OLEDRONIC ACID MONOHYDRATE
165800-06-6
Tech Grade
99%
DAHAI BIOCHEM
25kg/Drum
2026-10-03
HARD FAT
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceZoledronic Acid is a synthetic imidazole bisphosphonate analog of pyrophosphate with anti-bone-resorption activity. A third-generation bisphosphonate, zoledronic acid binds to hydroxyapatite crystals in the bone matrix, slowing their dissolution and inhibiting the formation and aggregation of these crystals. This agent also inhibits farnesyl pyrophosphate synthase, an enzyme involved in terpenoid biosynthesis. Inhibition of this enzyme prevents the biosynthesis of isoprenoid lipids, donor substrates of farnesylation and geranylgeranylation during the post-translational modification of small GTPase signalling proteins, which are important in the process of osteoclast turnover. Decreased bone turnover and stabilization of the bone matrix contribute to the analgesic effect of zoledronic acid with respect to painful osteoblastic lesions. The agent also reduces serum calcium concentrations associated with hypercalcemia.|An imidobisphosphonate inhibitor of BONE RESORPTION that is used for the treatment of malignancy-related HYPERCALCEMIA; OSTEITIS DEFORMANS; and OSTEOPOROSIS.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standardsBasic Info-
Product Name:
Zoledronic acid hydrate
Other Name:[1-HYDROXY-(1H-IMIDAZOL-1-YL)-PHOSPHONOETHYL] PHOSPHONIC ACID MONOHYDRATE;(1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid hydrate;(1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid monohydrate;PHOSPHONIC ACID, [1-HYDROXY-2-(1H-IMIDAZOL-1-YL)ETHYLIDENE]BIS-, MONOHYDRATE;zoledronic acid hydrate;ZOLEDRONIC ACID MONOHYDRATE;ZoledronicacidforInjection;[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) monohydrate
CAS No.:165800-06-6
Molecular Formula:C5H12N2O8P2
InChIKeys:FUXFIVRTGHOMSO-UHFFFAOYSA-N
Molecular Weight:290.1
Exact Mass:290.00688934
UNII:6XC1PAD3KF
DSSTox ID:DTXSID10168029
NCI Thesaurus Code:C1699
Color/Form:white to beige
ATC Code:M05BA08
HScode:29332900
Categories:
Characteristics-
Melting Point:
245 °C(dec.)
Water Solubility:H2O: ≥2mg/mL
Critical Temperature & Pressure:2-8°C
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Seller Information
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Business Type:
Trader
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Main Products:
HARD FAT
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Location:
BUILDING 4,NO.571, STR.19,BAIYANG DISTRICT, HANGZHOU,CHINA
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance
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Total Annual Revenue:
Less than $1 million
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Total Employees:
5-10
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Year of Establishment:
2025
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