Zoledronic acid hydrate RC08938
165800-06-6
Pharmaceutical Grade
99%
Royalchem
25kg/drum
Yes
2030-01-01
Pharmaceutical intermediates
-
Product Description
-
Seller Information
-
DescriptionECHEMI Editorial ReferenceZoledronic Acid is a synthetic imidazole bisphosphonate analog of pyrophosphate with anti-bone-resorption activity. A third-generation bisphosphonate, zoledronic acid binds to hydroxyapatite crystals in the bone matrix, slowing their dissolution and inhibiting the formation and aggregation of these crystals. This agent also inhibits farnesyl pyrophosphate synthase, an enzyme involved in terpenoid biosynthesis. Inhibition of this enzyme prevents the biosynthesis of isoprenoid lipids, donor substrates of farnesylation and geranylgeranylation during the post-translational modification of small GTPase signalling proteins, which are important in the process of osteoclast turnover. Decreased bone turnover and stabilization of the bone matrix contribute to the analgesic effect of zoledronic acid with respect to painful osteoblastic lesions. The agent also reduces serum calcium concentrations associated with hypercalcemia.|An imidobisphosphonate inhibitor of BONE RESORPTION that is used for the treatment of malignancy-related HYPERCALCEMIA; OSTEITIS DEFORMANS; and OSTEOPOROSIS.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standardsBasic Info-
Product Name:
Zoledronic acid hydrate
Other Name:[1-HYDROXY-(1H-IMIDAZOL-1-YL)-PHOSPHONOETHYL] PHOSPHONIC ACID MONOHYDRATE;(1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid hydrate;(1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid monohydrate;PHOSPHONIC ACID, [1-HYDROXY-2-(1H-IMIDAZOL-1-YL)ETHYLIDENE]BIS-, MONOHYDRATE;zoledronic acid hydrate;ZOLEDRONIC ACID MONOHYDRATE;ZoledronicacidforInjection;[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) monohydrate
CAS No.:165800-06-6
Molecular Formula:C5H12N2O8P2
InChIKeys:FUXFIVRTGHOMSO-UHFFFAOYSA-N
Molecular Weight:290.1
Exact Mass:290.00688934
UNII:6XC1PAD3KF
DSSTox ID:DTXSID10168029
NCI Thesaurus Code:C1699
Color/Form:white to beige
ATC Code:M05BA08
HScode:29332900
Categories:
Characteristics-
Melting Point:
245 °C(dec.)
Water Solubility:H2O: ≥2mg/mL
Critical Temperature & Pressure:2-8°C
-
-
Seller Information
-
Business Type:
Trader
-
Main Products:
Pharmaceutical intermediates
-
Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
-
Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
-
Average lead Time:
14 days
-
Total Annual Revenue:
Less than $1 million
-
Total Employees:
Less than 5
-
Year of Establishment:
2025
-
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product
More from this Seller
-
-
![3-Benzyloxybenzyl bromide RC09132]( "3-Benzyloxybenzyl bromide RC09132")
-
3-Benzyloxybenzyl bromide RC09132
Industrial Grade / 99%
$1/KG EXW
-
-
-
![Ammonium hexafluorotitanate RC09122]( "Ammonium hexafluorotitanate RC09122")
-
Ammonium hexafluorotitanate RC09122
Industrial Grade / 99%
$1/KG EXW
-
-
-
![Potassium (benzyloxycarbonylamino)methyltrifluoroborate RC09116]( "Potassium (benzyloxycarbonylamino)methyltrifluoroborate RC09116")
-
Potassium (benzyloxycarbonylamino)methyltrifluoroborate RC09116
Industrial Grade / 99%
$1/KG EXW
-
-
-
![Dibenzoyl-D-tartaric acid(D-DBTA) RC09139]( "Dibenzoyl-D-tartaric acid(D-DBTA) RC09139")
-
Dibenzoyl-D-tartaric acid(D-DBTA) RC09139
Pharmaceutical Grade / 99%
$1/KG EXW
-
-
-
![Hydrogen tetrachloroaurate(III) trihydrate RC09121]( "Hydrogen tetrachloroaurate(III) trihydrate RC09121")
-
Hydrogen tetrachloroaurate(III) trihydrate RC09121
Industrial Grade / 99%
$1/KG EXW
-
-
-
![Bis(4-aminophenyl)terephthalate (BAPT) RC09100]( "Bis(4-aminophenyl)terephthalate (BAPT) RC09100")
-
Bis(4-aminophenyl)terephthalate (BAPT) RC09100
Industrial Grade / 99%
$1/KG EXW
-
