High-purity raw material Riluzole CAS 1744-22-5 at competitive pricing
1744-22-5
Pharmaceutical Grade
99%
shanghai
1kg/bag;25kg/Cardboard Drum
2026-02-28
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceRiluzole is an anticonvulsant drug and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.
Solid
Riluzole is a member of benzothiazoles.|A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.|Riluzole is a Benzothiazole.|Riluzole is a neuroprotective agent used for therapy of amyotrophic lateral sclerosis. Riluzole is associated with a low rate of serum aminotransferase elevations during therapy and has been linked to rare instances of clinically apparent, acute liver injury.|Riluzole is a benzothiazole derivative with neuroprotective and potential anti-depressant and anxiolytic activities. While the mechanism of action of riluzole is unknown, its pharmacological activities in motor neurons include the following, some of which may be related to its effect: 1) an inhibitory effect on glutamate release, 2) inactivation of voltage-dependent sodium channels, and 3) interference with intracellular events that follow transmitter binding at excitatory amino acid receptors. In animal models, this agent has been shown to exhibit myorelaxant and sedative activities, apparently due to the blockade of glutamatergic neurotransmission.|A glutamate antagonist (RECEPTORS, GLUTAMATE) used as an anticonvulsant (ANTICONVULSANTS) and to prolong the survival of patients with AMYOTROPHIC LATERAL SCLEROSIS.Basic Info-
Product Name:
Riluzole
Other Name:2-Benzothiazolamine,6-(trifluoromethoxy)-;Benzothiazole,2-amino-6-(trifluoromethoxy)-;6-(Trifluoromethoxy)-2-benzothiazolamine;2-Amino-6-(trifluoromethoxy)benzothiazole;PK 26124;Riluzole;RP 54274;6-(Trifluoromethoxy)-2-aminobenzothiazole;Rilutek;6-(Trifluoromethoxy)-1,3-benzothiazol-2-ylamine;6-Trifluoromethoxybenzothiazol-2-ylamine;6-(Trifluoromethoxy)-1,3-benzothiazol-2-amine;6-Trifluoromethoxybenzo[d]thiazol-2-amine;Rilutor;BHV 0233
CAS No.:1744-22-5
Molecular Formula:C8H5F3N2OS
InChIKeys:InChIKey=FTALBRSUTCGOEG-UHFFFAOYSA-N
Molecular Weight:234.2
Exact Mass:234.20
EC Number:1592732-453-0
UNII:7LJ087RS6F
NSC Number:759823|753433
DSSTox ID:DTXSID3045192
NCI Thesaurus Code:C47704
ATC Code:N07XX02|N - Nervous system
HScode:2934999090
Categories:
Characteristics-
PSA:
76.4
XLogP3:3.6
Appearance:white solid
Density:1.6±0.1 g/cm3
Melting Point:117-119 °C
Boiling Point:296.3°C at 760 mmHg
Flash Point:133.0±30.1 °C
Refractive Index:1.615
Water Solubility:DMSO: ≥25 mg/mL
Storage Conditions:Store at RT
Vapor Pressure:0.00145mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Location:
XINYUAN DADUHUI PHASE 1, NO.258 TAOYUAN NORTH ROAD, LIANHU DISTRICT, XI 'AN , SHAANXI CHINA
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Payment Terms:
TT against copy of documents,100% TT in advance
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Average lead Time:
30 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2023
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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