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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Zoledronic acid hydrate for Sale > Zoledronic Acid Monohydrate CAS 165800-06-6 Potent Bisphosphonate for Bone Metabolism and Osteoporosis Research hfd
Zoledronic Acid Monohydrate CAS 165800-06-6 Potent Bisphosphonate for Bone Metabolism and Osteoporosis Research  hfd buy - large image1
Zoledronic Acid Monohydrate CAS 165800-06-6 Potent Bisphosphonate for Bone Metabolism and Osteoporosis Research  hfd buy - image1
Zoledronic Acid Monohydrate CAS 165800-06-6 Potent Bisphosphonate for Bone Metabolism and Osteoporosis Research  hfd buy - image2
Zoledronic Acid Monohydrate CAS 165800-06-6 Potent Bisphosphonate for Bone Metabolism and Osteoporosis Research  hfd buy - image3
Zoledronic Acid Monohydrate CAS 165800-06-6 Potent Bisphosphonate for Bone Metabolism and Osteoporosis Research  hfd buy - image4
Zoledronic Acid Monohydrate CAS 165800-06-6 Potent Bisphosphonate for Bone Metabolism and Osteoporosis Research  hfd buy - image5
Zoledronic Acid Monohydrate CAS 165800-06-6 Potent Bisphosphonate for Bone Metabolism and Osteoporosis Research  hfd buy - image6

Zoledronic Acid Monohydrate CAS 165800-06-6 Potent Bisphosphonate for Bone Metabolism and Osteoporosis Research hfd

TDS

Unit Price:

$100-130/G FOB

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CAS No.:

165800-06-6

Grade:

Reagent Grade

Content:

99%

Port:

qingdao

Brand:

//

Packaging:

5g, 25g, 100g, 500g

Price valid (until):

2026-09-27

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

  • Product Description

  • Seller Information

  • Description

    —— Product Specification ——

    Parameter Specification Details
    Product Name Zoledronic Acid Monohydrate CGP 42446; 1-Hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diphosphonic acid monohydrate
    CAS Number 165800-06-6 165800-06-6
    Molecular Formula C₅H₁₀N₂O₇P₂·H₂O / C₅H₁₂N₂O₈P₂
    Molecular Weight 290.10 g/mol
    Appearance White to off-white powder Visual inspection
    Purity ≥98.0% Determined by HPLC
    Melting Point >200°C (dec.)
    Solubility Soluble in water, 0.1N NaOH; sparingly soluble in organic solvents
    pKa 1.90, 3.15, 6.32, 10.29
    Storage Room temperature, sealed, dry place Protect from moisture
    Packaging 100mg, 500mg, 1g, 5g Amber glass vials
    Application Research use only Bone metabolism research, osteoporosis studies


    —— Product Detail ——

    Product Overview

    • Zoledronic Acid Monohydrate (CAS 165800-06-6), also known as Zoledronate monohydrate, is a potent third-generation bisphosphonate compound . It appears as a white to off-white powder with the molecular formula C₅H₁₂N₂O₈P₂ and a molecular weight of 290.10 g/mol . The compound is also known by its chemical name 1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diphosphonic acid monohydrate


    Packaging & Shipping

                  • Research quantities: 5mg, 10mg, 25mg amber glass vials

                  • Bulk quantities: 50mg, 100mg amber glass bottles

                  • Custom packaging available upon request

                  • Not classified as hazardous material for transport under normal conditions

                  • Product for research and analytical use only; not for human therapeutic use

    Shop CAS 18048-64-1 Eltrombopag Intermediate for Pharmaceutical Research  kr-Detailed Image 1

    Company profile ——


     Shop CAS 1231930-42-9 Abemaciclib Intermediate for Pharma researech use KR-Detailed Image 1

    Jinan Topfull Chemical Co., Ltd. is an international company rooted in China, specializing in the export of chemical products.

    Our company is committed to making every effort to provide ideal chemical products to potential customers worldwide, including but not limited to: organic/inorganic reagents, biological reagents, plant extracts, pharmaceutical intermediates, active pharmaceutical ingredients (APIs), reference standards, reference substances, peptides, and more. Meanwhile, we have established long-term and stable cooperative relationships with university laboratories and off-campus research institutions, enabling us to offer tailored product services based on customers' actual needs.

    We currently support customized services for most product categories, with supply quantities ranging from milligram (mg), gram (g) to kilogram (kg) levels, as well as wholesale. Product purity covers the full spectrum from 90% to 99.9%, providing customers with one-stop convenient services.

    To date, our products have been exported to developed countries such as the United States, Australia, Canada, Mexico, as well as EU member states including France, Germany, and many other countries and regions such as Nigeria, Ghana, Southeast Asia, and other parts of Asia. Our product quality and services have consistently received high praise.

    Looking ahead, our company will continue to serve as a bridge connecting China and the world, delivering high-quality products and services to global customers.

     

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    —— Q&A ——

    Q1: How to confirm the product quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirements for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. If any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What is your MOQ? Is there a discount?
    A: For highvalue products, our MOQ starts from 1g and generally starts from 10g. For other lowprice products, our MOQ starts from 100g and 1kg.
    Q: Is there a discount?
    A: Yes, for larger quantities, we always support with better prices.

    Q5: How to start orders or make payments?
    A: You can send us your Purchase Order (if your company has one), or just send a simple confirmation by email or via Trade Manager. We will then send you a Proforma Invoice with our bank details for your confirmation, and you can make payment accordingly. If you have other preferred payment methods, we are open to discussion and negotiation.



    ECHEMI Editorial Reference
    Zoledronic Acid is a synthetic imidazole bisphosphonate analog of pyrophosphate with anti-bone-resorption activity. A third-generation bisphosphonate, zoledronic acid binds to hydroxyapatite crystals in the bone matrix, slowing their dissolution and inhibiting the formation and aggregation of these crystals. This agent also inhibits farnesyl pyrophosphate synthase, an enzyme involved in terpenoid biosynthesis. Inhibition of this enzyme prevents the biosynthesis of isoprenoid lipids, donor substrates of farnesylation and geranylgeranylation during the post-translational modification of small GTPase signalling proteins, which are important in the process of osteoclast turnover. Decreased bone turnover and stabilization of the bone matrix contribute to the analgesic effect of zoledronic acid with respect to painful osteoblastic lesions. The agent also reduces serum calcium concentrations associated with hypercalcemia.|An imidobisphosphonate inhibitor of BONE RESORPTION that is used for the treatment of malignancy-related HYPERCALCEMIA; OSTEITIS DEFORMANS; and OSTEOPOROSIS.
    Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

    Certificates
    • Zoledronic Acid Monohydrate CAS 165800-06-6 Potent Bisphosphonate for Bone Metabolism and Osteoporosis Research  hfd Certificates 1 TDS

    Basic Info
    Product Name:

    Zoledronic acid hydrate

    Other Name:

    [1-HYDROXY-(1H-IMIDAZOL-1-YL)-PHOSPHONOETHYL] PHOSPHONIC ACID MONOHYDRATE;(1-hydroxy-2-imidazol-1-yl-1-phosphono-ethyl)phosphonic acid hydrate;(1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid monohydrate;PHOSPHONIC ACID, [1-HYDROXY-2-(1H-IMIDAZOL-1-YL)ETHYLIDENE]BIS-, MONOHYDRATE;zoledronic acid hydrate;ZOLEDRONIC ACID MONOHYDRATE;ZoledronicacidforInjection;[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid) monohydrate

    CAS No.:

    165800-06-6

    Molecular Formula:

    C5H12N2O8P2

    InChIKeys:

    FUXFIVRTGHOMSO-UHFFFAOYSA-N

    Molecular Weight:

    290.1

    Exact Mass:

    290.00688934

    UNII:

    6XC1PAD3KF

    DSSTox ID:

    DTXSID10168029

    NCI Thesaurus Code:

    C1699

    Color/Form:

    white to beige

    ATC Code:

    M05BA08

    HScode:

    29332900

    Characteristics
    Melting Point:

    245 °C(dec.)

    Water Solubility:

    H2O: ≥2mg/mL

    Critical Temperature & Pressure:

    2-8°C

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Medetomidine,Medetomidine hydrochloride,D-Lysergic Acid Methyl Ester,SR17018,Fluralaner,GS-441524

    Location:

    RONGSHENG BEIYUANDAJIE 9, LICHENG DISTRICT,JINAN, SHANDONG CHINA

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2022

    Jinan Topfull Chemical Co., Ltd. is a global chemical Industrial and focuses on advanced chemical technology. Specialized in Cosmetic materials, water treatment, fine chemicals and so on. We are looking forward to working together with the people of all circles at home and abroad to seek common development!
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