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Tazemetostat. buy - large image1
Tazemetostat. buy - image1

Tazemetostat.

3 Inquiries

Unit Price: Get Latest Price
CAS No.:

1403254-99-8

Port:

Shanghai

Packaging:

100g/bag

Price valid (until):

2026-03-28

Company Type:
Trader
Location:
China
Qualification:
Main Products:

13-Dimethyladamantane,1-Bromo-35-dimethyladamantane,perhydroacenaphthylene,4-[1,1-bis(4-hydroxyphenyl)ethyl]phenol,CYCLOBUTANE-1,2-DICARBOXYLIC ACID DIMETHYL ESTER, TRANS

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    EPZ-6438 is an effective, selective EZH2 inhibitor with a Ki of 2.5 nM, showing 35-fold greater selectivity for EZH2 over EZH1 and more than 4,500-fold selectivity over 14 other HMTs. In vitro studies show that EPZ-6438 dose-dependently reduces overall H3K27Me3 levels in wild-type or SMARCB1-mutant cells and induces strong antiproliferative effects in MRT cell lines lacking SMARCB1, with IC50 values ranging from 32 nM to 1000 nM. EPZ-6438 induces neuronal differentiation gene expression and cell cycle inhibition while suppressing Hedgehog pathway genes, MYC, and EZH2. In several EZH2-mutant lymphoma cells, the antiproliferative effects of EPZ-6438 are enhanced by hydrocortisone prednisolone or dexamethasone.

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    Items Specifications






    Basic Info
    Product Name:

    Tazemetostat

    Other Name:

    [1,1′-Biphenyl]-3-carboxamide,N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-5-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-4-methyl-4′-(4-morpholinylmethyl)-;N-[(1,2-Dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-5-[ethyl(tetrahydro-2H-pyran-4-yl)amino]-4-methyl-4′-(4-morpholinylmethyl)[1,1′-biphenyl]-3-carboxamide;EPZ 6438;Tazemetostat;E 7438;EPZ 005678;CPI 169;Tazverik

    CAS No.:

    1403254-99-8

    Molecular Formula:

    C34H44N4O4

    InChIKeys:

    InChIKey=NSQSAUGJQHDYNO-UHFFFAOYSA-N

    Molecular Weight:

    572.73756

    Exact Mass:

    572.74

    Characteristics
    PSA:

    83.1

    XLogP3:

    4.2

    Density:

    1.2±0.1 g/cm3

    Flash Point:

    407.9±32.9 °C

    Refractive Index:

    1.589

    Hazard Identification

    Classification of the substance or mixture

    no data available

    GHS label elements, including precautionary statements

    Pictogram(s) no data available
    Signal word

    no data available

    Hazard statement(s)

    no data available

    Precautionary statement(s)
    Prevention

    no data available

    Response

    no data available

    Storage

    no data available

    Disposal

    no data available

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    13-Dimethyladamantane,1-Bromo-35-dimethyladamantane,perhydroacenaphthylene,4-[1,1-bis(4-hydroxyphenyl)ethyl]phenol,CYCLOBUTANE-1,2-DICARBOXYLIC ACID DIMETHYL ESTER, TRANS

    Location:

    Room 1623,Building A, ZhongqiaoCenter,Goverment District,Hefei city,Anhui Province,China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    5-10

    Year of Establishment:

    2019

  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Tazemetostat

    100 G Feb 28, 2026
    Pakistan

    Tazemetostat

    1 KG May 13, 2025
    United States

    Tazemetostat

    25 G Feb 27, 2026
    Post an enquiry for this product
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