VcMMAE RC02515
646502-53-6
Pharmaceutical Grade
99%
Royalchem
25kg/drum
Yes
2029-12-31
Pharmaceutical intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceMC-Val-Cit-PAB-MMAE is a precursor of antibody drug conjugate. It contains a thio reactive maleimidocaproyl (MC) group, a protease-sensitive Val-Cit dipeptide, a PABC linker and a MMAE payload. The MMAE is a synthetic antineoplastic agent. It can be attached to a monoclonal antibody (MAB) which directs it toward cancer cells.Basic Info
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Product Name:
VcMMAE
Other Name:VcMMAE;MC-Val-Cit-PAB-MMAE;Maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl-monomethyl auristatin E;4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl((S)-1-(((S)-1-(((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-y;MC-VC-PAB-MMAE;MC-VC-PAB-MMAE,MC-Val-Cit-PAB-MMAE;maleimido-caproyl-val-Cit-PAB-MMAE;VeMMAE
CAS No.:646502-53-6
Molecular Formula:C68H105N11O15
InChIKeys:NLMBVBUNULOTNS-NNNQBTKHNA-N
Molecular Weight:1316.63
Color/Form:White to off-white
Categories:
Characteristics-
Density:
1.196±0.06 g/cm3(Predicted)
Boiling Point:1347.6±65.0 °C(Predicted)
PKA:13.29±0.70(Predicted)
Critical Temperature & Pressure:Sealed in dry,Room Temperature
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 1, Oral
Acute toxicity - Category 1, Dermal
Skin irritation, Category 2
Eye irritation, Category 2
Acute toxicity - Category 2, Inhalation
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H300+H310+H330 Fatal if swallowed, in contact with skin or if inhaled
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P262 Do not get in eyes, on skin, or on clothing.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P284 [In case of inadequate ventilation] wear respiratory protection.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P320 Specific treatment is urgent (see ... on this label).
P319 Get medical help if you feel unwell.
Storage P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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