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Promethazine hydrochloride powder API raw material powder 99% cas 58-33-3 With Best Price and Fast Delivery

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CAS No.:

58-33-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

qingdao

Brand:

Packaging:

Aluminium foil bag,25kg drum

Sample Available:

Yes

Price valid (until):

2026-02-06

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NATURE INDUSTRIAL LIMITED

Company Type:

Trader

Location:

Hongkong, China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

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Product Details
Seller Information
Inquiry History

Description

high quality Promethazine hydrochloride used to allergic diseases and Vomit CAS No.58-33-3

Product introduction

Product name:Promethazine hydrochloride
Synonyms: 10-(2-dimethylamino-1-propyl)phenothiazine hydrochloride;PROMETHAZINE HCL;PROMETHAZINE HYDROCHLORIDE;promethiazin
CAS: 58-33-3
MF: C17H21ClN2S
MW: 320.88
EINECS: 200-375-2
Promethazine hydrochloride
solubility Very soluble in water, freely soluble in ethanol (96 per cent) and in methylene chloride.
appearance: White to Almost white powder
Promethazine Uses
01.Antihistaminic, antiemetic, CNS depressant
02.stool softener
03.For the treatment of allergic disorders, and nausea/vomiting.
04.Promethazine hydrochloride is used as antihistamine; antiemetic; central nervous system depressant; antiserotoninergic; in the treatment of motion sickness, cough linctuses, nausea, and allergic conditions; used to control Parkinsonian symptoms and as central nervous system depressant.

Single impurity	≤ 0.5 %
Water	≤ 0.5 %
HPLC Purity	≥9 9 %

Product Description

Our company sells tons of API and intermeidates to domestic export trading companies every year.
In recent years, we have started to do foreign market. Please contact me to obtain the factory price.

Our services

♦ Competitive prices and high quality products

♦ A dequate inventory and products will be shipped out asap.

♦ Quick and clear response to customers questions.

♦ Comfortable conversation and easy talk

Items	Specifications
color	white to off white powder
purity	99%min

our Package

Shipping informationShipping information1g,1kg,5kg,10kg,25kg per package

Shipping information

our company

NATURE INDUSTRIAL LIMITED is a chemical company located in Jinan, Shandong Provincin Hongkong, China. The company was established in 20111 and has since grown to become a leading manufacturer and supplier of pharmaceutical intermediates, APIs, and other fine chemicals.

Quality is of the utmost importance to us The company has implemented a strict quality control system to ensure that all of its products meet or exceed the highest international standards. The company's quality control department is responsible for testing and analyzing each batch of products to ensure that they are of the highest quality.

NATURE INDUSTRIAL LIMITED is committed to environmental protection and sustainability. The company has implemented a comprehensive environmental management system that is in compliance with ISO 14001 standards. The company's production processes are designed to minimize waste and reduce the use of energy and other resources.

We are at exhibitions.We have established good cooerpation with customers from worldwide.

our lab

our company in exhibition

ECHEMI Editorial Reference

Promethazine Hcl(NSC-231688) is the first-generation antihistamine; strong antagonist of the H1 receptor and moderate mACh receptor antagonist, moderate affinity for 5-HT2A, 5-HT2C, D2 and α1-adrenergic receptors.
Promethazine hydrochloride is an odorless white to faint yellow crystalline powder. Bitter taste. A 10% solution in water has a pH of 3.5-5.0. (NTP, 1992)
Promethazine hydrochloride is an odorless white to faint yellow crystalline powder. Bitter taste. A 10% solution in water has a pH of 3.5-5.0. (NTP, 1992)|Promethazine hydrochloride is the hydrochloride salt of promethazine. It has a role as an antipruritic drug, a H1-receptor antagonist, a local anaesthetic, an antiemetic, a sedative, an anti-allergic agent, an anticoronaviral agent and a geroprotector. It contains a promethazine(1+).|A phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties. It is used as an antiallergic, in pruritus, for motion sickness and sedation, and also in animals.

Basic Info

Product Name:

Promethazine hydrochloride

Other Name:

10H-Phenothiazine-10-ethanamine,N,N,α-trimethyl-,hydrochloride (1:1);Phenothiazine,10-[2-(dimethylamino)propyl]-,monohydrochloride;10H-Phenothiazine-10-ethanamine,N,N,α-trimethyl-,monohydrochloride;10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride;Plletia;Promethazine hydrochloride;Phenergan;Promethazine chloride;Promethazine monohydrochloride;Atosil;Fenergan;Diprazin;Pipolfen;Diprasine;Romergan;Pipolphen;Romergan hydrochloride;Kinetosin;Pyrethia;Promethazinium chloride;Phena;Promasun;Hiberna;Phencen;Dorme;Phenergan VC;Fellozine;Remsed;Lergigan;Genphen;Prorex;Fenazil;Anergan 25;Anergan 50;Duplamin;Prothazine;Mepergan;Provigan;Phanergan D;NSC 231688;Himazin;16639-38-6;88208-28-0

CAS No.:

58-33-3

Molecular Formula:

C17H20N2S.ClH

InChIKeys:

InChIKey=XXPDBLUZJRXNNZ-UHFFFAOYSA-N

Molecular Weight:

320.88

Exact Mass:

320.111389

EC Number:

200-375-2

NSC Number:

757301|231688

DSSTox ID:

DTXSID3021192

HScode:

2933699090

Categories:

Inhibitor Drugs

Characteristics

PSA:

31.8

XLogP3:

5.10640

Appearance:

Promethazine hydrochloride is an odorless white to faint yellow crystalline powder. Bitter taste. A 10% solution in water has a pH of 3.5-5.0. (NTP, 1992)

Density:

1.131 g/cm3

Melting Point:

230-232 °C

Boiling Point:

403.7ºC at 760 mmHg

Flash Point:

9℃

Water Solubility:

In water, 1.56X10-2 g/L (15.6 mg/L) at 24 deg C

Storage Conditions:

Refrigerator

Vapor Pressure:

1.03X10-5 mm Hg at 25 deg C (est)

Toxicity:

LD50 i.v. in mice: 55.0 mg/kg (Rajsner)

Collision Cross Section:

162.7 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Air and Water Reactions:

Slowly oxidizes in air, acquiring a blue color. Also turns blue on exposure to moisture. Water soluble.

Reactive Group:

Amines, Phosphines, and Pyridines

Reactivity Profile:

PROMETHAZINE HYDROCHLORIDE is sensitive to light. In aqueous solution, it is degraded by heat and light (more rapidly in air or oxygen). Incompatible with alkalis and alkaline solutions such as those of aminophylline, soluble barbiturates and phenytoin sodium. Iron(III) and copper(III) accelerate the degradation (NTP, 1992).

See More Promethazine hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Skin sensitization, Category 1

Eye irritation, Category 2

Acute toxicity - Category 4, Inhalation

Specific target organ toxicity â single exposure, Category 3

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H332 Harmful if inhaled H335 May cause respiratory irritation H411 Toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P317 Get medical help. P319 Get medical help if you feel unwell. P391 Collect spillage.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Promethazine hydrochloride preparations should be protected from light. Promethazine hydrochloride oral solution and tablets should be stored in tight, light-resistant containers at 15-30 and 20-25 deg C, respectively, while the rectal suppositories should be stored in well-closed containers at 2-8 deg C. Freezing of the oral solution should be avoided. Following the date of manufacture, commercially available promethazine preparations have expiration dates of 2-5 years depending on the dosage form and manufacturer.

See More Promethazine hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

Location:
Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$50 million-$100 million

Total Employees:
51-100

Year of Establishment:
2012

We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

"Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.

Inquiry History

12 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Hot Selling CAS 58-33-3 Promethazine hydrochloride with 99% Purity White Powder	1 MT	Nov 6, 2023
United States	Promethazine hydrochloride	1 KG	Oct 8, 2026
Argentina	Promethazine hydrochloride	50 G	Apr 15, 2026
United Kingdom	Promethazine HCL 99.9% powder	1	Jan 10, 2026
United States	Promethazine Hydrochloride	20 G	Apr 10, 2025
Kenya	promethazine Hcl	40 KG	Dec 3, 2024
United States	Promethazine	1 KG	Jan 5, 2026
United States	USA UK Canada Europe etc 99% Pure Promethazine HCl Hydrochloride Powder CAS 58- 33-3 Safe Shipping	1 KG	Dec 14, 2025
Netherlands	Promethazine HCl	100 G	Mar 11, 2025
India	Promethazine Hydrochloride	25 G	Oct 9, 2024
United States	Promethazine HCl	1	Jun 3, 2025
Canada	Promethazine hcl	1 KG	Jan 2, 2024

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Promethazine hydrochloride powder API raw material powder 99% cas 58-33-3 With Best Price and Fast Delivery

Product Details

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