5-amino-1mq white powder cas 42464-96-0 Raw material powder 99% Purity Pharmaceutical Grade

Name:Nancy
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Email Address:nancy@xtdaxiang.cn

5-amino-1MQ   is a small molecule compound. As a selective inhibitor of nicotinamide N - methyltransferase (NNMT), it has demonstrated significant potential in various research areas related to metabolic regulation.

Core mechanism of action

Its core function is to inhibit the activity of the NNMT enzyme. This enzyme is highly expressed in adipose tissue and promotes nicotinamide methylation and decomposition, resulting in a reduction of intracellular coenzyme NAD⁺, thereby slowing down the metabolic rate.

After inhibiting NNMT, the intracellular NAD⁺ level can be maintained or even increased. NAD⁺ is a key cofactor involved in hundreds of metabolic processes such as ATP production and DNA repair. This change not only activates the longevity gene Sirtuin-1, facilitating the improvement of mitochondrial function, but also enhances fat breakdown and oxidation, reduces the volume of fat cells in white adipose tissue, and ultimately increases the metabolic rate.

Main research direction

Obesity and weight management: The experimental data from animals is impressive. For instance, when mice were given this compound for 10 days, their weight decreased by 7%. Additionally, studies have shown that it can reduce the weight of obese animals by 5.1%, decrease fat mass by 35%, and does not affect appetite. This provides a new direction for obesity research that does not rely on suppressing appetite.

Intervention for Metabolic Disorders: In the diet-induced obesity model, it can improve triglyceride levels, reduce liver fat content; at the same time, it can enhance insulin sensitivity, regulate blood sugar and cholesterol levels, and has significant reference value for the research of diseases such as type 2 diabetes and metabolic syndrome.

Muscle and Anti-Aging Research: In experiments, it can increase the grip strength of aged mice by approximately 40%, and also promote the regeneration of aging muscles. It has potential effects in delaying age-related muscle loss. Additionally, by activating longevity genes and improving mitochondrial function, it has become a research hotspot in the field of anti-aging.

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Company Profile

Daxiang Technology Co., Ltd., is a high-tech enterprise focusing on the research, development and production of peptide products. The company was established in recent years and is committed to applying advanced biotechnology to the health industry to meet the market's demand for high-quality, high-efficiency peptide products.​
As a leading peptide manufacturer, Daxiang Technology has a R&D team composed of senior scientists and engineers, which continues to explore and innovate, and is committed to developing safer, more effective, and more market-competitive peptide products. The company's main products cover but are not limited to pharmaceutical grade, food grade and cosmetic grade and other fields, and are widely used in many aspects such as health care, disease prevention, beauty and skin care.​
In terms of production technology, Daxiang Technology adopts internationally advanced production equipment and technology to ensure that every aspect of the product, from raw material selection, production and processing to finished product packaging, strictly follows relevant national standards and specifications to ensure product quality and safety. At the same time, the company has also established a complete quality management system and after-sales service system to provide customers with all-round, one-stop service support.​
Daxiang Technology adheres to the corporate philosophy of "technology leads health, quality creates the future" and always adheres to the development path of people-oriented and technological innovation. The company not only focuses on product quality and innovation, but also actively fulfills its social responsibilities and is committed to promoting the development and progress of the health industry.​
In the future,Daxiang Technology Co., Ltd. will continue to delve into the field of peptide product research and development, continue to explore and make breakthroughs, and strive to become a leader in the global peptide industry and make greater contributions to human health.