters, spirits and other alcoholic beverages. When combined with other enzymes, cellulase is applied to produce wine; here its role is to extract foreign and unwanted substances from grape skins. In less quantities, cellulase is added as a congealant to washing and cleaning agents.
Chemical properties	It appears as off-white amorphous powder or liquid. It is soluble in water, almost insoluble in ethanol, chloroform and ether. It is relatively stable against heat. Even after being heated at 100 ℃ for 10min, it can still maintain 20% of the original activity. The general optimum temperature is 50~60 ℃, the optimum Ph value is 4.5~5.5.
Biological enzymes	Cellulase is a group of enzymes that catalyze the hydrolysis of cellulose to produce glucose and low polymerizing fibers, including three major components of dextran endonuclease, dextran exonuclease and cellobietase. It is not a single enzyme, but a synergistic multi-component enzyme system. Cellulase is an off-white powder or liquid. In 1906, Seilliere found the cellulase in the digestive solution of the snail. The cellulase hydrolyzes the β-1, 4-glucosidic linkages in the fibers to produce soluble polymers and D-glucose. Endocellulase breaks down internal bonds that it interrupts the cellulose’s crystalline structure, causing the exposure of cellulose polysaccharide chains. Exocellulase continues the process of endocellulase by breaking down the ends of the particular chains into maximum 4 units. That’s how disaccharides or tetrasaccharides like the cellobiose appear. Exocellulases were found in 2 forms: CBHII acts at the non-reducing cellulose end while the CBHI acts at the reducing end. Beta-glucosidase or cellobiase usually hydrolyses the above mentioned exocellulase and produces monosaccharides. The oxidative cellulase uses radical reactions like dehydrogenase and cellobiose to depolymerize cellulose. The activity of cellulase is commonly to split cellulose and convert it into beta-glucose. The symbiotic bacteria of herbivores produce this form of cellulase. Humans and other animals, besides ruminants, cannot generate this form of cellulase. Thus, they can split it only partially by using fermentation and they are not able to utilize the energy from the fibrous plants. According to the source of the enzyme, the relative molecular mass of the lowest 5000, up to 400000. The optimum pH is 4.0 to 5.0. The optimum temperature is 40~60 ℃. Some of the metal ions Mg2 +, Cl2 + and neutral salts can activate the enzyme, and some other metal ions Ag2 +, Cu2 +, Mn2 +, Hg2 + and dyes can inactivate the enzyme. The addition of cellulase to the wine can improve the saccharification effect and the liquor yield, and reduce the viscosity of the mash. Cellulase mainly comes from Aspergillus Niger and Trichoderma. Figure 1 the molecular structural formula of the cellulase
Source	The source of cellulase is very broad. Insects, mollusks, protozoa, bacteria, actinomycetes, fungi and so can all produce cellulase. 1. Bacteria: Bacteria produce a lower amount of cellulase, mainly EG, most of which are not active against crystalline cellulose, and the resulting enzyme is an intracellular enzyme or adsorbed on the bacterial wall and rarely secreted into the extracellular which increases the difficulty of extraction and purification. Therefore, in practice, bacteria are rarely used in industry. At present, more research focuses on the cellulose slime, Anoeba limax Duzardin and fibrobacter. 2. Actinomyces: Very few studies focus on actinomycetes. Mycobacterium and the original actinomycete produce almost no cellulase or have low yield; species produce a relatively high amount include black and red spin actinomycetes, rose actinomycetes, actinomycetes cellulosae and white rose actinomycetes. 3. Fungi: Current microorganisms used in the production of cellulase mostly belong to fungi with more studies focusing on Trichoderma, Aspergillus, Rhizopus and Peculiar mold. They can produce a large number of cellulase, especially for Trichoderma. Trichoderma reesei and Trichoderma viride are fungi with high enzyme activity in Trichoderma. The fungi can produce three types of cellulase, being able to be secreted into the bacteria. They generally don’t gather to form a multi-enzyme complex, but having a strong synergistic effect with each other. At present, its preparations include cellulase from Trichoderma viride, Aspergillus Niger, Fusariumsis, Paecilomyces and Penicillium decumbens and other cellulase. Microorganisms of the genera Trichoderma and Aspergillus are regarded to be cellulase producers, and crude enzymes produced by these microorganisms are commercially available for use in agriculture. Microorganisms of the genus Trichoderma produce comparatively large quantities of endo-ß-glucanase and exo-ß-glucanase, but only low levels of ß-glucosidase, while those of the genus Aspergillus produce comparatively large quantities of endo-ß-glucanase and ß-glucosidase with low levels of exo-ß-glucanase production. 4. Yeast: Due to the demand for industrial production of cellulase, it is required to increase enzyme production, exocrine and heat resistance. Recently, more and more research has been done on cellulase gene cloning. Although almost all of the cloned genes can be expressed in E. coli, but due to extraction difficulties and low level of expression, the current gene expression research has been transferred to the eukaryotic expression system. Yeast expression systems are mostly applied currently. Yeast does not produce toxins. Apply it for the expression of cellulase gene, the product is highly glycosylated. After correct processing and modification, it can be directly secreted into the medium with the expression level being high. For example, the yield of the CHB Ⅱ, EG Ⅰ expressed in yeast is up to 100mg/L or more, and has a normal biological activity.

First aid measures

General advice

Consult a physician. Show this material safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

Firefighting measures

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture

Carbon oxides Nitrogen oxides (NOx)

Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

Cellulase

Other Name:

Cellulase;E.C. 3.2.1.4;Endo-1,4-β-glucanase;β-1,4-Glucanase;Endocellulase;β-1,4-Endoglucan hydrolase;Cellzyme;Avicelase;Endo-β-1,4-glucanase;Pancellase SS;Endo-1,4-β-D-glucanase;Cellulysin;Celluclast 2.0L;Meicelase CEP;Cellulase A;Cellulosin AP;Onozuka R 10;Enzylon CA 40;Endoglucanase D;Celluclast 250L;Cooper cellulase;Maxazyme;SP 227;Macerozyme R 10;Meicelase CM 8B;Alkali cellulase;Cellulase A 3;Cellodextrinase;Zimet 43/803;Zimet 43/802;Zimet 43/804;Genencor 150L;Onozuka SS;Celluclast;Cellzyme 2400T;Spezyme FP 100;Meicelase;SP 359;Celluclast 2L;Cx-cellulase;Endoglucanase I;Cellulase K 344;Cellulase K 425;Endoglucanase 3;Celluzyme 1500T;Celluzyme;Avicelase I;Econase CE;1,4-β-D-Glucan endoglucanase;Onozuka RS;Onozuka P 500;1,4-β-D-Endoglucanase;β-1,4-Glycanase;Enchiron CM 10;Endoglucanase CelD;Endoglucanase E;Endoglucanase Z;Vesselex;Cellulase Y-NC;Onozuka FA;Endoglucanase E';Cellulase Cx;Cellulase Ononzuka 3S;Endoglucanase V;Cellulase TL 1000;EG III cellulase;Cellulase EG III;1,4-β-D-Glucan 4-glucanohydrolase;Maxazyme CL 2000;Endoglucanase K;Enzylon CM 10;Biocellulase;Cellulase YC;Cellulase ML;Celluclast 1.5L;β-1,4-D-Endoglucanase;Primafast 100;Pergalase A 40;Denimax T;Enzylon CM 40L;Godo TCL;Carezyme;Roglyr 1538;Rucolase;SP 424;SP 640;SP 431;Endoglucanase G;Celluzyme 0.7T;Enzylon CM 20L;Cellusoft;OP 8800;Hostazym C;Cellulyve Tr 300G;Cellulyve Tr 340G;Novozyme 342;9037-40-5;143296-48-4;145172-25-4;149718-64-9;152443-09-9;160995-61-9;179530-34-8;214975-89-0;881098-86-8;2242562-77-0

CAS No.:

9012-54-8

InChIKeys:

FYGDTMLNYKFZSV-CSHPIKHBSA-N

Molecular Weight:

504.4

Exact Mass:

504.169037

EC Number:

232-734-4

HScode:

35079090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

269

XLogP3:

-3.25

Appearance:

white powder

Density:

1.8±0.1 g/cm3

Boiling Point:

865.2±65.0 °C at 760 mmHg

Flash Point:

477.0±34.3 °C

Refractive Index:

1.673

Water Solubility:

soluble in cold water.deionized water: soluble 5.0mg/mL (Sterile; In the presence of 0.15% polyhexamethylene biguanide (PHMB).)

Storage Conditions:

2-8°C

See More Cellulase Properties 

Hazard Identification

Classification of the substance or mixture

Respiratory sensitization, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Prevention	P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P284 [In case of inadequate ventilation] wear respiratory protection.
Response	P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Cellulase Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

8 Inquiries

Country	Product	Purchase Quantity	Date Posted
Pakistan	BIO POLISH Enzyme	1 TON	Aug 24, 2023
Pakistan	BIO POLISH Enzyme	1 20' Fcl	Nov 7, 2023
United States	Alkaline cellulase (endo-1,4-β-glucanase)	50 KG	Dec 9, 2025
South Korea	Cellulase	100 G	Jun 9, 2025
Pakistan	BIO POLISH Enzyme for Textile Auxiliary FOR COTTON TEXTILE	1 20' Fcl	May 8, 2024
Kazakstan	Cellulase	1 MT	Aug 5, 2025
Bangladesh	Raw Biopolish Enzyme	2.00 MT	Apr 14, 2025
India	cellulase	5 MT	Nov 1, 2023

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