5-methoxytryptamine/Pharmaceutical Grade | high Purity

5-Methoxytryptamine
Properties
Melting point
121-123 °C (lit.)
Boiling point
325.75°C (rough estimate)
Density
1.0815 (rough estimate)
Refractive index
1.5700 (estimate)
Storage condition
2-8°C
Solubility
Slightly soluble in chloroform and methanol
pKa
16.91±0.30(Predicted)
Form
Crystals
Color
White
Merck
13,6032
BRN
145587
InChI
InChI=1S/C11H14N2O/c1-14-9-2-3-11-10(6-9)8(4-5-12)7-13-11/h2-3,6-7,13H,4-5,12H2,1H3
InChIKey
JTEJPPKMYBDEMY-UHFFFAOYSA-N
SMILES
N1C2=C(C=C(OC)C=C2)C(CCN)=C1
CAS
608-07-1
Application & Synthesis
Application
5-Methoxytryptamine is a tryptamine derivative structurally related to neurotransmitters melatonin and serotonin. It acts as a full agonist for 5-HT1, 5-HT2, 5-HT4, 5-HT6 and 5-HT7 receptors, and shows no affinity to 5-HT3 receptor. It is designated as Melatonin USP Related Compound A.
Biological Activity
5-Methoxytryptamine (Mexamine) is a tryptamine derivative, serving as a full agonist of 5-HT1, 5-HT2, 5-HT4, 5-HT6 and 5-HT7 receptors.
Used as intermediate in organic synthesis
Intermediate for melatonin production
Safety Information
Hazard symbol
Xn
Risk Codes
22-36/37/38-20/21/22
Safety Statements
36-26
WGK Germany
3
RTECS
NL4110000
F
8
HS Code
29339900
Storage class
11 - Combustible solids
Hazard category
Acute toxicity, Category 4 (Oral)