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High-purity raw material Irinotecan CAS 97682-44-5 at competitive pricing

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Unit Price: Get Latest Price 

CAS No.:

97682-44-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Packaging:

1kg/bag;25kg/Cardboard Drum

Price valid (until):

2026-02-27

Contact Supplier

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Xi'an Honest BioEngr Co.,Ltd.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,100% TT in advance

Average Lead Time:

30 days

Qualification:

Main Products:

Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Superiority

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address

1.High quality and competitive price.
2.Free sample for your evaluation.
3.Promptly delivery by well-reputed shipping lines.
4.Trial order is available for testing after samples.
5.We will inform you all the information at every stage in advance.
6.Packaging can gear to buyers' special request.

Our service

1. Reply your inquiry in 24 working hours.
2. Customized design is available. OEM are welcomed.
3. Exclusive and unique solution can be provided to our customer by our well-trained and professional engineers and
staff.
4. Professional factory: We are manufacturer, specializing in producing all kinds of herb extract for more than 10 years, competitive with good quantity.
5. As an honest seller, we always use superior raw material, advanced machines, skilled technicians to ensure our products to be finished in high quality and stable feature.

Shop Guaranteed Smooth Customs Clearance for High-Purity Dutasteride (CAS 164656-23-9) at Competitive Prices-Detailed Image 1

FAQ

1.: Are you a factory or trading company
We are the integration of factory and trade.

2.: How is the quality I want to test.
Before production and extraction, we will test all raw materials.Quality is our top priority.All products are strictly tested and confirmed by our QC and QA, approved by Third Party Lab in China.So you will be assured with Good Quality if you choose us. We welcome you test the product and hope to get your feedback.

3.: Can I get a Free sample
Yes,We can provide free samples.For most products we can provide you a free sample, You only need to pay for Shipping. Plesae be free to consult our salesman.
For a larger quantity, we always support you with better price, and we will have some discount in some especial days.

4. : What's your main payment method
T/T (Bank transfer), Wechat,Alipay,Credit card payment.

5. : Have you received my payment How long will it take
Generally, we can receive your payment the next day, and we will inform you as soon as we receive your payment.
After confirmation payment, we will send out package

6.:When will you sent out the goods after successful payment
Normally the order will be delivery within 1-3 days after the order confirmed, except the customized products.

7.:What modes of transportation do you have to choose
We cooperate with HKEMS, DHL, TNT, UPS, FEDEX, EMS, China Air Post ,sea transportation etc.
And with the SAFE SHIPPING in each country, you can receive the goods smoothly.It is fast and safe method.

8.:How long does it take to the goods arrived
It is Depending on your location:
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, HKEMS,Netherlands post.
For large order, please allow 5-8 days by Air, 20-35 days by Sea
At the same time, we have warehouses in Germany and California, and some orders can be sent directly from Germany or California.

9.:How is the goods packed
We usually send goods with disguise package outside and a double-layer sterile transparent bag inside.We have tried thousand of package methods, it looks serious and discreet.

10.: How can I get a discount
Our products have already given you a discount, and the price is favorable. Orders above $1,000 can enjoy 95% discount, transportation discount or additional sample products. Therefore, for larger quantities, we always support better prices.

11.: How to proceed order
Please Let me konw the product you are looking for,quantity and the destination country wihch help me to give you a right price;
After you confirm all details of order, pay money in advance and give us Shipping address.We arrange the shipment at first time after receive payment and offer after-sales service after you receive parcel.

12.:When will I receive the shipping number Where I can check status of my order
After the goods are sent out, our staff will send you the shipping number via email, online or WhatsApp ASAP.You can also check the status online on 17track.

13.:Is a signature required for the shipping?
Our shipping method requires no signature from your side upon delivery.

ECHEMI Editorial Reference

Irinotecan is a water soluble topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex.
Solid
Irinotecan is a member of the class of pyranoindolizinoquinolines that is the carbamate ester obtained by formal condensation of the carboxy group of [1,4'-bipiperidine]-1'-carboxylic acid with the phenolic hydroxy group of (4S)-4,11-diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2- hydrochloride]quinoline-3,14-dione. Used (in the form of its hydrochloride salt trihydrate) in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active. It has a role as an apoptosis inducer, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, an antineoplastic agent and a prodrug. It is a pyranoindolizinoquinoline, a N-acylpiperidine, a carbamate ester, a tertiary alcohol, a tertiary amino compound, a delta-lactone and a ring assembly. It derives from a SN-38. It is a conjugate base of an irinotecan(1+).|Irinotecan is an antineoplastic enzyme inhibitor primarily used in the treatment of colorectal cancer. It is a derivative of camptothecin that inhibits the action of topoisomerase I. Irinotecan prevents religation of the DNA strand by binding to topoisomerase I-DNA complex, and causes double-strand DNA breakage and cell death. It is a derivative of camptothecin. Irinotecan was approved for the treatment of advanced pancreatic cancer in October, 2015 (irinotecan liposome injection, trade name Onivyde).|Irinotecan is a Topoisomerase Inhibitor. The mechanism of action of irinotecan is as a Topoisomerase Inhibitor.|Irinotecan and topotecan are semisynthetic derivatives of the plant alkaloid camptothecin and are used as antineoplastic agents in the therapy of colorectal, ovarian and non-small cell lung cancer. Both irinotecan and topotecan are associated with an appreciable rate of serum enzyme elevations during therapy, and irinotecan has been implicated in causing steatohepatitis when given as cyclic anticancer therapy.|A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS.

Basic Info

Product Name:

Irinotecan

Other Name:

[1,4′-Bipiperidine]-1′-carboxylic acid,(4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl ester;[1,4′-Bipiperidine]-1′-carboxylic acid,4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl ester,(S)-;1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline,[1,4′-bipiperidine]-1′-carboxylic acid deriv.;Irinotecan;(+)-Irinotecan;Irinotecan lactone;Irinophore C;Irinotecan mylan;(19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0[2,11].0[4,9].0[15,20]]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl 4-(piperidin-1-yl)piperidine-1-carboxylate

CAS No.:

97682-44-5

Molecular Formula:

C33H38N4O6

InChIKeys:

InChIKey=UWKQSNNFCGGAFS-XIFFEERXSA-N

Molecular Weight:

623.14

Exact Mass:

586.68

EC Number:

1806241-263-5

UNII:

7673326042

NSC Number:

728073

DSSTox ID:

DTXSID1041051

Color/Form:

Pale yellow powder

ATC Code:

L01XX19|L - Antineoplastic and immunomodulating agents

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

113

XLogP3:

Appearance:

Solid

Density:

1.4±0.1 g/cm3

Melting Point:

222-223 °C

Flash Point:

482.0±34.3 °C

Refractive Index:

1.689

Water Solubility:

1.07e-01 g/L

Storage Conditions:

2-8°C

Experimental Properties:

Pale yellow to yellow crystalline powder. MW: 677.19. Slightly soluble in water and organic solvents /Hydrochloride/

See More Irinotecan Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Serious eye damage, Category 1

Reproductive toxicity, Category 2

Specific target organ toxicity â repeated exposure, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H318 Causes serious eye damage H361 Suspected of damaging fertility or the unborn child H373 May cause damage to organs through prolonged or repeated exposure
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P203 Obtain, read and follow all safety instructions before use. P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P317 Get medical help. P318 IF exposed or concerned, get medical advice. P319 Get medical help if you feel unwell.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Irinotecan Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10

Location:
XINYUAN DADUHUI PHASE 1, NO.258 TAOYUAN NORTH ROAD, LIANHU DISTRICT, XI 'AN , SHAANXI CHINA

Payment Terms:
TT against copy of documents,100% TT in advance

Average lead Time:
30 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
11-50

Year of Establishment:
2023

Company Profile

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	irinotecan	1 MT	Feb 9, 2024

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High-purity raw material Irinotecan CAS 97682-44-5 at competitive pricing

Product Description

Seller Information