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MazdutideCAS 2259884-03-0

5 Inquiries

Unit Price: Get Latest Price
CAS No.:

2259884-03-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Packaging:

box

Price valid (until):

2026-04-20

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Peptide products.

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Pls input...Shop MazdutideCAS 2259884-03-0-Detailed Image 1

    Items Specifications

    Mazdutide is a 34-amino-acid polypeptide drug developed based on the natural gastrin-releasing peptide. It can simultaneously activate the glucagon (GCG) receptor and the glucagon-like peptide-1 (GLP-1) receptor. On one hand, by stimulating the GLP-1 receptor, it promotes insulin secretion, inhibits appetite, delays gastric emptying, and reduces calorie intake; on the other hand, by activating the GCGR, it increases energy consumption, promotes fat breakdown, and simultaneously regulates liver glucose and lipid metabolism, reducing liver fat content. The dual targets work together to achieve the dual effects of weight loss and blood sugar reduction.







    ECHEMI Editorial Reference
    Mazdutide (also known as IBI362 or LY3305677), a novel once-weekly glucagon-like peptide-1 (GLP-1) and glucagon receptor dual agonist, achieved 12-week body weight loss of up to 6.4% at doses up to 6 mg in Chinese adults with overweight or obesity. It is the first GLP-1R/GCGR dual agonist to succeed in Phase 3 trials. As mazdutide's first registrational trial for weight management, the results of GLORY-1 not only further confirm the efficacy and safety of the mazdutide in a large population but also provide high-quality clinical evidence of long-term pharmacotherapy weight management specifically for the Chinese population with overweight or obesity[1].

    Basic Info
    Product Name:

    Mazdutide

    Other Name:

    Mazdutide;Mazdutide acetate;Mazdutide 10mg;Mazdutide 5mg 10mg;LY-3305677;Mazdutide (IBI-362;OXM-3)

    CAS No.:

    2259884-03-0

    Molecular Weight:

    0

    EC Number:

    884-103-0

    Color/Form:

    White to off-white

    Research
    Class:

    Dual GLP-1R/GCGR agonist (long-acting peptide)

    Status:

    Investigational — Phase 3 (China)

    Mechanism:

    A long-acting dual agonist of the GLP-1 receptor (GLP-1R, Ki = 28.6 nM) and glucagon receptor (GCGR, Ki = 17.7 nM). The dual activation provides both glycemic control (via GLP-1R) and increased energy expenditure / hepatic lipolysis (via GCGR), producing weight loss beyond what GLP-1R agonism alone achieves. Administered once weekly.

    EC50 (GLP1R Ki):

    28.6 nM

    EC50 (GCGR Ki):

    17.7 nM

    Source:

    GlpBio: Mazdutide (CAS 2259884-03-0); Innovent Phase Ib results (eClinicalMedicine 2022).DOI

    Clinical Development:

    NCT04930343; NCT05592656

    References
    PubChem:

    PubChem

    Disclaimer:

    Mazdutide is NOT FDA-approved or EMA-approved. It is in Phase 3 clinical trials in China. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptide products.

    Location:

    No. 5, Guoxing Avenue, Lanshan District, Haikou City, Hainan Province. 2nd floor, Hainan Building. No. 206-102, Meilan District Digital Economy Park.

    Average lead Time:

    10

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    11-50

    Year of Establishment:

    2025

  • Inquiry History
    5 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Mazdutide

    30 MG Jul 15, 2024
    United States

    Mazdutide

    25 MG Aug 12, 2026
    Nigeria

    Mazdutide 10mg

    20 PCS Mar 7, 2026
    United Kingdom

    Mazdutide

    1 KG Feb 10, 2026
    United States

    Mazddultide cas

    2 MT Nov 14, 2025
    Post an enquiry for this product
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