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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Megestrol acetate for Sale > High Quality Factory Supply Megestrol acetate Powder CAS 595-33-5
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High Quality Factory Supply Megestrol acetate Powder CAS 595-33-5

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Unit Price: Get Latest Price
CAS No.:

595-33-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

HNB

Packaging:

25kg Cardboard Drum

Price valid (until):

2026-04-30

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Description  


    Methyltestosterone acetate belongs to the 17α-hydroxyprogesterone derivatives and has significant progestogenic activity. The progestogenic effect when taken orally is approximately 75 times that of natural progesterone, and when injected, it is about 50 times.
    Its main pharmacological effects include: inhibiting the release of hypothalamic gonadotropin-releasing hormone (GnRH), reducing the sensitivity of the pituitary gland to GnRH, thereby significantly inhibiting ovulation; changing the nature of cervical mucus to make it viscous and unfavorable for sperm penetration; inhibiting the normal development of endometrial glands and preventing the implantation of fertilized eggs.
    In addition, it also has a significant anti-estrogenic effect, with no estrogen, androgen activity or anabolic effects.
    For hormone-dependent tumors, it can reduce estrogen production by affecting the secretion of pituitary gonadotropins and competitively binding to estrogen receptors, thereby inhibiting the growth of tumor cells.
    Main Applications
    Gynecological disease treatment: Widely used to treat amenorrhea, functional uterine bleeding, endometriosis, etc.
    The specific dosage is adjusted according to the indication. For example, when treating functional uterine bleeding, the initial dose can reach 12mg per day, and the maintenance dose is 4mg per day; when treating endometriosis, an increasing dose regimen can be used, with a treatment course of 6 weeks.
    Malignant tumor treatment: As an adjuvant treatment drug for advanced breast cancer and endometrial cancer.
    For breast cancer, the common dosage is 160mg per day (40mg once, 4 times a day); for endometrial cancer, the dosage range is usually 40mg to 320mg per day.
    Contraception: Combined with ethinyl estradiol, it is used as a component of combined short-acting oral contraceptives.
    Other uses: In the chemical industry, it is also used as an intermediate for the synthesis of other drugs.

     

    Items Specifications
    Name Megestrol acetate
    CAS  595-33-5
    Molecular formula C24H32O4
    Density 384.51


      About Us


    Xian Harmonious Natural Bio- Technology Co., Ltd was founded in 2017, and located in Xian International Logistics Industrial Zone, Xian City. Shaanxi Province, China. Now it is the leading researcher and one of the biggest manufacturer in high technology APl area.

    There are 8 experts in our research team. We insistin innovation and produce high quality products. And GMP standard workshop and complete stainless extraction equipment.

    We have 2 sales deparments over 20 people and sell our products allover the word. We also have strong professional research and development team talented personnel and completely equipped laboratoy for the quality controlling. Various Detection Device is equipped in HNB company, such as HPLCGC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.
    HNB mainly engaged in export of products incuding,without limitation., pharmaceutical raw materials both for vet and human, also Vitamins, Amino Acids minerals, peptides, plant extract, feed and food additives. Our company's business is based on Honest, Trustwortly, Constanty to Go Beyond and Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends from both home and abroad.
    Passion to innovate, Power to deliver !

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      FAQ 


    Q1 Can i get some samples?

    A1 Yes, we can supply the free sample, but the shipping cost be paid by our customers.

    Q2 How to start orders or make payments?

    A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information.

    Payment by T/T,or Paypal or Escrow(Alibaba).

    Q3 How to confirm the Product Quality before placing orders?

    A3 You can get free samples for some products,you only need to pay the shipping cost or arrange a courier

    to us and take the samples. You can send us your product specifications and requests,we will manufacture

    the products according to your requests.

    Q4 What’s your MOQ?

    A4 Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge

    is 100% paid.

    Q5 How about delivery leadtime?

    A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

    Q6 Is there a discount?

    A6 Different quantity has different discount.

    Q7 How do you treat quality complaint?

    A7 First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem

    caused by us, we will send you free goods for replacement or refund your loss.

    Q8 How to contact us ?

    A8 You can choose your interested products and send inquiry to us.

    Certificates

    Basic Info
    Product Name:

    Megestrol acetate

    Other Name:

    Pregna-4,6-diene-3,20-dione,17-(acetyloxy)-6-methyl-;Pregna-4,6-diene-3,20-dione,17-hydroxy-6-methyl-,acetate;17-(Acetyloxy)-6-methylpregna-4,6-diene-3,20-dione;BDH 1298;5071;SC 10363;17α-Acetoxy-6-dehydro-6-methylprogesterone;DMAP;17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate;Megestrol acetate;6-Methyl-6-dehydro-17α-acetoxyprogesterone;6-Methyl-17α-hydroxy-Δ6-progesterone acetate;17α-Acetoxy-6-methylpregna-4,6-diene-3,20-dione;6-Dehydro-6-methyl-17α-acetoxyprogesterone;6-Methyl-17α-acetoxy-4,6-pregnadiene-3,20-dione;17-Acetoxy-6-methylpregna-4,6-diene-3,20-dione;17α-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate;6-Methyl-Δ4,6-pregnadien-17α-ol-3,20-dione acetate;Megace;Niagestin;Megestryl acetate;Magestin;Megeron;Ovarid;MGA;Megestin;Nia;Megestat;Maygace;Megestil;Ovaban;NSC 71423;Megalia

    CAS No.:

    595-33-5

    Molecular Formula:

    C24H32O4

    InChIKeys:

    InChIKey=RQZAXGRLVPAYTJ-GQFGMJRRSA-N

    Molecular Weight:

    384.51

    Exact Mass:

    384.51

    EC Number:

    209-864-5

    UNII:

    TJ2M0FR8ES

    NSC Number:

    71423

    DSSTox ID:

    DTXSID9040683

    NCI Thesaurus Code:

    C1156

    HScode:

    29372390

    Characteristics
    PSA:

    60.4

    XLogP3:

    3.2

    Appearance:

    Crystalline Solid

    Density:

    1.2±0.1 g/cm3

    Melting Point:

    214 °C

    Boiling Point:

    431.17°C (rough estimate)

    Flash Point:

    218.5±30.2 °C

    Refractive Index:

    1.551

    Water Solubility:

    2 µg/mL (at 37 °C for the acetate salt)

    Storage Conditions:

    Refrigerator

    Toxicity:

    LD50 intravenous in mouse: 56mg/kg

    Specific rotation:

    D24 +5° (chloroform)

    Collision Cross Section:

    180.1 Ų [M+H-H2O]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Hazard Identification

    Classification of the substance or mixture

    Carcinogenicity, Category 2

    Specific target organ toxicity – repeated exposure, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H351 Suspected of causing cancer

    H373 May cause damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    Response

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

    Location:

    6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China

    Payment Terms:

    L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    51-100

    Year of Establishment:

    2017

    Certifications:

    ISO,ISO

    Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian

    International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is the

    leading researcher and one of the biggest manufacturer in high technology API area. 

     

    There are 8 experts in our research team. We insist in innovation and produce high quality

    products. And GMP standard workshop and complete stainless extraction equipment. 

    We have 2 sales departments over 20 people and sell our products all over the world.

     

    We also have strong professional research and development team, talented personnel and

    completely equipped laboratory for the quality controlling. Various Detection Device is

    equipped in HNB company, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto

    titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.

     

    HNB mainly engaged in export of products including, without limitation, pharmaceutical raw

    materials both for vet and human, also Vitamins, Amino Acids, minerals, peptides, plant

    extract, feed and food additives.

     

    Our company's business is based on Honest, Trustworthy, Constantly to Go Beyond and

    Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends

    from both home and abroad.

     

    Passion to innovate, Power to deliver !

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    Pakistan

    Megestrol acetate

    15 KG Mar 12, 2024
    Post an enquiry for this product
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