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4-Hydroxyindole CAS: 2380-94-1

Name: 4-Hydroxyindole CAS: 2380-94-1
Brand: Orient
SKU: pr2512231376
Price: 4 USD
Availability: InStock

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CAS No.:

2380-94-1

Grade:

Industrail Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

1KG, 5KG, 25KG

Price valid (until):

2026-01-23

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Name:	4-Hydroxyindole
Synonyms:	4-Hdroxyindole;4-Hydroxyindole in stock Factory;1H-INDOL-4-OL;1H-INDOLE-4-OL;4-HYDROXY-1H-INDOLE;4-INDOLOL;4-HYDROXYINDOLE;INDOL-4-OL
CAS:	2380-94-1
MF:	C8H7NO
MW:	133.15
EINECS:	219-177-2
Product Categories:	API;Chemical;Indole;Indoles;Indole Derivatives;Heterocycle-Indole series;blocks;IndolesOxindoles;Indoles and derivatives;pharmacetical;Simple Indoles;Chiral Compound;Pyrroles & Indoles;Heterocycles;Heterocycles series;Pyrroles & Indoles;bc0001;2380-94-1
Mol File:	2380-94-1.mol

4-Hydroxyindole Chemical Properties

Melting point	97-99 °C(lit.)
Boiling point	245.66°C (rough estimate)
density	1.1475 (rough estimate)
vapor pressure	0.019Pa at 25℃
refractive index	1.5260 (estimate)
storage temp.	0-6°C
solubility	DMSO (Slightly), Methanol (Slightly)
pka	9.89±0.40(Predicted)
form	Solid
color	Dark Yellow to Green-Grey
Water Solubility	slightly soluble
Sensitive	Air Sensitive
BRN	114905
Cosmetics Ingredients Functions	HAIR DYEING
InChIKey	NLMQHXUGJIAKTH-UHFFFAOYSA-N
LogP	1.57 at 25℃
CAS DataBase Reference	2380-94-1(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-37/39
WGK Germany	3
Hazard Note	Irritant
HazardClass	IRRITANT, KEEP COLD
HS Code	29339900

MSDS Information

4-Hydroxyindole Usage And Synthesis

Chemical Properties	Off-White Cyrstalline Solid
Uses	4-Hydroxyindole is a Pindolol (P468000) impurity, which is a mixed adrenergic blocker and serotonin 5HT1A-receptor antagonist.
Definition	ChEBI: 4-hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole substituted by a hydroxy group at position 4. It is a member of phenols and a member of hydroxyindoles.
Application	4-Hydroxyindole as simple indoles is the important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers. It effectively inhibits Abeta peptide-induced amyloid fibril formation and prevent cell death induced by the peptide in culture. It is used for the synthesis of anti-inflammatory angular pyrrolocoumarins.
Preparation	Synthesis of 4-hydroxyindole: Using resorcinol as raw material, 4-oxotetrahydrocoumarone carboxylic acid is prepared by isomerization, catalytic hydrogenation, and cyclization with ethyl bromopyruvate. It was added to methanol solution saturated with ammonia, and the reaction was heated in an autoclave to generate 4-oxotetrahydroindole. Finally, 4-hydroxyindole is obtained by dehydrogenation and isomerization.
General Description	Glucouridination of 4-hydroxyindole by human uridine 5′-diphospho-glucuronosyltransferase has been repotrted.

First aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak. Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

1H-Indol-4-ol

Other Name:

1H-Indol-4-ol;Indol-4-ol;4-Hydroxyindole;4-Hydroxy-1H-indole

CAS No.:

2380-94-1

Molecular Formula:

C8H7NO

InChIKeys:

InChIKey=NLMQHXUGJIAKTH-UHFFFAOYSA-N

Molecular Weight:

133.15

Exact Mass:

133.15

EC Number:

219-177-2

UNII:

1W4VD9085V

DSSTox ID:

DTXSID3057696

HScode:

2933990090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

XLogP3:

2.4

Appearance:

Off-White Cyrstalline Solid

Density:

1.3±0.1 g/cm3

Melting Point:

100 °C

Boiling Point:

100 °C @ Press: 0.01 Torr

Flash Point:

161.4±20.4 °C

Refractive Index:

1.739

Water Solubility:

H2O: slightly soluble

Storage Conditions:

0-6ºC

Vapor Pressure:

0.000129mmHg at 25°C

See More 1H-Indol-4-ol Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Skin sensitization, Category 1

Serious eye damage, Category 1

Specific target organ toxicity â single exposure, Category 3

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H318 Causes serious eye damage H335 May cause respiratory irritation H411 Toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell. P391 Collect spillage.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 1H-Indol-4-ol Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

5 Inquiries

Country	Product	Purchase Quantity	Date Posted
Netherlands	4 hydroxy indole	1 KG	Jul 7, 2025
India	4-Hydroxyindole	100 KG	May 19, 2026
Netherlands	4 hydroxy indole	1 KG	Jul 3, 2025
United States	4-hydroxyindole	1 KG	Aug 17, 2024
Netherlands	4 hydroxy indole	1 KG	Jul 17, 2025

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