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Jinlan 98+ EP/BP/USP Vismodegib

Name: Jinlan 98+ EP/BP/USP Vismodegib
Brand: Jinlan
SKU: pr26012240677
Price: 129 USD
Availability: InStock

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CAS No.:

879085-55-9

Grade:

medical grade

Content:

98%

Port:

Shanghai/Ningbo/Qingdao

Brand:

Jinlan

Packaging:

25kg/Cardboard Drum

Sample Available:

Yes

Price valid (until):

2026-03-01

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Company Type:

Trader

Location:

China

Payment Terms:

100% TT in advance

Average Lead Time:

275 days

Qualification:

Main Products:

Peptides,API,Intermediate

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Product Details
Seller Information
Inquiry History

Description

Product Detail

Vismodegib (879085-55-9)

Basic Product Description

CAS Number: 879085-55-9

Chemical Name: 2-Chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide

Molecular Formula: C₁₉H₁₄Cl₂N₂O₃S

Molecular Weight: 421.30 g/mol

Synonyms: Erivedge®, GDC-0449

Related Categories: First-in-class Hedgehog Pathway Inhibitor, Oral Small Molecule Inhibitor, Smoothened (SMO) Receptor Antagonist, Basal Cell Carcinoma Therapeutic

Key Highlight: The first approved oral selective inhibitor of the Hedgehog signaling pathway by targeting the SMO receptor; indicated for the treatment of locally advanced and metastatic basal cell carcinoma (BCC) in adult patients; exerts anti-tumor effects by blocking the aberrantly activated Hedgehog pathway, which is critical for the growth and survival of BCC cells, with favorable oral bioavailability and a well-characterized safety profile for targeted therapy.

ECHEMI Editorial Reference

Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. It also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively.

Basic Info

Product Name:

Vismodegib

Other Name:

Benzamide,2-chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)-;2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide;GDC 0449;Vismodegib;Erivedge

CAS No.:

879085-55-9

Molecular Formula:

C19H14Cl2N2O3S

InChIKeys:

InChIKey=BPQMGSKTAYIVFO-UHFFFAOYSA-N

Molecular Weight:

421.303

Exact Mass:

421.30

EC Number:

1312995-182-4

HScode:

2933399090

Categories:

Other Chemical Drugs

Characteristics

PSA:

84.5

XLogP3:

3.8

Density:

1.4±0.1 g/cm3

Boiling Point:

561.6°C at 760 mmHg

Flash Point:

293.4±30.1 °C

Refractive Index:

1.641

Water Solubility:

In water, solubility is pH dependent wtih 0.1 mg/mL at pH 7 and 0.99 mg/mL at pH 11

Storage Conditions:

Store at room temperature 20 deg C to 25 deg C (68 deg F to 77 deg F); excursions permitted between 15 deg C to 30 deg C (59 deg F to 86 deg F)

Vapor Pressure:

7.6X10-14 mm Hg at 25 deg C (est)

See More Vismodegib Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Vismodegib Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Peptides,API,Intermediate

Location:
Room 606, Building 1, Fu Yi Commercial Center, Shangcheng District, Hangzhou City, Zhejiang Province - 1

Payment Terms:
100% TT in advance

Average lead Time:
275 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
51-100

Year of Establishment:
2020

Hangzhou Jinlan Pharm-Drugs Technology Co., Ltd (with its export company Hangzhou Royall Import & Export Co.,Ltd.) is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int' l Airport and Shanghai Pudong Int' l Airport, the transportation and production environment are excellent. JINLAN PHARMA mainly business includes: 1) API, Pharmaceutical Intermediates, CMO, CRO, CDMO and so on. 2) Pharmaceutical Equipment such as: Distilled Water Machinery, Mixer, Sterilizer and so on.

JINLAN PHARM focus on:

■ Contrast Agent

■ Anti-COVID APIs

■ Respiratory System APIs

■ Anti-tumor & Anti-Cancer APIs

■ Anti-Diabetes APIs

■ Anti-HCV & Anti-HBV APIs

■ Anti-HIV APIs

■ Peptides

■ Pharmaceutical Intermediates

■ CMO, CRO, CDMO

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Russia	Vismodegib	1 KG	Dec 21, 2024

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Jinlan 98+ EP/BP/USP Vismodegib

Product Details

Seller Information