Setipiprant RC01169
1 Inquiries
866460-33-5
Pharmaceutical Grade
99%
Royalchem
25kg/drum
Yes
2029-12-31
Pharmaceutical intermediates
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceSetipiprant is an orally available, selective CRTH2 antagonist. CRTH2 is a G protein-coupled receptor for PGD2.IC50 value: 6.0 nMTarget: PGD2in vitro: Setipiprant is an orally available, selective CRTH2 (chemoattractant receptor-homologous molecule expressed on T helper [Th]-2 cells) antagonist. CRTH2 is a G protein-coupled receptor for prostaglandin (PGD2). PGD2 is produced by the mast cells and is a key mediator in various inflammatory diseases, including allergy and asthma. Binding of
Setipiprant is a naphthalenecarboxamide.|Setipiprant has been investigated for the treatment of Seasonal Allergic Rhinitis.Basic Info-
Product Name:
Setipiprant
Other Name:5H-Pyrido[4,3-b]indole-5-acetic acid,8-fluoro-1,2,3,4-tetrahydro-2-(1-naphthalenylcarbonyl)-;8-Fluoro-1,2,3,4-tetrahydro-2-(1-naphthalenylcarbonyl)-5H-pyrido[4,3-b]indole-5-acetic acid;Setipiprant;ACT 129968;2-(2-(1-Naphthoyl)-8-fluoro-1,2,3,4-tetrahydropyrido[4,3-b]indol-5-yl)acetic acid;1263765-62-3
CAS No.:866460-33-5
Molecular Formula:C24H19FN2O3
InChIKeys:InChIKey=IHAXLPDVOWLUOS-UHFFFAOYSA-N
Molecular Weight:402.425
Exact Mass:402.42
UNII:BHF20LA2GM
DSSTox ID:DTXSID00235739
Categories:
Characteristics-
PSA:
62.5
XLogP3:3.39
Appearance:Light yellow to yellow solid
Density:1.4±0.1 g/cm3
Boiling Point:690.4±55.0 °C at 760 mmHg
Flash Point:371.4±31.5 °C
Refractive Index:1.682
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
United Kingdom
Setipiprant
100 G Sep 22, 2026 Post an enquiry for this product
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