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Glatiramer

Unit Price: Get Latest Price
CAS No.:

147245-92-9

Brand:

Hybio

Packaging:

/

Price valid (until):

2026-02-28

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Peptide,Polypeptides

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    Glatiramer is an immunomodulator used to reduce the frequency of relapses in Multiple Sclerosis (MS).


    Glatiramer acetate is a mix of synthetic polypeptides that includes L-glutamic acid, L-alanine, L-tyrosine, and L-lysine at an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. Since glatiramer acetate is a heterogeneous drug, there is limited information about its physicochemical properties. Originally, glatiramer acetate was designed as a stimulant of myelin basic protein (MBP), a myelin antigen involved in the development of multiple sclerosis (MS), to induce experimental autoimmune encephalitis (MS animal model). However, the opposite was observed. Glatiramer acetate exhibits several immunomodulatory effects and reduces the relapse rate of relapsing-remitting multiple sclerosis (RRMS) by 30%. Along with human interferon betateriflunomide, and dimethyl fumarate, glatiramer acetate is a first-line drug for patients with MS. It was approved by the FDA in 1996, and a generic version became available in 2017.

    Items Specifications
    Protein Chemical Formula

    (C5H9NO4•C3H7NO2•C6H14N2O2•C9H11NO3)x•xC2H4O2

    Protein Average Weight 7000.0 Da (Range 5000-9000)

    Basic Info
    Product Name:

    Glatiramer acetate

    Other Name:

    L-Glutamic acid,polymer with L-alanine,L-lysine and L-tyrosine,acetate (salt);L-Alanine,polymer with L-glutamic acid,L-lysine and L-tyrosine,acetate (salt);L-Lysine,polymer with L-alanine,L-glutamic acid and L-tyrosine,acetate (salt);L-Tyrosine,polymer with L-alanine,L-glutamic acid and L-lysine,acetate (salt);L-Glutamic acid peptide with L-alanine,L-lysine and L-tyrosine,acetate (salt);Cop 1;Cop 1 (polyamide);Glatiramer acetate;Copaxone;Copolymer 1;Protiramer;TV 5010;511: PN: WO2010103292 PAGE: 64 claimed sequence;Probioglat;Polimunol;Escadra;Natco;Hangzhou;Axoglatiran FS;Glatopa;M 356;943513-95-9

    CAS No.:

    147245-92-9

    Molecular Formula:

    (C9H11NO3.C6H14N2O2.C5H9NO4.C3H7NO2)x.xC2H4O2

    InChIKeys:

    InChIKey=FHEAIOHRHQGZPC-KIWGSFCNSA-N

    Molecular Weight:

    623.65

    Exact Mass:

    623.30100

    Characteristics
    PSA:

    374

    XLogP3:

    2.14760

    Boiling Point:

    385.2ºC at 760mmHg

    Flash Point:

    186.7ºC

    Vapor Pressure:

    1.27E-06mmHg at 25°C

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Skin sensitization, Sub-category 1B

    Eye irritation, Category 2

    Respiratory sensitization, Category 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H315 Causes skin irritation

    H317 May cause an allergic skin reaction

    H319 Causes serious eye irritation

    H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P284 [In case of inadequate ventilation] wear respiratory protection.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P333+P317 If skin irritation or rash occurs: Get medical help.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Peptide,Polypeptides

    Location:

    No.9, Linkong West Street, Hengdian Street, Huangpi District Wuhan, Hubei, China

    Total Employees:

    Above 1000

    Year of Establishment:

    2014

  • Country Product Purchase Quantity Date Posted
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