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Retatrutide Retatrutide safe delivery strong Lyophilized powder Vial

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CAS No.:

2381089-83-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Guangzhou

Brand:

Guangsheng

Packaging:

5-60mg*10vials

Price valid (until):

2026-02-14

Contact Supplier

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Guangsheng Technology co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

beaty prodt

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Name: Lynn
Wechat： 15914422644

Tel：+86 15914422644

Whatsapp: + 852 6252 8290

Email： guangsheng 5 @zgguangsheng.com

Product Detail

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1. Core Molecular & Physical Traits

Structure: 39-amino acid synthetic peptide with a lipid diacid moiety for extended half-life.
Formula/MW: C₂₂₃H₃₄₃F₃N₄₆O₇₀; 4845.44 Da.
Formulation: Subcutaneous injection (lyophilized powder), once-weekly dosing.
Pharmacokinetics: Half-life ~6 days; dose-proportional absorptionPubMed.
Purity: ≥99% (HPLC), ensuring high bioactivity.

2. Mechanism of Action (Triple Receptor Synergy)

Receptor	Key Actions
GLP-1R	Glucose-dependent insulin secretion; glucagon suppression; delayed gastric emptying; enhanced satiety
GIPR	Improved insulin sensitivity; lipid metabolism regulation; synergizes with GLP-1R for weight loss
GCGR	Boosts energy expenditure; reduces hepatic fat deposition; enhances lipolysis

Collectively, it curbs appetite, accelerates fat breakdown, improves glycemic control, and reduces liver fat.

3. Clinical Efficacy Data

Trial	Duration	Doses	Key Outcomes
Phase 2 (Obesity)	48 weeks	8/12 mg/week	Avg. weight loss: 24–28.7% (vs. ~15% for dual agonists)
Phase 3 (Triumph-4)	68 weeks	12 mg/week	Max. weight loss 28.7%; reduced knee pain by 75.8%
Type 2 Diabetes	24 weeks	4–12 mg/week	HbA1c ↓1.8–2.2%; fasting glucose ↓30–40 mg/dL
Hepatic Steatosis	24 weeks	8 mg/week	Liver fat content ↓40–50%

4. Safety & Tolerability

Common Side Effects: Mild–moderate, transient GI issues (nausea, diarrhea, vomiting).
Key Advantages: Low severe hypoglycemia risk (monotherapy); minimal impact on bone density/hormones.
Precautions: Avoid in medullary thyroid carcinoma, multiple endocrine neoplasia type 2, or hypersensitivity.

5. Application Scenarios

Obesity: Long-term weight management (adjunct to lifestyle changes).
Type 2 Diabetes: Adjunct therapy for glycemic control and weight reduction.
Metabolic Comorbidities: Non-alcoholic fatty liver disease (NAFLD), knee osteoarthritis (weight-related).
Future Potential: NASH, cardiovascular risk reduction, and body composition improvement.

6. Development Status

As of early 2026, it is in late-stage Phase 3 trials (e.g., TRIUMPH program). Eli Lilly plans to file for FDA approval in 2026, with potential launch in 2027.

Index	Standard	Test Method
Appearance	White to off-white lyophilized powder	Visual Inspection
Molecular Formula	C₂₂₁H₃₄₂N₄₆O₆₈	Mass Spectrometry
Molecular Weight	4731.33	Calculated & Verified by MS
Solubility	Soluble in water, dilute acid	Shake Test (25℃)Sterility
Sterility	Meets pharmaceutical R&D standards	Membrane Filtration Method

About Us

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Certificates

Basic Info

Product Name:

Retatrutide

Other Name:

LY3437943;Retatrutide;GIPR/GLP-1R;Retatrutide/LY3437943/GIPR/GLP-1R;Retaglutide;Retatrutide acetate;LY3437943Retatrutide;Retalutide

CAS No.:

2381089-83-2

Molecular Weight:

EC Number:

200-001-8

Color/Form:

White lyophilized

Categories:

Other Chemical Drugs

Characteristics

Water Solubility:

Soluble in water (5mg/ml).

Storage Conditions:

-20°C

Critical Temperature & Pressure:

-20°C

See More Retatrutide Properties 

Seller Information

Business Type:
Trader

Main Products:
beaty prodt

Location:
Yongtai Jinli City Plaza, Baiyun District, Guangzhou City, Guangdong Province

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
30

Total Annual Revenue:
Less than $1 million

Total Employees:
5-10

Year of Establishment:
2023

Inquiry History

5687 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Retatrutide 2381089-83-2	3 MT	Mar 28, 2026
United Kingdom	Retatrutide - 2381089-83-2	1 G	Feb 10, 2026
United States	Retatrutide CAS 2381089-83-2 10mg vial	20 MT	Mar 7, 2026
United States	Factory Retatrutide API 99% Purity CAS 2381089-83-2	5 KG	Nov 10, 2025
United Kingdom	Peptide powder Retatrutide 99% pure for Body building cas 2381089-83-2 Weight Loss Peptide with COA	1 MT	Mar 22, 2026
United States	2381089-83-2	100 G	Feb 24, 2026
United States	2381089-83-2	100 MT	Dec 9, 2023
United States	Retatrutide 2381089-83-2	200 MG	May 16, 2026
United Kingdom	2381089-83-2 retatrutide	300 MG	Feb 13, 2026
United States	Retatrutide 2381089-83-2 wholesale	500 MT	Nov 3, 2023
United States	Retatrutide CAS 2381089-83-2 99%	10 PCS	Feb 21, 2026
Poland	CAS 2381089-83-2 (Custom Peptide)	40 MT	Apr 10, 2026
Austria	Peptide Retatruide CAS 2381089-83-2	100 MT	Apr 4, 2026
Austria	Retatrutide CAS 2381089-83-2 10mg vial	20 PCS	Feb 10, 2026
United States	Tirzepatide 99.9% Liquid 2381089-83-2 TeruiOP	1 MT	Sep 6, 2023
United States	Retatrutide/LY3437943/GIPR/GLP-1R 98% Powder 2381089-83-2 Senwayer	1 G	Sep 3, 2023
United States	GLP-1 / GIP Retatrutide cas 2381089-83-2	1 MT	Oct 16, 2024
United States	Retatrutide 99% High Quality CAS 2381089-83-2	1 G	Jan 23, 2026
United States	Injection Peptide Tirzepatide/Retatrutide/ Semaglutide Peptides CAS 2381089-83-2	10	Oct 21, 2023
Palestine	Factory 99% Purity Retatrutide Peptide CAS 2381089-83-2 Door-To-Door Service	10 MG	Mar 16, 2026

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