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Ascorbyl Palmitate CAS:137-66-6 C22H38O7

Name: Ascorbyl Palmitate CAS:137-66-6 C22H38O7
Brand: Orient
Price: 4 USD
Availability: InStock

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CAS No.:

137-66-6

Grade:

Industrial Grade

Content:

98%

Port:

SHANGHAI

Brand:

Orient

Packaging:

1KG, 25KG, 200KG, 1000KG, customized

Price valid (until):

2026-01-12

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Focusing on innovative research, development, and production in the field of fine chemicals, we prioritize technology, quality, and market orientation. We collaborate with global partners to build a high-tech chemical industry chain and promote sustainable development in the industry.

The company's main products include pharmaceutical intermediates, food additives, essence, spices and plant extracts. The products have passed international certification and are exported to Europe, America, Japan, South Korea and Southeast Asia.

Ascorbyl Palmitate Basic information

Product Name:	Ascorbyl Palmitate
Synonyms:	PALMITOYL L-ASCORBIC ACID;6-O-Palmitoyl ascorbate;Palmitoyl ascorbate;Ascorbyl Palmitate (2 g);Ascorbyl Palmitate (2 g) (AS);ASCORBYL PALMITATE(ASCORBIC ACID-6-PALMITATE)(P);Ascorbyl palMitate / 6-PalMitoylascorbic acid;VitaMin C Oil Soluble /L-Ascorbyl PalMitate
CAS:	137-66-6
MF:	C22H38O7
MW:	414.53
EINECS:	205-305-4
Product Categories:	Vitamin Ingredients;Vitamins and derivatives;Food & Feed ADDITIVES;Biochemistry;Sugar Acids;Food Additives;Sugars;Vitamin Derivatives;Vitamins;Vitamin series;EMPROVE;Inhibitors;137-66-6
Mol File:	137-66-6.mol

Ascorbyl Palmitate Chemical Properties

Melting point	115-118 °C(lit.)
alpha	+21～+26°(20℃/D, c=2, C2H5OH)
Boiling point	512.7±50.0 °C(Predicted)
density	1.150±0.06 g/cm3(Predicted)
refractive index	22.5 ° (C=1, EtOH)
storage temp.	2-8°C
solubility	Slightly soluble in ethyl alcohol.
pka	3.96±0.10(Predicted)
form	Solid
color	White to Pale Gray
Odor	wh. or yel.-wh. powd., citrus odor
Optical Rotation	[α]20/D +23±1°, c = 1% in ethanol
biological source	synthetic
BRN	96552
InChIKey	QAQJMLQRFWZOBN-UWJYYQICSA-N
LogP	6.5 at 30℃ and pH1.9
CAS DataBase Reference	137-66-6(CAS DataBase Reference)
EPA Substance Registry System	Ascorbyl palmitate (137-66-6)

Safety Information

Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38
Safety Statements	26-36-24/25
WGK Germany	1
RTECS	CI7671040
TSCA	Yes
HS Code	2936 27 00
Hazardous Substances Data	137-66-6(Hazardous Substances Data)
Toxicity	LD50 orally in Rabbit: > 5000 mg/kg

MSDS Information

Ascorbyl Palmitate Usage And Synthesis

Description	Ascorbyl palmitate is a lipophilic derivative of ascorbic acid with antioxidant and antiproliferative activities. It scavenges hydroxyl radicals in cell-free assays. Ascorbyl palmitate (0.01%) reduces the rate of autoxidation of soybean, safflower, sunflower, peanut, and corn oil. It inhibits increases in epidermal ornithine decarboxylase activity and DNA synthesis induced by phorbol 12-myristate 13-acetate (TPA; ) in mice in a concentration-dependent manner when applied topically. Ascorbyl palmitate (0.8 and 4 μmol per 200 μl of acetone, applied topically) reduces the number of tumors per mouse and the percentage of mice with tumors in a mouse skin two-stage model of tumor formation initiated and promoted by 7,12-dimethylbenz[a]anthracene (DMBA) and TPA, respectively. Formulations containing ascorbyl palmitate have been used as antioxidants and preservatives in foods, pharmaceuticals, and cosmetics.
Chemical Properties	Ascorbyl palmitate is a white or yellowish-white solid with a soapy taste and a citrus-like odor. It is very slightly soluble in water but freely soluble in alcohol, animal oil, and vegetable oil. It melts at 107° to 117°C (around 234°F). Ascorbyl palmitate prevents oxidative rancidity development by quenching singlet oxygen. The ascorbic acid part of the molecule donates hydrogen (a reducing agent). This phenomenon is also called "oxygen scavenging".
Uses	Ascorbyl Palmitate is an ester formed from ascorbic acid and palmitic acid creating a fat soluble form of vitamin C. It is used as an antioxidant food additive. It is also used as a preservative and an anti-oxidant in cosmetic creams and lotions to prevent rancidity. Ascorbyl palmitate facilitates the incorporation of ingredients such as vitamins A, C, and D into cosmetic formulations. It has no known toxicity.
Definition	ChEBI: Ascorbyl palmitate is a fatty acid ester. It is derived from corn dextrose fermentation and palm oil. It is used as a food preservative and as an antioxidant in oils, fats, and pharmaceuticals.
Production Methods	Ascorbyl palmitate is prepared synthetically by the reaction of ascorbic acid with sulfuric acid followed by reesterification with palmitic acid.
Application	Ascorbyl Palmitate is an antioxidant formed by combining ascorbic acid with palmitic acid. ascorbic acid is not fat soluble but ascorbyl palmitate is, thus combining them produces a fat-soluble antioxidant. it exists as a white or yellowish white powder of citric- like odor. it is used as a preservative for natural oils, edible oils, colors, and other substances. it acts synergistically with alpha-tocopherol in oils/fats. it is used in peanut oil at a maximum level of 200 mg/kg individually or in combination.
General Description	A white or yellowish-white powder having a citrus-like odor. Mp 116–117°C; soluble in alcohol and in animal and vegetable oils; slightly soluble in water. Ascorbyl Palmitate is a lipophilic ascorbic acid derivative, used as an antioxidant in both food and cosmetics industries.
Pharmaceutical Applications	Ascorbyl palmitate is primarily used either alone or in combination with alpha tocopherol as a stabilizer for oils in oral pharmaceutical formulations and food products; generally 0.05% w/v is used. It may also be used in oral and topical preparations as an antioxidant for drugs unstable to oxygen. The combination of ascorbyl palmitate with alpha tocopherol shows marked synergism, which increases the effect of the components and allows the amount used to be reduced. The solubility of ascorbyl palmitate in alcohol permits it to be used in nonaqueous and aqueous systems and emulsions.
Biochem/physiol Actions	6-O-Palmitoyl-L-ascorbic acid possesses metastasis inhibitory and anti-tumor activity. Ascorbyl palmitate exhibits antioxidant activity by protecting the cell membranes from oxidative damage.
Safety Profile	When heated to decomposition it emits acrid smoke and irritating fumes.
Safety	Ascorbyl palmitate is used in oral pharmaceutical formulations and food products, and is generally regarded as an essentially nontoxic and nonirritant material. The WHO has set an estimated acceptable daily intake for ascorbyl palmitate at up to 1.25 mg/kg bodyweight. LD₅₀ (mouse, oral): 25 g/kg LD₅₀ (rat, oral): 10 g/kg
storage	Ascorbyl palmitate is stable in the dry state, but is gradually oxidized and becomes discolored when exposed to light and high humidity. In an unopened container, stored in a cool place, it has a shelf life of at least 12 months. During processing, temperatures greater than 658℃ should be avoided. The bulk material should be stored in an airtight container at 8–158℃, protected from light.

First aid measures

General advice

Consult a physician. Show this material safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

Firefighting measures

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture

Carbon oxides Nitrogen oxides (NOx)

Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

Ascorbyl palmitate

Other Name:

L-Ascorbic acid,6-hexadecanoate;L-Ascorbic acid,6-palmitate;Palmitic acid,6-ester with ascorbic acid;Palmitoyl L-ascorbic acid;Ascorbyl palmitate;Ascorbylpalmitic acid;L-Ascorbyl palmitate;Ascorbyl monopalmitate;6-Monopalmitoyl-L-ascorbate;Ascorbic palmitate;6-O-Palmitoylascorbic acid;6-Palmitoylascorbic acid;Ascorbic acid palmitate;Cetyl ascorbate;Ondascora;Quicifal;L-Ascorbyl 6-palmitate;6-Hexadecanoyl-L-ascorbic acid;L-Ascorbyl monopalmitate;Ascorbyl 6-palmitate;Ascorboyl palmitate;Ascorbic acid 6-palmitate;6-Palmitate-L-ascorbic acid;6-O-Palmitoyl-L-ascorbic acid;6-O-Palmitoyl-L-ascorbic acid;NSC 402451;VCP 10;E 304;Vcpal;Grindox 562;AP;57233-83-7;120398-58-5;162872-43-7;924964-24-9;948551-42-6;1184913-60-7;2095286-71-6

CAS No.:

137-66-6

Molecular Formula:

C22H38O7

InChIKeys:

InChIKey=QAQJMLQRFWZOBN-LAUBAEHRSA-N

Molecular Weight:

414.53300

Exact Mass:

414.53

EC Number:

205-305-4

UNII:

QN83US2B0N

DSSTox ID:

DTXSID3041611

Color/Form:

White or yellowish white powder

HScode:

2932190090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

113.29000

XLogP3:

6.3

Appearance:

White to yellowish powder

Density:

1.15 g/cm3

Melting Point:

116 °C

Boiling Point:

512.7±50.0 °C(Predicted)

Flash Point:

178.1ºC

Refractive Index:

22.5 ° (C=1, EtOH)

Water Solubility:

Slightly soluble in ethyl alcohol.

Vapor Pressure:

3.32E-14mmHg at 25°C

Toxicity:

LD50 orally in Rabbit: > 5000 mg/kg

Odor:

Citrus-like

Henrys Law Constant:

Henry's Law constant = 1.40X10-7 atm-cu m/mol at 25 °C (est)

Collision Cross Section:

204.8 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Experimental Properties:

Weight/volume conversion: 16.92 mg/cu m approximately equal to 1 ppm|Base-catalyzed second-order hydrolysis reaction rate constant = 2.85X10-2 L/mol-sec at 25 °C (est)

See More Ascorbyl palmitate Properties 

Hazard Identification

Classification of the substance or mixture

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Ascorbyl palmitate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

8 Inquiries

Country	Product	Purchase Quantity	Date Posted
United Kingdom	High quality Ascorbyl Palmitate 99% White powder CAS NO. 137-66-6	5 KG	Aug 7, 2023
South Africa	Ascorbyl Palmitate	1 KG	Jul 2, 2025
Sri Lanka	Ascorbyl Palmitate	1000.00 KG	Feb 14, 2025
Argentina	Ascorbyl palmitate	1 MT	Dec 16, 2023
Sri Lanka	Ascorbyl Palmitate	100.00 KG	Feb 12, 2025
Pakistan	Ascorbyl palmitate	10 KG	Aug 5, 2024
Argentina	Ascorbyl Palmitate	10 KG	Aug 24, 2024
Egypt	Ascorbyl Palmitate	60 KG	Aug 22, 2024

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