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Acetone oxime CAS:127-06-0

Name: Acetone oxime CAS:127-06-0
Brand: Orient
SKU: pr2512241506
Price: 4 USD
Availability: InStock

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CAS No.:

127-06-0

Grade:

Industrail Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

1KG, 5KG, 25KG

Price valid (until):

2026-01-24

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Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

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Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

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Product Description
Seller Information
Inquiry History

Description

Product Name:	Acetone oxime
Synonyms:	N-Isopropylidenehydroxylamine;N-Propan-2-ylidenehydroxylamine;propan-2-oneoxime;DI METHYL KETOXIME;LABOTEST-BB LT00516122;ACETOXIME;ACETONE OXIME;2-PROPANONE OXIME
CAS:	127-06-0
MF:	C3H7NO
MW:	73.09
EINECS:	204-820-1
Product Categories:	Imidazolines/Imidazolidines ,Imidazoles;Oximino Silanes;Pharmaceutical Intermediates;Nitrogen Compounds;Organic Building Blocks;Oximes;127-06-0
Mol File:	127-06-0.mol

Acetone oxime Chemical Properties

Melting point	60-63 °C(lit.)
Boiling point	135 °C(lit.)
density	0.901 g/mL at 25 °C(lit.)
vapor pressure	1.64-2.42hPa at 25℃
refractive index	1.4156
Fp	60 °C
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Sparingly), Methanol (Slightly)
pka	12.2(at 25℃)
form	Crystals or Crystalline Solid
color	White to yellow
Specific Gravity	0.901
Water Solubility	330 g/L (20 ºC)
Merck	14,75
BRN	1560146
Dielectric constant	3.0（-4℃）
InChIKey	PXAJQJMDEXJWFB-UHFFFAOYSA-N
LogP	0.077-0.2 at 22.7℃
CAS DataBase Reference	127-06-0(CAS DataBase Reference)
NIST Chemistry Reference	2-Propanone, oxime(127-06-0)
EPA Substance Registry System	Acetone oxime (127-06-0)

Safety Information

Safety Statements	22-24/25
RIDADR	UN1325
WGK Germany	3
RTECS	AL6825000
F	21
TSCA	Yes
HazardClass	4.1
PackingGroup	III
HS Code	29280000
Hazardous Substances Data	127-06-0(Hazardous Substances Data)
Toxicity	LD orl-rat: >500 mg/kg NCNSA6 5,26,53

MSDS Information

Acetone oxime Usage And Synthesis

Physical and Chemical Properties	Acetone oxime (Abbreviation DMKO for short), also known as dimethyl ketone oxime, is a white flaky crystal at room temperature, relative density: 0.9113, melting point: 60 ℃, flash point: 47.2 ℃, boiling point: 134.8 ℃, toxicity LD50: 5500mg/kg. It is soluble in water and alcohol, ether and other solvents, saturated aqueous solubility is 25% (mass percentage), its aqueous solution is neutral, it hydrolyzes easily in dilute acid, can make potassium permanganate fading at room temperature. Mainly used as chemical oxygen scavenger for industrial boiler feed water, compared with the traditional boiler chemical oxygen scavenger, it has characteristics of less dosage, high oxygen removal efficiency, non-toxic, pollution-free. It is the best drug for the outage protection and passivation treatment of subcritical boiler, also is the ideal products of substituted hydrazine and other traditional chemical oxygen scavengers in medium and high pressure boiler feed water. Figure 1 the molecular structure of Acetone oxime.
Chemical Properties	It is white needle-like crystal. Melting point is 61 ℃, boiling point is 136 ℃, 134.8 ℃ (97.1kPa), 61 ℃ (2.67kPa), the relative density is 0.9113 (62/4 ℃), refractive index is 1.4156. Easily soluble in water, ethanol, ether and acetone, soluble in acid, easily hydrolyzed in dilute acid. It volatilize in the air quickly.
Uses	1. Acetone oxime is used in organic synthesis, as an analytical reagent, used for the determination of cobalt. 2. Used as the intermediates of Caffeine, theophylline, SMD 3. Acetone oxime is used as test reagents for Chromium, used for organic synthesis, used as novel oxygen scavenger of boiler water, intermediates of medicine, pesticide. 4. It is used as raw materials of pharmaceutical, pesticide, dyes and organic silane coupling agent, can also be used as analytical reagent to identify nickel, cobalt, etc.
chemical reaction	Acetone oxime has a strong reduction, it is easy to react with oxygen in water to reduce the dissolved oxygen content in water, reaction is as follows: 2C3H7NO + O2 → 2C3H6CO + N2O + H2O and 4 (CH3) 2C = N-OH + O2 → 4 (CH3) 2C = O + 2N2 + H2O Meanwhile, Acetoxime also reacts with the metal for passivation, reaction is as follows: 2C3H7NO + 6Fe2O3 → 2C3H6CO + N2O + 4Fe3O4 + H2O Acetoxime can reduce the content of iron in the feed water, to prevent overheating of the metal pipe and corrosion damage of the boiler due to the formation of iron oxide deposits, while with the cleaning effect for copper corrosion products deposited on pipes, economizer, etc. This is the reason that in the early use of acetone oxime, the content of copper in boiler water will be significantly higher. Decomposition products of Acetoxime are mainly nitrogen and water, a small amount of formic acid, acetic acid, nitrogen oxides and so on. On the premise of ensuring oxygen removal effect, when the residual amount of DMKO in feed water is controlled to be 5~40μg/L, the formic acid, acetic acid, Cl-, SO42 + was not detected in all tested samples of water vapor, at the same time NO2-and NO3-content of same samples were tested, are also not detected. Therefore, there is no any adverse effects for the use of acetone oxime oxygen in vapor system.
Production method	It is obtained by the reaction of acetone with hydroxylamine hydrochloride. The hydroxylamine hydrochloride solution was slowly added dropwise in acetone, the reaction temperature is controlled at 40-50 ℃. The oximation reaction liquild was neutralized by 40% sodium hydroxide up to basic (pH7-8), cooling and filtration, the crude product was filtered off and add the zeolite, atmospheric distillation, cooling to obtain the finished product crystals.
Passivation agent after Boiler pickling	After the boiler pickling, the metal surface has high activity, it is necessary to use passivating agent to generate dense protective film on metal surfaces to prevent secondary corrosion of metal. Multi-hydrazine, sodium nitrite, sodium tripolyphosphate, etc, is conventionally used as passivating agent. Although the hydrazine and sodium pin Asia have a good passivation effect, but the drug itself has significant side effects to operators and users, it is difficult to handle passivation solution, and it pollutes the environment. Although Passivation method of sodium tripolyphosphate has advantages that its process is simple, liquid waste is easy to handle, but easily lead to the boiler water PH value lower after the unit started, bring some difficulties to control and process the water vapor quality. The experiment proved that replacement of the above passivating agents by acetone oxime (dimethyl ketone oxime) can obtain a satisfactory or better result. And it has the advantages of less dosage, emissions non-toxic pollution-free and so on. General passivation parameters: The concentration of Passivating agent: 8000-900mg/l PH value (ammonia tone) of passivation solution: 9.50-11 The temperature of purified fluid (atmospheric pressure cleaning system): 85-90 Purification Time: 14-18h

First aid measures

If inhaled

Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.

Following skin contact

Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.

Following eye contact

Rinse with pure water for at least 15 minutes. Consult a doctor.

Following ingestion

Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.

Accidental release measures

Personal precautions, protective equipment and emergency procedures

Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak. Environmental precautions

Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

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—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

Q4:What if there are quality issues？

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

Acetone, oxime

Other Name:

2-Propanone,oxime;Acetone,oxime;2-Propanone oxime;Acetoxime;β-Isonitrosopropane;Propanone oxime;Dimethyl ketoxime;N-Isopropylidenehydroxylamine;NSC 7601;Acetone oxime;Exkin 518

CAS No.:

127-06-0

Molecular Formula:

C3H7NO

InChIKeys:

InChIKey=PXAJQJMDEXJWFB-UHFFFAOYSA-N

Molecular Weight:

73.09

Exact Mass:

73.09

BRN:

1560146

EC Number:

204-820-1

UNII:

QX74TFD64T

NSC Number:

7601

DSSTox ID:

DTXSID6020010

Color/Form:

Columnar prisms|Colorless crystals

HScode:

2928000090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

32.6

XLogP3:

0.12

Appearance:

White to yellow Crystals or Crystalline Solid

Density:

0.9232 g/cm³ @ Temp: 804 °C

Melting Point:

61 °C

Boiling Point:

136 °C

Flash Point:

60 °C

Refractive Index:

1.410

Water Solubility:

H2O: 330 g/L (20 ºC)

Storage Conditions:

Keep container tightly closed in a dry and well-ventilated place.

Vapor Pressure:

1.82 mm Hg at 25 °C (242 hPa)

Toxicity:

Oral-rat LD50: >500 mg/kg; Abdominal cavity-mouse LD50:4000 mg/kg

Flammability characteristics:

Open flame is flammable; high-temperature separation liberates nitrogen oxide gas

Henrys Law Constant:

Henry's Law constant = 7.8X10-6 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

pK = 12.42 at 24.9 °C

Experimental Properties:

log Kow = 0.077 (Kow = 1.19) at 22.7 °C|Hydroxyl radical reaction rate constant = 3.3X10-13 cu cm/mole-sec at 25 °C (est)

See More Acetone, oxime Properties 

Hazard Identification

Classification of the substance or mixture

Flammable solids, Category 1

Acute toxicity - Category 4, Dermal

Skin sensitization, Sub-category 1B

Serious eye damage, Category 1

Carcinogenicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H228 Flammable solid H312 Harmful in contact with skin H317 May cause an allergic skin reaction H318 Causes serious eye damage H351 Suspected of causing cancer
Prevention	P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P240 Ground and bond container and receiving equipment. P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P203 Obtain, read and follow all safety instructions before use.
Response	P370+P378 In case of fire: Use ... to extinguish. P302+P352 IF ON SKIN: Wash with plenty of water/... P317 Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Acetone, oxime Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

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We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
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Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Acetone Oxime	1 MT	Jun 21, 2025

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