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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Adapalene for Sale > High Putiy 99% Min CAS 106685-40-9 Adapalene Raw Material Adapalene
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High Putiy 99% Min CAS 106685-40-9 Adapalene Raw Material Adapalene

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Unit Price: Get Latest Price
CAS No.:

106685-40-9

Grade:

High Purity Grade

Content:

99%

Port:

shanghai

Brand:

XAHNB

Packaging:

1KG

Price valid (until):

2026-04-10

Company Type:
Manufactory
Location:
China
Payment Terms:
L/C,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Product name Adapalene
    CAS No: 106685-40-9
    MOQ:   1KG
    Appearance white powder
    Email Roy@xahnb.com
    WA +86 15891070693

    1. Company Introduction:


      Xian Harmonious Natural Bio- Technology Co., Ltd was founded in 2010, and located in Xlan International Logistics Industrial Zone, Xran City. ShaanxtProvince, China. Now it is the leading researcher and one of the biggest manufacturer in high technology APl area.

    2. There are 8 experts in our research team. We insistin innovation and produce high quality products. And GMP standard workshop and complete stainlessextraction equipment.We have 2 sales deparments over 20 people and sellour products allover the word. We also have strong professional research and developmentteamtalented personnel and completely equipped laboratoy for the quality controlling. Various Detection Device is equipped in HNB company, such as HPLCGC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.

    3. HNB mainly engaged in export of products incuding,wthoutlimitation., pharmaceutical raw materials both for vet and human, also Vitamins, Amino Acidsminerals, peptides, plant extract, feed and food additives. Our company's business is based on Honest, Trustwortly, Constanty to Go Beyond andAchieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends from both home and abroad.
      Passion to innovate, Power to deliver !


    4. SHIPMENT:

      Deliver from warehouse within 1-2 after confirming order.

      Delivery:(Totally cost about 7-10 days)

      Deliver from warehouse within 1-4 after confirming order.

      It cost 1-3 days shipping to port city, Shanghai or Guangzhou.

      It cost 5-8 days from port city to USA by Fedex.(Not include Chinese holiday)


      PACKAGE:

      The internal packing is sealed plastic bag with aluminium foil bag outside. the external packing is EMS waterproof bag.


    5. Before-Sale Service:

      ---Any inquiries will be replied within 12 hours.

      ---Golden Manufactory under ISO/GMP with large stock.

      ---Dedication to quality,We have strict quality control system. 

      ---OEM/ODM Available.

      ---Sample is available for your evaluation & Formulation development.

      ---Low MOQ: No worry about the big MOQ.

      ---Fast Delivery: Narmolly grt it within 7-10 days after confirming the order.

      ---Convenient Payment: Trade Assurance on Alibaba(Visa or Credit card), or TT 

      Shop Hot Selling Veterinary  Praziquantel Powder CAS 55268-74-1 Raw Material-Detailed Image 1

      After-Sale Service:

    6. ---International Authorized Third-Party Test For The Products You Demand.
      ---60 Days Guarantee of quality of goods.


    Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian

    1. International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is the

      leading researcher and one of the biggest manufacturer in high technology API area. 


      There are 8 experts in our research team. We insist in innovation and produce high quality

      products. And GMP standard workshop and complete stainless extraction equipment. 

      We have 2 sales departments over 20 people and sell our products all over the world.


      We also have strong professional research and development team, talented personnel and

      completely equipped laboratory for the quality controlling. Various Detection Device is

      equipped in HNB company, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto

      titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.


      HNB mainly engaged in export of products including, without limitation, pharmaceutical raw

      materials both for vet and human, also Vitamins, Amino Acids, minerals, peptides, plant

      extract, feed and food additives.


      Our company's business is based on Honest, Trustworthy, Constantly to Go Beyond and

      Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends

      from both home and abroad.


      Passion to innovate, Power to deliver!

    2. Shop Hot Selling Veterinary  Praziquantel Powder CAS 55268-74-1 Raw Material-Detailed Image 1
    3. Shop Hot Selling Veterinary  Praziquantel Powder CAS 55268-74-1 Raw Material-Detailed Image 2
    4. Shop Hot Selling Veterinary  Praziquantel Powder CAS 55268-74-1 Raw Material-Detailed Image 3

    5. Shop Hot Selling Veterinary  Praziquantel Powder CAS 55268-74-1 Raw Material-Detailed Image 5
    6. Shop Hot Selling Veterinary  Praziquantel Powder CAS 55268-74-1 Raw Material-Detailed Image 6
    7. Shop Hot Selling Veterinary  Praziquantel Powder CAS 55268-74-1 Raw Material-Detailed Image 7


    • Q1  Can i get some samples? 

      A1  Yes, we can supply the free sample, but the shipping cost be paid by our customers.


      Q2  How to start orders or make payments? 

      A2  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.

    • Payment by T/T,or Paypal or Escrow(Alibaba).


      Q3  How to confirm the Product Quality before placing orders? 

      A3  You can get free samples for some products,you only need to pay the shipping cost or arrange a courier

    • to us and take the samples. You can send us your product specifications and requests,we will manufacture

    • the products according to your requests.


      Q4  What’s your MOQ? 

      A4  Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge

    • is 100% paid.


      Q5  How about delivery leadtime? 

      A5  Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)


      Q6  Is there a discount? 

      A6  Different quantity has different discount.


      Q7  How do you treat quality complaint? 

      A7  First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem

    • caused by us, we will send you free goods for replacement or refund your loss.


      Q8  How to contact us ? 

      A8 You can choose your interested products and send inquiry to us.

    ECHEMI Editorial Reference
    White Crystalline SolidChEBI: A naphthoic acid that is CD437 in which the phenolic hydroxy group has been converted to its methyl ether.Adapalene, a new class of drugs Naphthoic acid derivatives, was developed by France Galdeama Laboratories Company. It first entered into market in June 1996, under the trade name ''Differin'', mainly used for relieving inflammatory skin lesions, adjusting differentiation of hair follicles, gland epithelial cells, and also acne treatment.
    Solid
    Adapalene is a naphthoic acid that is CD437 in which the phenolic hydroxy group has been converted to its methyl ether. It has a role as a dermatologic drug, a non-steroidal anti-inflammatory drug and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a monocarboxylic acid, a member of adamantanes and a naphthoic acid. It derives from a CD437.|Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with Cutibacterium acnes (also known as Propionibacterium acnes). Adapalene is a third-generation topical retinoid used for the treatment of acne vulgaris. Adapalene has similar efficacy but a superior safety profile compared to tretinoin. [Tazarotene] is more efficacious than adapalene but is designated as pregnancy category X and hence is contraindicated in pregnant women. Adapalene can also be combined with benzoyl peroxide (BPO), which possesses bactericidal properties, and either adapalene alone, or adapalene BPO combination products, are commonly used to treat mild-to-severe acne. Differin®, produced by Galderma Labs, was first granted FDA approval on May 31st, 1996, as a 0.1% adapalene topical solution. Differin was later made available as 0.1% gel, cream, or lotion, or 0.3% gel products. On December 8th, 2008, Galderma Labs gained FDA approval for Epiduo®, a 0.1% adapalene, 2.5% BPO combination gel.|Adapalene is a Retinoid.|Adapalene is a topical retinoid-like compound, chemically similar to vitamin A. Although the exact mechanism of action is unknown, adapalene binds to specific retinoic acid receptors in the nucleus, leading to specific gene expression. This agent stimulates skin growth through modulation of cellular differentiation, inflammatory processes and keratinization of follicular epithelial cells. Adapalene may increase dermal sensitivity to ultraviolet radiation. (NCI04)|A naphthalene derivative that has specificity for RETINOIC ACID RECEPTORS. It is used as a DERMATOLOGIC AGENT for the treatment of ACNE.

    Certificates

    Basic Info
    Product Name:

    Adapalene

    Other Name:

    2-Naphthalenecarboxylic acid,6-(4-methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-;6-(4-Methoxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid;CD 271;Adapalene;Differin;6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthalenecarboxylic acid;Differin Gel;6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthoic acid;CD 271 (pharmaceutical);Aclene Gel;Aclene;6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid

    CAS No.:

    106685-40-9

    Molecular Formula:

    C28H28O3

    InChIKeys:

    InChIKey=LZCDAPDGXCYOEH-UHFFFAOYSA-N

    Molecular Weight:

    412.52

    Exact Mass:

    412.52

    EC Number:

    1308068-626-2

    UNII:

    1L4806J2QF

    DSSTox ID:

    DTXSID5046481

    NCI Thesaurus Code:

    C28989

    ATC Code:

    D10AD03|D - Dermatologicals

    HScode:

    2918992090

    Characteristics
    PSA:

    46.5

    XLogP3:

    7.7

    Appearance:

    white to off-white

    Density:

    1.233±0.06 g/cm3(Predicted)

    Melting Point:

    320-322 °C @ Solvent: Tetrahydrofuran

    Boiling Point:

    606.3±55.0 °C(Predicted)

    Flash Point:

    205.9±25.0 °C

    Refractive Index:

    1.655

    Water Solubility:

    Practically insoluble in water;DMSO: >10mg/mL

    Storage Conditions:

    Store at +4°C

    Vapor Pressure:

    1.49E-15mmHg at 25°C

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Skin sensitization, Category 1

    Eye irritation, Category 2

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H317 May cause an allergic skin reaction

    H319 Causes serious eye irritation

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P203 Obtain, read and follow all safety instructions before use.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P333+P317 If skin irritation or rash occurs: Get medical help.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

    Location:

    6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China

    Payment Terms:

    L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    51-100

    Year of Establishment:

    2017

    Company Certificates
    • HNB BiotechISO ISO
    • HNB BiotechISO ISO

    Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian

    International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is the

    leading researcher and one of the biggest manufacturer in high technology API area. 

     

    There are 8 experts in our research team. We insist in innovation and produce high quality

    products. And GMP standard workshop and complete stainless extraction equipment. 

    We have 2 sales departments over 20 people and sell our products all over the world.

     

    We also have strong professional research and development team, talented personnel and

    completely equipped laboratory for the quality controlling. Various Detection Device is

    equipped in HNB company, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto

    titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.

     

    HNB mainly engaged in export of products including, without limitation, pharmaceutical raw

    materials both for vet and human, also Vitamins, Amino Acids, minerals, peptides, plant

    extract, feed and food additives.

     

    Our company's business is based on Honest, Trustworthy, Constantly to Go Beyond and

    Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends

    from both home and abroad.

     

    Passion to innovate, Power to deliver !

  • Inquiry History
    4 Inquiries
    Country Product Purchase Quantity Date Posted
    Australia

    Factory Direct Supply 99% Adapalene powder 106685-40-9 High Quality and Competitive Price

    50 G Nov 10, 2023
    Vietnam

    adapalene

    500 G Jun 1, 2026
    India

    Adapalene

    10 G Jan 21, 2025
    United States

    Adapalene

    200 G Sep 28, 2023
    Post an enquiry for this product
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