 Home > Active Pharmaceutical Ingredients > Diagnostic Agents > Methylene blue trihydrate for Sale > 99% Methylene Blue Trihydrate/Methylthioninium Chloride CAS:7220-79-3 Include Heavy Metals Test

99% Methylene Blue Trihydrate/Methylthioninium Chloride CAS:7220-79-3 Include Heavy Metals Test buy - large image1

99% Methylene Blue Trihydrate/Methylthioninium Chloride CAS:7220-79-3 Include Heavy Metals Test buy - image1

99% Methylene Blue Trihydrate/Methylthioninium Chloride CAS:7220-79-3 Include Heavy Metals Test buy - image2

99% Methylene Blue Trihydrate/Methylthioninium Chloride CAS:7220-79-3 Include Heavy Metals Test buy - image3

99% Methylene Blue Trihydrate/Methylthioninium Chloride CAS:7220-79-3 Include Heavy Metals Test buy - image4

99% Methylene Blue Trihydrate/Methylthioninium Chloride CAS:7220-79-3 Include Heavy Metals Test

Name: 99% Methylene Blue Trihydrate/Methylthioninium Chloride CAS:7220-79-3 Include Heavy Metals Test
Brand: HyperChem
SKU: pr2512291078
Price: 4 USD
Availability: InStock

TDS 4 Inquiries

Unit Price:

$4-5/G FOB

Get Latest Price 

CAS No.:

7220-79-3

Grade:

Pharmaceutical Grade

Content:

99.9%

Port:

Hangzhou

Brand:

HyperChem

Packaging:

100g/bag, 500g/bag;1kg/bags or other quantities

Price valid (until):

2027-04-30

Contact Supplier

 Chat Now

Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Name	Methylene Blue Trihydrate
CAS number	7220-79-3
Synonym	Methylene Blue trihydrate;7220-79-3; C.I. Basic Blue 9, trihydrate
Description	Methylene Blue Trihydrate, also known as Methylthioninium Chloride, with the CAS number 7220-79-3, is a well-known compound with a vast array of applications in the medical and scientific communities. This deep blue compound appears as a crystalline powder and has been used historically for multiple purposes ranging from a medication to a biological stain. Description Methylene Blue is a synthetic compound that belongs to the phenothiazine class of chemicals. It is highly soluble in water, which makes it a versatile agent for various applications. Its chemical structure is characterized by its tri-cationic form, commonly utilized in the tri-hydrated form to maintain stability and solubility in aqueous solutions. Mechanism of Action At the cellular level, Methylene Blue's primary mechanism of action involves its role as a redox agent. It acts as an electron donor or acceptor, which enables it to interfere with cellular processes that require electron transport. Specifically, in the field of medicinal use, Methylene Blue can inhibit the action of nitric oxide synthase and guanylate cyclase. This action has significant implications for treating conditions characterized by excessive nitric oxide production. Another notable mechanism of Methylene Blue is its use in the treatment of methemoglobinemia, a condition where the normal ferrous iron in hemoglobin is oxidized to the ferric state, reducing its oxygen-carrying capacity. Methylene Blue, via NADPH (nicotinamide adenine dinucleotide phosphate) pathway as a cofactor, helps to reduce methemoglobin back to hemoglobin, thus restoring its functionality in oxygen transport. Usage Methylene Blue is used in various fields like medicine, biology, and chemistry. In the medical domain, it functions as a medication for treating several conditions: Methemoglobinemia: As previously mentioned, by restoring hemoglobin's ability to bind oxygen, Methylene Blue is critical in reversing the symptoms of this life-threatening condition. Antimalarial treatments: Although not commonly used as a primary treatment, Methylene Blue can be used as part of combination therapy for malaria, demonstrating its diverse pharmacological profile. Urinary Antiseptic: It has mild antiseptic properties that are sometimes employed in treating urinary tract infections, although less frequently with the advent of more effective antibiotics. Diagnostic Agent: During surgery, Methylene Blue can be used to visually delineate anatomical regions or pathologic states such as certain types of tumors. It assists in lymph node mapping and sentinel lymph node biopsy. Psychiatric Investigations: There is ongoing research into the use of Methylene Blue as a treatment for conditions such as Alzheimer's disease, owing to its neuroprotective properties. In the field of biology, Methylene Blue serves as a vital stain used in various staining procedures. It is predominantly used in laboratories to stain animal tissues, making cellular organelles visible under a microscope, which aids in biological and pathological studies. Chemical Classification Chemically, Methylene Blue belongs to the class of compounds known as phenothiazines. The presence of multiple nitrogen and sulfur heterocycles in its structure classifies it among the heterocyclic compounds. This class is well-known for its diverse pharmacological and therapeutic properties, which is evident in the multifaceted uses of Methylene Blue. Additional Information Methylene Blue also finds applications in the field of aquaculture, particularly for the treatment of fungal infections in fish. Its antimicrobial properties aid in maintaining the health of aquatic species, further demonstrating its versatility. In recent years, there has been burgeoning interest in the potential antioxidative mechanism of Methylene Blue, which adds to its profile as a candidate in neuroprotective therapies. Studies are evaluating how its redox cycling can protect against neurodegenerative processes that underlie diseases like Alzheimer's and other cognitive disorders. It's important to note that while Methylene Blue offers many beneficial uses, careful dosing and administration are crucial given its ability to cause accumulation and toxicity at higher concentrations. Practitioners must adhere strictly to established guidelines to mitigate any adverse effects. In conclusion, Methylene Blue Trihydrate/Methylthioninium Chloride is a multifaceted compound with historical roots in chemistry and broad modern-day applications. From its therapeutic roles in medicine to its critical functions in the biological sciences, Methylene Blue continues to be an indispensable tool for researchers and healthcare professionals alike. As ongoing studies further elucidate its mechanisms and broaden its applications, its significance is expected to grow, making it an enduring component of scientific and medical advancements.

Molecular Formula	C ₁₆ H ₁₈ N ₃ S.Cl. ₃ H ₂ O
Molecular Weight	373.9 g/mol
Appearance	White or almost white crystalline powder
Quality Standard	USP EP
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 2~8 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Fiber drum
Origin	China

Shop USP Quality Standard API Finasteride Powder with CAS 98319-26-7-Detailed Image 2

Shop USP Quality Standard API Finasteride Powder with CAS 98319-26-7-Detailed Image 3

FAQ

Q1. What is the Hyper chem payment term?
T/T advance
LC at sight
DP at sight
Trade assurance
Money gram

Q2. What is Hyper chem shipment policy?
Our policy is to strive for the quickest shipment time possible, with ready stock sample shipment typically going out the same day that your order was placed. Your satisfaction is very important to us.
For non-ready stock, please contact the Hyper Chem sales team to negotiate.

Q3. What hyper chem will provide after shipment?
For sample orders:
After shipment is done, an timely email including:

Track details (Fedex /TNT/DHL/EMS Track number)

Package photo

COA, MSDS, etc

Dispatch date & Estimated arriving time

Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided
in scan-copy and original, to help customers complete the customs clearance process.

Q4. What is Hyper Chem shipment term?

By Express
DHL  FedEx  TNT  EMS
Fast:5 days around
High cost, door to door service

By Air
Suitable for more than 50kg
Fast :3-7 days Hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Slow:7-45 days, Low cost, port to port, professional broker needed
We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. Does hyper chem provide a shipment return policy?
Yes, we have.
Return Policy: At Hyper chem, your satisfaction is guaranteed. If you are dissatisfied for any reason with a product, please send back the unused portion along with your packing slip and a brief note on why you were dissatisfied within 45 days of purchase for a full refund to:

Q6. What is hyper chem After-sales service
• Documents support: COA ,MSDS, MOA ,MS Report,HNMR Report,SDS,DMF
• Customer Support: Shipment clearance support, quality issue support
• Automated Customer Service: Our worldwide customers enjoy immediate 24/7 access to the HYPER CHEM support team from any location, at any time.

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.

Certificates

Basic Info

Product Name:

Methylene blue trihydrate

Other Name:

Phenothiazin-5-ium,3,7-bis(dimethylamino)-,chloride,hydrate (1:1:3);C.I. Basic Blue 9,trihydrate;Phenothiazin-5-ium,3,7-bis(dimethylamino)-,chloride,trihydrate;3,7-Bis(dimethylamino)phenazathionium chloride trihydrate;Methylene blue trihydrate

CAS No.:

7220-79-3

Molecular Formula:

C16H18N3S.Cl.3H2O

InChIKeys:

InChIKey=XQAXGZLFSSPBMK-UHFFFAOYSA-M

Molecular Weight:

373.89800

Exact Mass:

373.12300

EC Number:

615-731-6

UNII:

T42P99266K

DSSTox ID:

DTXSID0025600

NCI Thesaurus Code:

C644

HScode:

32129000

Categories:

Diagnostic Agents

Characteristics

PSA:

75.07000

XLogP3:

-0.69000

Appearance:

Methylene blue trihydrate appears as odorless or almost odorless dark green crystals with bronze luster or dark green crystalline powder. pH (1% solution in water) 3 to 4.5 . (NTP, 1992)

Density:

0.98 g/mL at 25 °C

Melting Point:

190ºC

Flash Point:

14ºC

Water Solubility:

H2O: 4 g/100 mL

Storage Conditions:

Store at RT.

Vapor Pressure:

1.30X10-7 mm Hg at 25 deg C (est)

Air and Water Reactions:

Hygroscopic. Water soluble. Gives a blue solution in water.

Reactive Group:

Amines, Phosphines, and Pyridines

Reactivity Profile:

METHYLENE BLUE TRIHYDRATE is incompatible with strong oxidizing agents, caustics, alkali metal iodides and reducing agents. Also incompatible with dichromates. It forms double salts with many inorganic salts. Is bleached reversibly by (zinc + hydrochloric acid) or sodium hydrosulfite. In aqueous solution, this chemical is decolorized by zinc dust and dilute sulfuric acid, but the color is restored upon exposure to air and more rapidly upon addition of ammonium hydroxide. (NTP, 1992)

See More Methylene blue trihydrate Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Methylene blue trihydrate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

4 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Methylene blue	100 KG	Aug 26, 2024
India	Methylene blue trihydrate	100 KG	May 19, 2026
Pakistan	redox indicator	1 KG	Aug 19, 2025
United Kingdom	Methylene blue raw powder	1 MT	Sep 25, 2025

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
East Chem Methylene Blue trihydrate	/99		QINGDAO EAST CHEMSOURCES TRADE CO.,LTD	Inquiry
Methylthioninium Chloride 98% Supplement	Food Grade/98	$3000-3600/KG FOB	myland health	Inquiry
7220-79-3	/		Guangzhou Yaoguang Technology Co., Ltd.	Inquiry
CAS 7220-79-3 Pharmaceutical Grade Basic Blue 9	/		Shandong zhishang chemical Co.,Ltd	Inquiry
Wholesale Price 99% Methylene Blue Trihydrate Powder CAS 7220-79-3	Top Product/98	$10-11/KG FOB	Dingwang Technology (Wuhan) Co., Ltd.	Inquiry

99% Methylene Blue Trihydrate/Methylthioninium Chloride CAS:7220-79-3 Include Heavy Metals Test

Product Description

Seller Information

Inquiry History

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

Related Products

More Choices Find All Products for Sale 

Related Searches

Hot Related Products